Top 256 Computational core director Jobs

Senior Director, AIRx Discovery Biology Lead
Takeda Pharmaceutical —Boston, MA
- $212,000 - $333,190 a year
- Full-time
- Hybrid work
- Management
- 11+ years
- Doctor of Philosophy
- Paid holidays
- Disability insurance
AIRx, Sr. Director, Nonclinical Safety Lead
Takeda Pharmaceutical —Boston, MA
- $212,000 - $333,190 a year
- Call employer
- Hybrid work
- 11+ years
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- Paid holidays
- Disability insurance
Associate Director of AI and Data
Axle —Rockville, MD
- $150,000 - $190,000 a year
- Azure
- Computer Science
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Pathology Sr. Director
Amgen —Remote
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- 5 years
- Master's degree
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Computational Scientist
Stowers Institute for Medical Research —Kansas City, MO
- Email
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Technician, Sequencing & Bioinformatics - Genome Core (Relocation Assistance Available!)
Whitehead Institute —Cambridge, MA
- $65,000 - $90,000 a year
- Full-time
- Bachelor of Science
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- 3 years
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Director, Head of Drug Discovery
Arcturus Therapeutics Inc —San Diego, CA
- $191,000 - $250,000 a year
- Full-time
- Computer literacy
- 11+ years
- Analysis skills
- Employee stock purchase plan
- Health insurance
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7d
Director/Senior Director, Molecular Discovery
Lila Sciences —Cambridge, MA
- $202,400 - $323,400 a year
- 11+ years
- Doctor of Philosophy
- Senior level
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Computational Biologist II, External Collaborations
Immunai —New York, NY
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- 2 years
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Principal Scientist/Associate Director, Proteomics (On-Site)
Neomorph, Inc. —San Diego, CA
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- 8 years
- Doctor of Philosophy
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Senior Director / Vice President, Chemistry Experiment
Lila Sciences —Cambridge, MA
- $204,000 - $346,000 a year
- 11+ years
- Doctor of Philosophy
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Director, Data Science and Machine Learning
Flagship Pioneering, Inc. —Cambridge, MA
- $232,000 - $319,000 a year
- Master's degree
- AWS
- Doctor of Philosophy
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Associate Director, Biopharmaceutics
AbbVie —North Chicago, IL
- $141,500 - $268,500 a year
- Full-time
- Hybrid work
- Master's degree
- 8 years
- Bachelor's degree
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Computing Division Director
Pacific Northwest National Laboratory —Richland, WA
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- Full-time
- Computer science
- Computer Science
- Bachelor of Science
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Director and Group Head, Applied AI
Novartis —Cambridge, MA
- $194,600 - $361,400 a year
- Full-time
- Hybrid work
- Management
- 11+ years
- Office
- Disability insurance
- Health insurance
Director, Clinical Science
Pathos AI —New York, NY
- $200,000 - $240,000 a year
- Remote
- Medicine
- 5 years
- Office
Facility Director - CryoEM & Nanoimaging Facility - Assistant Research Professor
Rutgers University —Piscataway, NJ
- $93,588 - $117,000 a year
- Full-time
- Doctoral degree
- 5 years
- Office
- Paid holidays
- Dental insurance
Associate Director, Data Science
Rhythm Pharmaceuticals —Boston, MA
- Full-time
- 5 years
- SQL
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7d
Computational Physicist
Type One Energy —Madison, WI
- $0 a year
- Full-time
- Hybrid work
- C++
- Doctor of Philosophy
- Senior level
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Director, Mental Health
Foundation for the National Institutes of Health (FNIH) —North Bethesda, MD
- $185,000 - $225,000 a year
- Full-time
- Hybrid work
- Medicine
- Psychiatry
- Office
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Senior Director, AIRx Discovery Biology Lead

Takeda Pharmaceutical -
Boston, MA

Apply Now

Job Details

Full-time
$212,000 - $333,190 a year

Benefits

Paid holidays
Disability insurance
Health insurance
Dental insurance
Tuition reimbursement
Paid time off
Vision insurance
401(k) matching
Volunteer time off
Life insurance

