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Senior Scientist / Engineer: Immunology, Nucleic Acid Therapeutics, Synthetic Biology, & Cell Engineering

Intertwine Associates
Remote

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Job Details

Full-time
$90,000 - $220,000 a year

Qualifications

Content creation for technical audiences
Presentation software
Presentations for conferences or internal meetings
Doctor of Philosophy
Research data analysis
Technical writing experience within technology
Research findings presentation

Full Job Description

Explore what happens when ideas Intertwine

At Intertwine Associates, we live by a simple promise: We show up ready to work. We partner with organizations across government, management, strategy, and technology to deliver operational efficiency and measurable impact—particularly in domains where foundational science meets real‑world execution. Learn more at www.intertwineassociates.com

Key Role

Intertwine Associates is seeking a Senior Scientist / Engineer to support advanced research and development initiatives within the Advanced Research Projects Agency for Health (ARPA-H). This role supports an ARPA-H Program Manager leading ambitious, high-risk, high-reward programs focused on accelerating transformative health outcomes through cutting-edge biotechnology, therapeutic innovation, and bioengineered solutions to complex health challenges.

In this role, you will collaborate closely with the Program Manager and broader government, technical, and performer teams to support the development, funding, execution, and management of new and existing R&D programs. The position is focused on novel therapeutic modalities and bioengineered approaches, including nucleic acid-based prophylactics and therapeutics, synthetic biology, cell engineering, immunology, host biology, polymers, minerals, and related areas. This role may cover in vivo cell engineering; protein editing; tunable therapies that sense and respond to cellular stimuli; trans-omic sequencing platform development to enable total molecular analysis of individual cells for research, diagnostics, and therapeutic design; and detection and removal of toxic substances from the body. This role is well suited for scientists and engineers who thrive in dynamic environments and enjoy translating deep technical insight into program-level impact.

Core Responsibilities

Serve as a senior scientific and technical advisor to the Program Manager, supporting the development and execution of new and existing ARPA-H R&D programs
Conduct rigorous evaluations of the current scientific and technical landscape to identify research gaps, portfolio opportunities, and critical needs aligned with the ARPA-H mission
Support programs and projects related to immunology, nucleic acid therapeutics, synthetic biology, cell engineering, gene regulation, biomaterials, microbiome science, toxicology, and related biotechnology areas
Monitor and assess performer progress against defined technical milestones, deliverables, and quantitative performance metrics
Critically review complex scientific, technical, and programmatic data using strong logical and analytical reasoning
Read, synthesize, and distill large volumes of complex information into concise, executive-ready briefings for technical and non-technical audiences
Support program execution through documentation, internal reporting, briefing development, data collection, and coordination across multidisciplinary teams
Assist with technical reviews, landscape assessments, performer evaluations, and programmatic analysis in health-related research areas
Integrate into an existing ARPA-H support team while also operating independently in support of complex technical R&D efforts
Support coordination across cooperative agreements, Other Transaction awards, milestone-based contracts, FFRDCs, interagency efforts, and commercialization activities
Travel within CONUS as needed, approximately 10–20%, to support program reviews, meetings, and stakeholder engagements

Basic Qualifications

PhD in immunology, nucleic acid therapeutics, synthetic biology, analytical chemistry, materials science, applied biotechnology, or a closely related field
Experience in one or more of the following areas: immunology, nucleic acid-based prophylactics and therapeutics, nucleic acid delivery, synthetic biology, cell engineering, gene regulation, biochemistry, analytical chemistry, polymer chemistry, materials science, toxicology, cell biology, structural biology, biomaterials, nanotechnology, microbiome science, or microbial communities
Strong technical writing skills, with the ability to communicate complex scientific ideas clearly to broad audiences
Demonstrated ability to digest basic and applied research across biotechnology domains and translate scientific insights into health capability gaps, program risks, and actionable recommendations
Strong logical, analytical, and critical thinking skills, including the ability to evaluate complex scientific and technical data
Professional curiosity, continuous drive for learning, and willingness to explore emerging biotechnology literature
Ability to synthesize large volumes of complex information into actionable, decision-ready insights
High level of comfort operating in fast-paced, high-pressure R&D environments
Strong PowerPoint and Excel skills, including the ability to create slides, analyses, and supporting materials quickly during meetings or time-sensitive discussions
Ability to work independently and collaboratively as part of an integrated technical and programmatic team
Ability to obtain and maintain a federal government Public Trust

Additional Qualifications (Preferred)

Experience with animal studies, clinical studies, diagnostic development, therapeutic development, regulatory requirements, and test and evaluation
Previous experience with basic and applied research in biotechnology, therapeutics, diagnostics, or related health fields
Experience coordinating independent verification and validation activities
Experience supporting programs involving cooperative agreements, Other Transaction awards, milestone-based contracts, FFRDCs, interagency efforts, or commercialization pathways
Prior support to executives or senior leaders managing large-budget R&D programs
Expertise anticipating and mitigating ethical, legal, and societal implications of high-profile research efforts
Experience bridging scientific discovery, product development, and program execution
Prior experience working with government agencies or federally funded R&D programs

Intertwine Associates LLC – Equal Employment Opportunity Statement

Intertwine Associates LLC is an Equal Opportunity Employer. We are committed to fostering a diverse and inclusive workplace where all individuals are treated with respect and dignity. Employment decisions are made without regard to race, color, religion, sex (including pregnancy, sexual orientation, and gender identity), national origin, age, disability, genetic information, veteran status, citizenship status, or any other characteristic protected by applicable law.

Intertwine Associates LLC proudly supports U.S. Federal Government missions by providing exceptional technical talent and services. Certain roles may require U.S. citizenship or specific security clearances in accordance with federal contract requirements.

The pay range for this role is:

90,000 - 220,000 USD per year (Remote (United States))

Quick Apply

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