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Associate Scientist, Protein Engineering & Binder Optimization

Kite Pharma -
Foster City, CA

Apply Now

Job Details

Full-time
$109,650 - $141,900 a year

Benefits

Health insurance
Dental insurance
Paid time off
Vision insurance
Life insurance

Qualifications

Data integrity assurance
Data quality checks
Stability testing
Laboratory project records management
Immunological assays
Molecular Biology
Biochemistry
Biological sample management
Maintaining an organized workspace
Automation
Master's degree in molecular biology
Immunological laboratory techniques
Bioengineering
Master's degree in Biochemistry
Protein analysis (analytical chemistry specialty)
Continuous improvement (laboratory quality control method)
Engineering process optimization
Mid-level
Master's degree
Data quality management
Molecular cloning
Biochemical laboratory techniques
Bachelor's degree
Quality issues
Polyacrylamide gel electrophoresis
Automated systems
Scalability
Implementing research protocols
Bachelor's degree in molecular biology
Mammalian cell culture

Full Job Description

Job Description

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet.

Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.

Job Description

We are seeking a highly motivated and detail‑oriented Associate Scientist to join the Protein Engineering & Binder Optimization group within Kite Research. This role is primarily bench‑focused and execution‑driven, with a strong emphasis on hands‑on laboratory support for high‑throughput protein expression, purification, and analytical characterization.

The Associate Scientist will be a critical contributor to discovery and optimization programs, serving as a reliable experimental operator who enables scale, speed, and data quality across multiple protein engineering efforts. This position is well‑suited for an individual who thrives in a fast‑paced research environment, values rigor and reproducibility, and is excited to build deep technical expertise in protein production and analytics.

Key Responsibilities

High‑Throughput Protein Expression & Purification (Primary Focus)

Execute high‑throughput cloning, expression, and purification of recombinant proteins and binders across multiple formats (e.g., bacterial, mammalian, or yeast systems, as applicable).
Perform parallelized small‑scale and mid‑scale protein production to support binder discovery and optimization workflows.
Prepare purified proteins for downstream applications, ensuring appropriate quality, concentration, and documentation.
Rigorously track samples, constructs, and yields using electronic lab notebooks and sample management systems.

Protein Characterization & Analytics

Perform routine and advanced protein analytical assays, such as SDS‑PAGE, SEC, ELISA, and concentration/quality assessments.
Support binding and functional characterization efforts (e.g., sample preparation for SPR/BLI, cell‑based assays, or functional screens).
Assess protein quality, stability, and suitability for downstream assays; flag issues and propose troubleshooting steps.

Experimental Execution in Discovery Programs

Provide consistent, high‑quality experimental execution in support of binder discovery, optimization, and validation campaigns.
Work from protocols while developing the technical judgment to recognize deviations, failures, or optimization opportunities.
Generate clear, reproducible, and decision‑ready experimental data that feeds directly into program workflows.

Workflow Support & Continuous Improvement

Contribute to the robustness and scalability of protein production and analytical workflows.
Identify opportunities to improve throughput, reproducibility, or data quality through protocol refinement and standardization.
Maintain well‑organized lab spaces, reagents, and shared resources to support efficient team operation.

Collaboration & Communication

Collaborate closely with Scientists and computational partners within the larger Protein Science team
Communicate experiment status, results, and issues clearly in team discussions and written records.
Engage constructively with cross‑functional partners (e.g., Cell Biology, Translational teams) as needed for sample handoff and assay support.

Basic Qualifications

Master’s degree with 2+ years of relevant scientific experience
OR
Bachelor’s degree with 4+ years of relevant scientific experience

Preferred Qualifications

Bachelor’s or Master’s degree in Biochemistry, Molecular Biology, Protein Science, Bioengineering, or a related discipline
Hands‑on laboratory experience in recombinant protein expression and purification
Demonstrated ability to execute repetitive, high‑throughput wet‑lab workflows with accuracy and consistency
Strong attention to detail and commitment to data quality and experimental traceability
Experience with parallelized or automated protein expression/purification workflows
Familiarity with common protein analytics and characterization methods (e.g., SEC, ELISA, biophysical assays)
Experience working in electronic lab notebooks and sample/LIMS systems
Prior experience supporting protein engineering, antibody, or binder discovery programs

Attributes for Success

Highly reliable experimental executor who takes pride in high‑quality bench work
Organized, methodical, and comfortable managing multiple samples and workflows in parallel
Learns quickly from feedback and adapts to evolving experimental needs
Collaborative team member who enables the productivity of Scientists and program teams
Motivated to build deep technical expertise in protein expression, purification, and analytics within a discovery research environment

This role will report into the Protein Engineering & Binder Optimization group complementing it through strong bench‑level execution and experimental scale.

The salary range for this position is: $109,650.00 - $141,900.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

Kite Pharma will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law.

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Kite Pharma provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Kite Pharma Employees and Contractors:

Please apply via the Internal Career Opportunities portal in Workday.

Apply Now

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Job Description

Job Description

Key Responsibilities

High‑Throughput Protein Expression & Purification (Primary Focus)

Protein Characterization & Analytics

Experimental Execution in Discovery Programs

Workflow Support & Continuous Improvement

Collaboration & Communication

Basic Qualifications

Preferred Qualifications

Attributes for Success

For Current Kite Pharma Employees and Contractors: