Top 1566 Director Plant Operations Jobs

Quality R&D Operations Drug Substance Director
GlaxoSmithKline —King of Prussia, PA
- Full-time
- 5 years
- Bachelor's degree
- Doctor of Philosophy
Director of Plant Operations
PLI Cards —North Las Vegas, NV
- $180,000 - $190,000 a year
- Full-time
- 5 years
- Ability to sit for extended periods
- Senior level
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Plant Operations Director
Benshaw Inc. —Pittsburgh, PA
- Full-time
- PMP
- Engineering
- Travel
Quality Systems & Assurance Director
Denali Ingredients —New Berlin, WI
- Full-time
- Basic math
- 11+ years
- Ability to lift 50 pounds
- Health insurance
- Dental insurance
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7d
Food Safety Quality Assurance Supervisor
DJs Boudain LLC —Beaumont, TX
- $75,000 - $80,000 a year
- Overtime
- Background check
- Spanish
- Microsoft Excel
- Health savings account
- Relocation assistance
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Assistant Director of Plant Operations-Skilled Nursing
Sunharbor Manor Comprehensive Rehabilitation and Skilled Nursing —Roslyn Heights, NY
- $70,000 - $75,000 a year
- Weekends as needed
- Skilled nursing facility
- Mid-level
- High school diploma or GED
- Health insurance
- Dental insurance
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Director- Environmental and Grounds
Wake County Public School System —Raleigh, NC
- Weekends as needed
- 5 years
- Bachelor of Science
- Office
MASTER CARPENTER (LICENSED) - PLANT OPERATIONS (FT)
Cody Regional Health —Cody, WY
- Full-time
- Microsoft Outlook
- Hospital
- Residential
Director, Plant Operations
Oceans Healthcare —Waco, TX
- CPR Certification
- Psychiatry
- Engineering
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Director, Operations
New Hampshire Ball Bearings, Inc (NHBB) —Peterborough, NH
- $180,000 - $225,000 a year
- Engineering
- Travel
- Senior level
- Health insurance
- Dental insurance
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Manufacturing Foreman
Advanced Fluid Systems —York, PA
- From $30 an hour
- Full-time
- Heavy lifting
- Schematics
- Ability to walk for extended periods
- Health savings account
- Health insurance
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HVAC/Utility Plant Supervisor (updated 7/9/26)
Westfield State University —Westfield, MA
- $3,023.48 a month
- Weekends as needed
- Background check
- 5 years
- Writing skills
- Paid holidays
- Health insurance
4d
Maintenance Director (Plant Operations Director)
Mountain Glen —Mount Vernon, WA
- $26 - $28 an hour
- Weekends as needed
- Background check
- Mid-level
- Apartments
- Disability insurance
- Health insurance
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Director of Plant Operations
MAS Recruiting —Canton, OH
- $60,000 - $75,000 a year
- Full-time
- Psychiatry
- 21 years or older
- Plumbing
- Paid training
- Health savings account
Quick Apply
11d
Director of Facilities and EVS (Danville PA)
Metz Culinary Management —Philadelphia, PA
- $75,000 - $90,000 a year
- Full-time
- 5 years
- English
- Supervising experience
- Relocation assistance
- Health insurance
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Operations Manager
Continental Carbon —Sunray, TX
- $100,000 - $125,000 a year
- Full-time
- Background check
- Up to 50% travel
- 5 years
- Relocation assistance
- Health insurance
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Director of Quality
KCO Resource Management —Syracuse, NY
- $165,000 - $215,000 a year
- Full-time
- Bachelor's degree
- In-person
- Training & development
- Health insurance
- 401(k)
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Director of Plant Operations
Ironside HR —Klamath Falls, OR
- $117,000 - $152,000 a year
- Full-time
- Background check
- Hospital
- Supervising experience
- Relocation assistance
- Health insurance
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4d
Director, Plant Operations
Wysocki Family Farms —Bancroft, WI
- Full-time
- 5 years
- Ability to climb stairs
- High school diploma or GED
Quick Apply
3d
Director of Quality
PIM BRANDS LLC —Somerset, NJ
- $120,000 - $130,000 a year
- Microsoft Excel
- 5 years
- Computer literacy
- Health insurance
- Dental insurance
Quick Apply

