Top 7786 Method development scientist Jobs

Scientist/Senior Scientist - Biology
IASO BIOTHERAPEUTICS USA LTD —Pleasanton, CA
- From $90,000 a year
- Full-time
- 3 years
- Doctor of Philosophy
- In-person
- Health insurance
- Dental insurance
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2d
Aerosol Scientist
Johns Hopkins Applied Physics Laboratory (APL) —Laurel, MD
- $100,000 - $245,000 a year
- Full-time
- Engineering
- Mid-level
- Doctor of Philosophy
- Disability insurance
- Health insurance
8d
Organizational Psychologist
Central Intelligence Agency —Washington, DC
- $179,891 - $288,000 a year
- Full-time
- 5 years
- Doctor of Philosophy
- Travel
- Health insurance
- Dental insurance
Stem Cell Biologist
Confidential Healthcare Company —Los Angeles, CA
- $95,000 - $135,000 a year
- Full-time
- Mid-level
- Office
- Master's degree
- Health insurance
- Dental insurance
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1d
Analytical Chemist
Harrell Industries, Inc. —Rock Hill, SC
- $57,000 - $68,000 a year
- Full-time
- Background check
- Bachelor of Science
- Mid-level
- Health insurance
- 401(k)
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7d
Scientist I Biopreservation
Biolife Solutions, Inc. —Bothell, WA
- $109,593 - $158,910 a year
- Full-time
- Background check
- Bachelor of Science
- Pass drug screening
- Disability insurance
- Health insurance
Research & Development Scientist
Biowy —Lake Forest, CA
- Master's degree
- Analysis skills
- Doctor of Philosophy
Research Scientist
University of Texas Health Science Center at San Antonio —San Antonio, TX
- Full-time
- Mid-level
- Bachelor's degree
14d
Beverage Scientist
Shasta Beverages, Inc —Hayward, CA
- $110,000 a year
- Full-time
- Microsoft Excel
- Ability to walk for extended periods
- Computer literacy
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Beverage Scientist
National Beverage Corp —Hayward, CA
- $110,000 a year
- Full-time
- Microsoft Excel
- Ability to walk for extended periods
- Computer literacy
Quick Apply
Beverage Scientist
National Beverage Corp. —Hayward, CA
- From $115,000 a year
- Full-time
- Background check
- Microsoft Excel
- Ability to walk for extended periods
- Health savings account
- Health insurance
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Research Analytical Scientist
Amphastar Pharmaceuticals Inc. —Chino, CA
- $33 - $43 an hour
- Full-time
- Microsoft Word
- Microsoft Excel
- Computer literacy
- Health savings account
- Health insurance
Quick Apply
Pathology Research Scientist
Vertex Pharmaceuticals —Boston, MA
- $105,600 - $158,400 a year
- Full-time
- 7 years
- Analysis skills
- Quality control
- Loan repayment program
- Dental insurance
Product Development Engineering Scientist
Vertex Pharmaceuticals —Boston, MA
- $105,600 - $158,400 a year
- Full-time
- Bachelor of Science
- Mid-level
- 2 years
- Loan repayment program
- Dental insurance
Product Development Engineering Senior Scientist - Medical Device & Combination Products
Vertex Pharmaceuticals —Boston, MA
- $126,600 - $189,800 a year
- Full-time
- Bachelor of Science
- Engineering
- Bachelor's degree
- Loan repayment program
- Dental insurance
Analytical Science and Technology Senior Scientist
Vertex Pharmaceuticals —Boston, MA
- $120,000 - $180,000 a year
- Full-time
- Hybrid work
- Master's degree
- Analysis skills
- Bachelor's degree
- Loan repayment program
- Dental insurance
Fellowship Program
TeselaGen Biotechnology —Remote
- Remote
- Computer Science
- Bachelor of Science
- Bachelor's degree
Associate Scientist
Vivodyne —San Francisco, CA
- $95,000 - $135,000 a year
- Full-time
- Mid-level
- Master's degree
- Bachelor's degree
Scientist
Cape Fox Facilities Services —Bethesda, MD
- $42 - $58 an hour
- Full-time
- Mid-level
- Master's degree
- Mentoring
- Paid holidays
- Disability insurance
Pharmaceutical Development Scientist I
CATO SMS —Cary, NC
- Full-time
- Bachelor of Science
- English
- Mid-level
Quick Apply

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Scientist/Senior Scientist - Biology

