Top 19635 Application associate engineer Jobs

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Associate Formulation Development Scientist

Phosphorex LLC
Hopkinton, MA

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Job Details

Full-time

Qualifications

Productivity software
Cross-functional collaboration

Full Job Description

Description:

The Associate Scientist is a specialist in the formulation and characterization of particulate based drug delivery systems including lipid and polymeric nanoparticles. The Associate Scientist participates in the development and optimization of formulations to enable cell and tissue targeting contributing to the development of novel therapeutics. They perform hands-on experiments in a laboratory setting, leading the execution of upstream (buffer prep, emulsification, microfluidics) and downstream (buffer exchange, concentration, etc.) formulation development activities. The Associate Scientist is a team player who has laboratory and technical experience with a high attention to detail and desire to work in a fast-paced environment and contribute to a result orientated team.

Role and Responsibilities

Assist in development and optimization of particulate based drug delivery systems to enable delivery of nucleic acids, peptides and small molecules for cell and tissue targeting by:
Preparing polymeric and lipid-based microsphere and nanoparticle formulations via microfluidics, emulsification, etc.
Purification and downstream processing of formulations via dialysis, centrifugation and tangential flow filtration
Characterization of formulations including particle size analysis, zeta potential, drug content, encapsulation efficiency and in vitro release
Evaluating short term stability of frozen and lyophilized formulations to support proof of concept animal studies.
Collaborate with project team(s) to define and execute project plans to facilitate the development and optimization of formulations and processes to support feasibility and pre-clinical studies.
Work collaboratively across multiple departments (Operations, Analytical Services, Process Development) to facilitate project teams’ ability to successfully meet project objectives in a timely and organized fashion.
Prepare and review documents including experimental methods, batch records, SOPs, and reports.
Maintain detailed laboratory notebook.
Adhere to Phosphorex’s Environmental Health and Safety practices and SOPs to maintain a safe, clean, and organized work environment free of safety hazards.

Requirements:

Qualifications and Education Requirements

Bachelor’s degree in chemistry, pharmacy, pharmaceutical sciences, engineering, or other relevant discipline with 0-2 years relevant experience
Strong analytical and critical thinking abilities
Excellent organizational skills, attention to detail and ability to manage multiple priorities in a fast-paced and dynamic environment.
Excellent verbal and written communication skills and ability to collaborate effectively with scientists and engineers working in other disciplines.
Ability to work independently as well as with an interdisciplinary team in a highly collaborative environment.
Demonstrated ability to contribute to multiple projects in parallel.
Well versed with Microsoft Office applications.

Preferred Skills

Prior experience with microfluidic fabrication of Lipid Nanoparticles (LNPs) and/or characterization of LNPs.
Prior experience with biodegradable polymeric systems and development of micro-and nano-particle formulations.
Experience in CDMO environment.

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application associate engineer jobs

Associate Formulation Development Scientist

Associate Engineer

Application Engineer

Associate Engineer

Associate product engineer

Associate AOCS Engineer

Associate Environmental Engineer

Associate Research Engineer

Associate Application Engineer, EHT

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Associate Engineer

Associate/Validation Engineer

Bridge Associate Engineer, Entry Level

Co-op - Associate Engineer

Associate Application Engineer

Nanofabrication Process Engineer

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R&D Associate Engineer

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