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Quality R&D Operations Drug Substance Director

GlaxoSmithKline -
King of Prussia, PA

Apply Now

Job Details

Full-time

Qualifications

Regulatory inspections
Team leadership
Coaching
GMP
Performance management
Manufacturing facility experience
Team development
Bachelor's degree
Pharmaceutical company experience
Quality assurance experience within pharmaceutical industry
Regulatory readiness in healthcare
Quality control experience within pharmaceutical industry
General management
Senior leadership
Pharmaceutical manufacturing facility experience

Full Job Description

At GSK we manufacture and supply reliable, high-quality medicines and vaccines to meet patients’ needs and drive our performance. Our network of 37 medicines and vaccines manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it’s vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply.

We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.

Position Summary

As the Quality R&D Operations Drug Substance Director you will lead quality oversight for drug substance activities in R&D operations at the Upper Merion R&D Pilot Plant. You will work closely with R&D scientists, manufacturing partners, regulatory colleagues and external suppliers. Your team will value clear thinking, practical problem solving, and a focus on patient safety. This role offers growth through cross-functional leadership and the chance to shape processes that accelerate safe, compliant development. You will help unite science, technology and talent to get ahead of disease together.

Responsibilities:

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

Lead quality oversight for drug substance development activities, ensuring compliance with current Good Manufacturing Practices and regulatory expectations.

Own inspection readiness and respond to regulatory questions and observations with timely, clear technical responses.

Manage a team of quality and compliance professionals. Set objectives, coach, and develop people to build capability and resilience.

Drive quality systems and processes for R&D drug substance workstreams, including change control, deviation management, CAPA, and risk assessments.

Support supplier and contract manufacturing oversight, audits, and qualification for drug substance-related activities.

Partner with cross-functional teams to enable product development milestones and timely release of clinical materials.

Why you?

Basic Qualifications:

We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

Bachelor’s degree in a scientific or engineering discipline.

10 or more years of experience in Quality roles in a highly regulated environment (EMA/ FDA/ MHRA).

5 years or more of experience in quality management roles for manufacturing operations.

8 or more years of experience in pharmaceutical quality, R&D quality, or related roles.

Experience with cGMP and US regulatory requirements (FDA) in a development or manufacturing environment.

Prior experience in inspection readiness and regulatory inspections.

5 or more years leading direct reports, including coaching and performance management.

Experience working with third-party suppliers or contract manufacturing organizations.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

Advanced degree (MS, PhD) in chemistry, chemical engineering, pharmaceutical sciences, or a related field.

Experience with drug substance development processes such as fermentation, chemical synthesis, or biologics upstream and downstream processes.

Strong track record in quality systems implementation and process improvement.

Experience supporting clinical supply release and stability programs.

Demonstrated ability to use data to guide decisions and present to senior stakeholders.

Experience working in matrix organizations and partnering across R&D, regulatory, and supply teams.

#LI-GSK

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - [email protected]

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Apply Now

Refine Your Search

Director Plant Operations jobs

Quality R&D Operations Drug Substance Director

Director of Plant Operations

Plant Operations Director

Quality Systems & Assurance Director

Food Safety Quality Assurance Supervisor

Assistant Director of Plant Operations-Skilled Nursing

Director- Environmental and Grounds

MASTER CARPENTER (LICENSED) - PLANT OPERATIONS (FT)

Director, Plant Operations

Director, Operations

Manufacturing Foreman

HVAC/Utility Plant Supervisor (updated 7/9/26)

Maintenance Director (Plant Operations Director)

Director of Plant Operations

Director of Facilities and EVS (Danville PA)

Operations Manager

Director of Quality

Director of Plant Operations

Director, Plant Operations

Director of Quality

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