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Director Biology/Pharmacology

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Company: Relypsa

Location: Redwood City, CA

Date Posted: May 29, 2014

Source: BioSpace

Relypsa is a clinical-stage biopharmaceutical company focused on the development and commercialization of non-absorbed polymeric drugs to treat disorders in the areas of renal, cardiovascular and metabolic diseases.

The Director of Biology / Pharmacology will play a central role in helping to define the strategic direction of drug discovery and development at Relypsa. Under the guidance of senior management of the Company, he or she will be responsible for planning and managing discovery and non-clinical research activities in the fields of biology and pharmacology. The successful candidate will demonstrate a deep understanding of the drug discovery and development process, with a proven track record in leading cross-functional teams and moving compounds into the clinic.

RESPONSIBILITIES:

Contribute to the scientific perspective and leadership in support of discovery efforts at Relypsa, Inc.

Support building and delivering a sustainable flow of development candidates for clinical development consistent with agreed strategies

- Define, evaluate and exploit ...

Relypsa is a clinical-stage biopharmaceutical company focused on the development and commercialization of non-absorbed polymeric drugs to treat disorders in the areas of renal, cardiovascular and metabolic diseases.

The Director of Biology / Pharmacology will play a central role in helping to define the strategic direction of drug discovery and development at Relypsa. Under the guidance of senior management of the Company, he or she will be responsible for planning and managing discovery and non-clinical research activities in the fields of biology and pharmacology. The successful candidate will demonstrate a deep understanding of the drug discovery and development process, with a proven track record in leading cross-functional teams and moving compounds into the clinic.

RESPONSIBILITIES:

Contribute to the scientific perspective and leadership in support of discovery efforts at Relypsa, Inc.

Support building and delivering a sustainable flow of development candidates for clinical development consistent with agreed strategies

- Define, evaluate and exploit therapeutic targets to identify leads
- Evaluate potential drug candidates for in-licensing

Ensure the appropriate conduct of Biology and Pharmacology studies and high-quality reporting to regulatory authorities from IND to launch

Play an active role in the evaluation of potential drug candidates for in-licensing

Contribute to portfolio prioritization and critical assessment of risk, cost and timing for each program

Effectively partner with all functions and disciplines (Chemistry, CMC, toxicology, clinical, regulatory, commercial, business development) to achieve corporate objectives

Support a culture of innovation that promotes teamwork and optimizes performance

- Work to attract, retain and develop a world-class research team
- Maintain scientific quality and data integrity
- Secure state-of-the-art research tools and capabilities allowing Relypsa to maintain industry competitiveness and facilitate discovery and development activities

Select and manage relationships with an adequate number of third party vendors to carry out experiments and studies, while managing delivery risk. PhD in Biology or Pharmacology. 10-15 years of experience in both discovery and early development settings

Deep understanding of drug discovery and development. Demonstrated track record in leading cross-functional teams and moving compounds into the clinic is a requisite

Knowledge and experience of the fields of renal, cardiovascular or metabolic diseases and ability to quickly adapt to new therapeutic targets

Experience in polymer drug discovery and development is preferred

Exceptional verbal/written communication, time/resource management, interpersonal, organization and leadership skills are also required.

As an employee of Relypsa, you will actively contribute to the development of potential new products. We provide opportunities for all employees to collaborate, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs and stock options reflect Relypsas high regard for our employees.

NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.
To apply for this position, please send your resume to recruiting@relypsa.com.

EOE

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