Qualifications

AI models
Program design
Data Integration (Data management)
Management
Cell & molecular biology research
AI tools proficiency
Investigational new drug (IND) applications
Machine learning projects
Doctor of Philosophy
Pharmaceutical company experience
Data interpretation
Experimental design
Cross-functional collaboration
Translational research
Pharmaceutical research experience
Cross-functional communication

Full Job Description

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Senior Director, AIRx Discovery Biology Lead

Takeda Research is constructing the Discovery Automation & Robotics (DAR) group built on AI, automation, new ways of working, and talent with the singular vision of delivering differentiated medicines to the clinic at speed and cost. To catalyze these efforts, Takeda is creating two complementary units: AI Research Accelerator (AIRx) and The Discovery Automation & Robotics (DAR) group.

AIRx will consist of a dedicated group of experienced drug hunters with the autonomy of a biotech and the resources of a leading pharmaceutical company. It is designed to incubate the future AI-powered operating models and deliver candidates to the clinic at industry leading speed and success rates.

Purpose

Biology is the strategic core of every AIRx program — As Discovery Biology Lead, you will set the mechanistic and translational foundation that determines whether a program deserves to advance, guiding the team from target hypothesis to clinical hypothesis with the intellectual authority that only deep disease biology expertise can provide.

Responsibilities include directing CRO partners with precision and accountability to generate high-quality, interpretable data that feeds into AI-powered DMTA cycles, and connecting experimental biology to translational strategy and clinical outcomes.

The AIRx Discovery Biology Lead combines deep scientific expertise with the agility to thrive in an externalized, AI-powered operating model — leveraging biological depth and pragmatism to direct and integrate biology at speed, while role modeling new ways of working in Discovery Automation & Robotics (DAR) group.

Accountabilities

Own the disease biology and target validation strategy across the AIRx portfolio; ensure all programs have mechanistic rationale, clear differentiation, and clinical line of sight
Define translational biomarker strategies supporting go/no-go decisions and future clinical development
Design and provide strategic oversight of CRO-executed in vitro and in vivo biology studies; critically evaluate data packages for scientific quality and decision-readiness
Integrate biology data into AI-enabled DMTA cycles alongside medicinal/computational chemists, DMPK, safety, and structural biology
Challenge scientific assumptions across the team; ensure biological integrity and mechanistic depth underpin all program decisions
Represent biology perspectives at Takeda governance forums; contribute to IND-enabling biology packages
Stay current with disease biology and the competitive landscape; proactively inform the team of relevant developments
Shape how biology is practiced in the AIRx model — your ways of working here will become the template for Takeda Research’s future operating model

Qualifications & Competencies

PhD in cell biology, molecular biology, pharmacology, or closely related discipline
12-15+ years of drug discovery experience with a strong track record in target validation and disease biology
Proven contributions to IND filings; experience supporting IND-enabling biology packages
Track record designing and managing externalized CRO biology programs; ability to scope, oversee, and critically interpret study data
Ability to connect target biology to clinical hypothesis and translational strategy
AI/ML data integration experience; comfortable working with large multi-source datasets
Experience in at least one therapeutic area represented across the Takeda Research portfolio
Excellent cross-functional collaboration skills; able to operate effectively in a lean, fast-paced team

ADDITIONAL INFORMATION

The position will be based in Cambridge, MA. This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$212,000.00 - $333,190.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Apply Now

Refine Your Search

computational core director jobs

Senior Director, AIRx Discovery Biology Lead

AIRx, Sr. Director, Nonclinical Safety Lead

Associate Director of AI and Data

Pathology Sr. Director

Computational Scientist

Technician, Sequencing & Bioinformatics - Genome Core (Relocation Assistance Available!)

Director, Head of Drug Discovery

Director/Senior Director, Molecular Discovery

Computational Biologist II, External Collaborations

Principal Scientist/Associate Director, Proteomics (On-Site)

Senior Director / Vice President, Chemistry Experiment

Director, Data Science and Machine Learning

Associate Director, Biopharmaceutics

Computing Division Director

Director and Group Head, Applied AI

Director, Clinical Science

Facility Director - CryoEM & Nanoimaging Facility - Assistant Research Professor

Associate Director, Data Science

Computational Physicist

Director, Mental Health

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