Lab-Gardini - Post

The Wistar Institute - Philadelphia, PA3.9

30+ days ago
Two postdoctoral positions in epigenomics are available in the laboratory of Dr. Alessandro Gardini at The Wistar Institute. The Gardini lab investigates how epigenetic regulators coordinate cell fate commitment in hematopoiesis (Mol Cell. 2018 Jul 5;71(1):103-116). We employ cutting edge functional genomics, biochemistry and proteomics to dissect the enhancer-promoter circuitry that regulates cell commitment (www.wistar.org/our-scientists/alessandro-gardini).

Molecular biology/biochemistry graduates, motivated to conduct research on the fundamental mechanisms of transcriptional regulation, are encouraged to apply. Computational biologists are also encouraged to apply. Those interested, please email a CV, contact information for three references, and a short statement of past achievements and research interests to agardini@wistar.org. Applicants can also apply online at www.wistar.org/employment.

Relevant literature: Barbieri et al., 2018. Targeted enhancer activation by a subunit of the Integrator complex. Mol Cell. Trizzino et al., 2018. The tumor suppressor ARID1A controls global transcription via pausing of RNAPII. Cell Reports. Lai, Gardini et al., 2015. Integrator mediates the biogenesis of enhancer RNAs. Nature. Gardini et al., 2014. The many faces of long noncoding RNAs. FEBS Journal.

We offer competitive salary and excellent benefit package.

The Wistar Institute is located in the University City area of Philadelphia, in the heart of the University of Pennsylvania Campus. Wistar provides resources to its faculty and staff that enable them to conduct cutting edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities. Research discoveries conducted at Wistar have led to the development of vaccines; the identification of genes associated with cancers; and the development of many other significant research technologies and tools.

For more information about The Wistar Institute visit our website at www.wistar.org.