IASO BIOTHERAPEUTICS USA LTD
Pleasanton, CA

Quick Apply

Job Details

Full-time
From $90,000 a year
2 days ago

Benefits

Health insurance
Dental insurance
401(k)
Paid time off
Vision insurance

Qualifications

Biology
Biological safety protocols
Research design
Laboratory experiment design
Advanced cell culture techniques
Molecular Biology
Research project design
Molecular cloning
Research project technical leadership
Doctor of Philosophy
Master of Science
Engineering research
Design engineering
Data interpretation
Experimental design
Chemistry, manufacturing & controls
Technical project management
Technical troubleshooting support
Production troubleshooting

Full Job Description

Scientist / Senior Scientist – Viral Vector Engineering (Lentiviral Systems)

About the Role

We are seeking a highly motivated Scientist / Senior Scientist with deep expertise in lentiviral vector engineering, cell therapy, and gene delivery technologies. The ideal candidate will play a leading role in designing, engineering, optimizing, and evaluating next-generation lentiviral systems for cell and gene therapy applications.

This position requires an individual who can independently conceive scientific strategies, design viral vectors from first principles, execute complex experiments, troubleshoot technical challenges, and drive projects from concept to completion.

Demonstrated experience designing and engineering lentiviral packaging systems beyond routine cloning or virus production is highly preferred.

Key Responsibilities

Independently design, engineer, and optimize lentiviral vector systems for research and therapeutic applications.
Develop novel lentiviral packaging plasmids, transfer vectors, and helper constructs.
Design and generate new viral variants, envelope modifications, pseudotypes, and vector mutations to improve transduction efficiency, specificity, safety, and manufacturability.
Lead molecular cloning, plasmid engineering, sequence optimization, and vector validation.
Design and execute experiments to evaluate viral infectivity, tropism, gene expression, and functional performance.
Independently identify technical bottlenecks and develop innovative solutions through systematic troubleshooting.
Optimize lentiviral production using HEK293T and other producer cell lines.
Perform lentiviral transduction of multiple primary and immortalized cell types, including human PBMCs and immune cells.
Collaborate with multidisciplinary teams to support cell therapy and gene therapy programs.
Maintain detailed documentation and present scientific findings internally and externally.
Contribute to intellectual property generation, patent applications, and scientific publications.

Required Qualifications

Ph.D. in Molecular Biology, Virology, Cell Biology, Immunology, Biomedical Engineering, or a related discipline (Scientist level). Exceptional candidates with an M.S. and extensive industrial experience will also be considered.
3–5+ years of hands-on experience in lentiviral vector development within industry or advanced academic research.
Demonstrated ability to independently design and modify lentiviral vectors, including packaging plasmids, transfer vectors, regulatory elements, and viral components.
Strong experience in molecular cloning, plasmid construction, sequence optimization, mutagenesis, and vector engineering.
Extensive experience producing high-titer lentivirus using HEK293T or equivalent producer cell systems.
Proven experience transducing primary human cells, particularly PBMCs, T cells, stem cells, and other difficult-to-transduce cell types.
Strong understanding of viral biology, transgene expression, promoter selection, vector architecture, and biosafety considerations.
Demonstrated ability to independently design experiments, interpret data, troubleshoot complex technical issues, and drive projects with minimal supervision.
Excellent communication, documentation, and project management skills.

Preferred Qualifications

Candidates with one or more of the following experiences are strongly encouraged to apply:

Inventor or co-inventor on patents related to viral vectors, gene delivery, or cell therapy.
Experience designing novel lentiviral systems with improved specificity, tropism, targeting, or manufacturing performance.
Experience utilizing AI-assisted tools or computational methods for vector design, sequence optimization, protein engineering, or experimental planning.
Experience with CAR-T, in vivo CAR-T, CAR-NK, or other engineered immune cell platforms.
Experience culturing and differentiating induced pluripotent stem cells (iPSCs), including downstream differentiation into therapeutically relevant cell types.
Experience with antibody engineering, recombinant antibody development, or biologics.
Familiarity with CRISPR/Cas-based genome editing technologies.
Experience supporting preclinical development, technology transfer, or CMC activities.
Experience working under GLP/GMP or translational research environments.

Ideal Candidate

The successful candidate is a creative scientist who enjoys solving challenging biological problems and has demonstrated the ability to independently transform scientific concepts into robust experimental solutions. We are particularly interested in candidates who have a proven track record of engineering next-generation lentiviral systems rather than simply producing standard lentiviral vectors.

If you are passionate about advancing cell and gene therapy through innovative vector engineering, we would love to hear from you.

Pay: From $90,000.00 per year

Benefits:

401(k)
Dental insurance
Health insurance
Paid time off
Vision insurance

Work Location: In person

Quick Apply

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method development scientist jobs

Scientist/Senior Scientist - Biology

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