Top 164 Astrazeneca Jobs

Senior Scientist, Cell Therapy Discovery
AstraZeneca —Waltham, MA
- $116,284 - $174,426 a year
- Overtime
- Bachelor of Science
- Analysis skills
- Bachelor's degree
- Paid holidays
- Health insurance
5d
AI Senior Scientist, Rare Cancer Discovery
AstraZeneca —Waltham, MA
- $116,284 - $174,426 a year
- Hybrid work
- Doctor of Philosophy
- 1 year
- Senior level
- Health insurance
- Paid time off
5d
Associate Director, Digital Proteomics and AI Innovation
AstraZeneca —Gaithersburg, MD
- Computer science
- Computer Science
- Doctor of Philosophy
11d
Senior Scientist, Bioinformatics / Computational Biology
AstraZeneca —Cambridge, MA
- $115,992.00 - $172,671.60 a year
- Call employer
- Computer Science
- AWS
- Analysis skills
- Health insurance
- Dental insurance
6d
Translational Medicine Associate Director
AstraZeneca —Waltham, MA
- $135,058.40 - $202,587.60 a year
- 5 years
- Doctor of Philosophy
- Team management
- Health insurance
- Dental insurance
11d
Associate Director, Translational Medicine Lead
AstraZeneca —Waltham, MA
- $142,377.60 - $213,566.40 a year
- Office
- Doctor of Philosophy
- Mentoring
- Health insurance
- Dental insurance
Director, Immuno-oncology Bioinformatics
AstraZeneca —Waltham, MA
- $181,000 - $272,000 a year
- Analysis skills
- Doctor of Philosophy
- Senior level
- Health insurance
- Dental insurance
7d
Drug Product Development Scientist - Viral Vector
AstraZeneca —Gaithersburg, MD
- $92,252 - $138,378 a year
- Bachelor of Science
- Mid-level
- Bachelor's degree
- Health insurance
- Dental insurance
13d
Scientist, Translational Research Science, Haem R&D
AstraZeneca —Cambridge, MA
- $92,252 - $138,378 a year
- Mid-level
- 2 years
- Health insurance
- Dental insurance
11d
Global Product Leader, Late CVRM – Weight Management
AstraZeneca —Cambridge, MA
- $251,610.40 - $377,415.60 a year
- Medicine
- 5 years
- Continuous improvement
- Paid holidays
- Health insurance
6d
Associate Quality Control
AstraZeneca —Frederick, MD
- $55,920 - $83,881 a year
- High school diploma or GED
- Cleaning
- Associate's degree
- Health insurance
- Dental insurance
3d
Medical Lead - Chronic Lymphocytic Leukemia (CLL)
AstraZeneca —Gaithersburg, MD
- $193,281.60 - $289,922.40 a year
- Hybrid work
- Medicine
- 5 years
- Office
- Health insurance
- Dental insurance
Associate Director Global Quality Systems
AstraZeneca —Gaithersburg, MD
- $129,556 - $194,335 a year
- Bachelor's degree
- Senior level
- Leadership
- Paid holidays
- Health insurance
12d
Associate Director, Statistical Science
AstraZeneca —Wilmington, DE
- Management
- Doctor of Philosophy
- Mentoring
3d
Senior Clinical Research Associate
AstraZeneca —Wilmington, DE
- Driver's License
- Bachelor's degree
- Quality control
4d
Director, Theranostics and Radiation Science
AstraZeneca —Boston, MA
- 5 years
- Bachelor of Science
- Office
- Paid holidays
- Health insurance
Senior Group Director Scientist
AstraZeneca —Gaithersburg, MD
- $233,586.40 - $350,379.60 a year
- 7 years
- Office
- Master's degree
- Health insurance
- Dental insurance
7d
Medical Science Liaison - Immunology - Philadelphia/Baltimore
AstraZeneca —Philadelphia, PA
- $160,396 - $240,594 a year
- Medicine
- Mid-level
- Doctor of Philosophy
- Paid holidays
- Health insurance
Scientist/Lab Manager Bioscience Immunology, Respiratory and Immunology
AstraZeneca —Cambridge, MA
- $92,252 - $138,378 a year
- 3 years
- Master's degree
- Senior level
- Health insurance
- Dental insurance
6d
Global Development Medical Director
AstraZeneca —Boston, MA
- $249,827.20 - $374,740.80 a year
- Medicine
- Bachelor of Science
- English
- Health insurance
- Dental insurance
5d

