Postdoctoral Associate - Electrophysiology

Broad Institute - Cambridge, MA4.0

Full-timeEstimated: $52,000 - $69,000 a year
Group Description

Research in Stanley Center at Broad Institute aims to reveal the genetic, molecular, cellular and circuitry underpinnings of psychiatric disorders, and eventually to develop novel effective treatments. A postdoctoral position is available to study the synapse and neural circuit mechanisms of psychiatric disorders.

Brief Summary

We seek candidates who are interested in using electrophysiology, optogenetics, viral-mediated genetic manipulation, calcium imaging and behavioral approaches to investigate the neural mechanisms of psychiatric disorders. The successful candidate will work directly with an electrophysiology group in the Department of Neurobiology and Model System at Stanley Center. Individuals with excellent past record of research achievement in in vitro electrophysiology training background, in particular synaptic and circuitry physiology studies, are encouraged to apply. The candidates are expected to perform extensive whole-cell patch-clamp recordings in acute brain slices, iPSCs/ES-based cells and primary cultured neurons. Excellent technical optimization and problem-solving skills will be required. Experience with optogenetic approaches, rodent genetics and behavioral tests are desirable. Experience with programming (MATLAB) is a plus.

Key Responsibilities/Essential Functions

  • Implement and develop in vitro electrophysiological protocols and assays
  • Interact and coordinate with collaborators as required
  • Publish scholarly reports and present at scientific conferences
  • Participate within a team of scientists to foster a culture of scientific discourse and excellence
  • Other related tasks as need
  • Ph.D. in Neuroscience, Neurobiology, Cell biology or related field. Prior postdoctoral experience in not an essential.
  • Demonstrated technical proficiency in in vitro electrophysiological techniques (such as whole-cell patch clamp recordings and field potential recordings).
  • Embracing technical challenges and having excellent capability of trouble shooting.
  • Outstanding personal initiative and communication skills.
  • Must work well in a team environment.
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