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Staff Scientist Cell Biology

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Company: Science Careers

Location: Grand Island, NY

Date Posted: September 8, 2014

Source: Science Careers

Act as the technical lead for cell culture media and process optimization projects. Summarize and prepare data for external presentation including, but not limited to client teleconferences or visits, internal presentations and external publications.

Essential Functions
* Independently design experimental plans, lead study execution, analyze experimental data, generate laboratory protocols and write technical reports
* Troubleshoot and solve problems in the design/execution of service projects
* Interact with other internal departments (i.e., Marketing, Business Development, Technical Service and/or Operations) and external collaborators to coordinate creation and presentation of data sets
* Project Leader responsibilities including tracking of project progress, resources and issues
* Support technical consultation with customers in person, by phone/e-mail, and through presentation of data at client meetings, scientific conferences (external and internal), and other publication when appropriate
* Maintain accurate lab notebook and training file in accordance with relevant Thermo Fisher required standards to support patent application and defense ...

Act as the technical lead for cell culture media and process optimization projects. Summarize and prepare data for external presentation including, but not limited to client teleconferences or visits, internal presentations and external publications.

Essential Functions
* Independently design experimental plans, lead study execution, analyze experimental data, generate laboratory protocols and write technical reports
* Troubleshoot and solve problems in the design/execution of service projects
* Interact with other internal departments (i.e., Marketing, Business Development, Technical Service and/or Operations) and external collaborators to coordinate creation and presentation of data sets
* Project Leader responsibilities including tracking of project progress, resources and issues
* Support technical consultation with customers in person, by phone/e-mail, and through presentation of data at client meetings, scientific conferences (external and internal), and other publication when appropriate
* Maintain accurate lab notebook and training file in accordance with relevant Thermo Fisher required standards to support patent application and defense as well as other international standards (e.g., ISO compliance, GLP/GMP requirements, etc.)
* Investigate, create, and develop new methods and technologies for project advancement
* Maintain high level of professional expertise through familiarity with current scientific literature, competing technologies and/or products and attendance of scientific seminars and meetings

Nature and Scope
* Exercise judgment within broadly defined practices and policies in selecting methods and techniques for obtaining solutions
* Direct and control the activities of multiple projects. Perform duties independently with only general direction given on new projects
* Works on complex problems of diverse scope where analysis of situations or data requires an in-depth evaluation of various factors
Measures of Contribution/Impact
* Contribution is measured through, but not limited to, completion of assigned projects, peer reviewed publications and presentations (e.g., talks and posters) at national and international meetings
* Technical Excellence: Maintains substantial knowledge of principles and theories. Exhibits creativity, foresight and mature judgment in conducting research programs/projects
Key knowledge/skills/abilities:
* Chemical, biochemical and physical interactions of cell culture media and reagent components. Scale-up modeling of formulations and systems
* Media/reagent formulation experience is desirable
* Familiarity in the operation of small scale mammalian cell culture, bench-top stirred tank bioreactors, WAVE bioreactors and other process development laboratory equipment is desirable
* Familiarity of assay detection systems for protein characterization such as ELISA, Octet, etc
* Excellent organizational skills, including the ability to efficiently evaluate, prioritize and handle multiple and changing projects and priorities
* Excellent verbal and written communication skills and the ability to interpret and summarize scientific results in a clear, concise, accurate manner
* Demonstrated ability to formulate and solve problems
* Statistical Design of Experiment (DOE) experience
* Demonstrated competence in data analysis, research design, troubleshooting, and the evaluation of new techniques and procedures for manufacturing reagents, systems, products or technologies
* Frequent technical interaction both within the company at all levels, with subordinates, colleagues, members of other departments, with outside scientific collaborators through seminars and publications of research, and customers through site visits and scientific meetings
Working Conditions:
* ?Works in a laboratory environment; is required to lift up to 40 lbs
* May be required to stand for long periods of time while performing duties; able to work safely with chemicals and hazardous materials
* Must be able to work overtime and flexible shifts
* Travel Requirements: 5-10%

Minimum Qualifications (must have)

* PhD with 1 year of experience, or Master's degree with 4 plus years of experience in related industry
* Chemical, biochemical and physical interactions of cell culture media and reagent components
* Familiarity in the operation of small scale mammalian cell culture, bench-top stirred tank bioreactors
* Excellent verbal and written communication skills and the ability to interpret and summarize scientific results in a clear, concise, & accurate manner
* Statistical Design of Experiment (DOE) experience
* Proven ability to lead and provide work direction
* Demonstrated competence in data analysis, research design, troubleshooting, and the evaluation of new techniques and procedures for manufacturing reagents, systems, products or technologies

Preferred Qualifications (nice to have)
Experience with high-throughput technologies (such as the ambr system), previous experience with cell types used in cell therapy applications (T cells, MSC, ESC), or cell lines used in the production of viral vaccines (vero, MRC-5, BHK, etc) is desirable.
EOE
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