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Senior Scientist, Cell Therapy Discovery

AstraZeneca -
Waltham, MA

Apply Now

Job Details

$116,284 - $174,426 a year
5 days ago

Benefits

Paid holidays
Health insurance
Dental insurance
401(k)
Vision insurance

Qualifications

Advanced cell culture techniques
Immunological assays
Biology research
Data visualization software proficiency
Team leadership
Immunological laboratory techniques
Design of experiments
Flow cytometers
Assay development
Mentoring
Leading team collaboration initiatives
In vivo studies
Cytometry
Technical Proficiency
Project stakeholder communication
Cross-functional communication
Data analysis software

Full Job Description

Location Waltham, Massachusetts, United States Job ID R-256459 Date posted 16/07/2026

Senior Scientist, Cell Therapy Discovery

Waltham, MA, USA

AstraZeneca is a science-led biopharmaceutical company focused on transforming patient outcomes. We seek a curious, collaborative Senior Scientist to advance novel cell therapies for autoimmune and other immunology indications. This hands-on research role requires efficient and competent experimental execution, strong cross-functional communication, and proactive project planning to advance programs in a highly-matrixed environment.

Role overview

You will lead and execute in vitro functional assays, with preferred flexibility to additionally contribute to in vivo studies, to identify and validate cell therapy targets and modalities. You will work with program and project teams to make data-driven decisions to move programs from discovery toward translation. You will also help shape study plans, align stakeholders, and ensure timely delivery of milestones across functions.

Key responsibilities

In vitro discovery: Lead cell therapy target validation and characterize activity of engineered cell therapies using human primary cells and functional co-culture assays; develop and optimize assays; preferred flexibility to additionally contribute to in vivo study design and execution in partnership with in vivo pharmacology.
Data and analytics: Apply a rigorous, data-driven approach to experimental design, mechanism-of-action studies, and decision-making; use appropriate analytics and visualization; document work to high standards.
Cross-functional collaboration: Drive alignment with other teams including protein engineering, genomics, translational science, clinical, and CMC; translate scientific plans into clear objectives, risks, and decision points for clear communication across groups and to leadership.
Project planning and delivery: Collaborate to build and maintain project plans and timelines; manage dependencies and track progress to milestones.
Team and communication: Present results and recommendations to teams and leadership; mentor colleagues and foster a productive lab environment.

Required qualifications and skills

Education: PhD in immunology, cell biology, or related field with 0-5 years experience; or BS or MS with 10+ years of experience in a related field (industry experience strongly preferred).
In vitro expertise: Primary human cell culture and functional cell-based assays; multi‑color flow cytometry; multiplex cytokine detection; assay development.
Extensive autoimmunity and/or inflammation experience: Familiarity with in vitro and in vivo model systems for conditions such as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, inflammatory bowel disease, COPD, fibrosis, etc.
Data proficiency: Strong experimental design, analysis, and interpretation; proficiency with tools such as FlowJo and Prism.
Communication: Proven ability to communicate complex scientific concepts clearly to technical and non-technical stakeholders.
Leadership and collaboration: Strong drive for discovery, scientific curiosity, collaborative mindset; ability to mentor and influence across teams.

Desired qualifications and skills

Cell therapy experience: Work with engineered cell products (e.g., T cell subsets, CAR-based modalities); familiarity with novel CAR or antibody target discovery.
In vivo expertise: Hands-on planning, oversight, and execution of murine in vivo studies using autoimmune disease models; animal handling; standard dosing and engraftment; analysis of pharmacodynamic, immunophenotyping, and efficacy endpoints.
Advanced analytics: Experience integrating complex datasets to guide decisions.

The annual base pay (or hourly rate of compensation) for this position ranges from $116,284 to $174,426. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

17-Jul-2026

Closing Date

22-Jul-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Apply Now

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astrazeneca jobs

Senior Scientist, Cell Therapy Discovery

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