Scientist I, DMPK

AbbVie - Lake County, IL

Full-time
AbbVie is seeking a highly motivated Associate Scientist to join our Drug Metabolism and Pharmacokinetics team in North Chicago. In this exciting role, you will be expected contribute to the success of drug candidates through phases of drug discovery and development.

The ideal candidate will have a strong background quantitative laboratory methods and mammalian cell culture and possess ability to generate precise, reliable and reproducible data in a timely manner. Demonstrate strong data interpretation skills, ability to troubleshoot experiments and instrumentation, ability to learn and understand new experimental techniques and be able to place data in proper scientific context by consulting and citing relevant literature. Independently design and conduct critical experiments that further project goals. Implement and may innovate new experimental protocols/techniques. Independently schedule and prioritize workload to manage several tasks simultaneously. Identify and utilize resources outside of own group. Anticipate and adapt to experimental variability. Contribute key data to internal/external reports, documents and publications. Teach methods to others and make time to help other groups/projects with insight and know-how. Enhance performance through cooperation with groups outside project. Contribute key data to publications/reports/posters for external meetings as appropriate. Communicate and defend experimental strategies and results. Prepare written and oral reports of work.

Applicants having significant experience in drug metabolism, pharmacokinetics or hepatocyte biology principles is desirable. The position will involve the conduct of routine and non-routine assays. Present data clearly and thoroughly in both one-on-one and group meetings with clear and precise graphs/charts/ tables. Provide written summary reports as appropriate. Learn and share knowledge with colleagues and participate in internal and potentially external poster presentation opportunities.

Core responsibilities include:
Conducting routine and non-routine ADME assays, generating high quality, reproducible, impactful data that enables decision making.

Writing and reviewing reports suitable for regulatory agency submission

Analyze and critique results, noting significant deviations.

Troubleshoot experiments and instrumentation.

Place data in proper scientific context by consulting and citing relevant literature.

Independently design and conduct critical experiments that further project goals.

Bachelor’s Degree or equivalent education with 5+ years of experience, OR Master’s Degree or equivalent education with 2+ years of experience.
Theoretical and practical knowledge to carry out the job functions.
Necessary skills include: Pipetting, cell culture, quantitative analysis. Effective oral and written communication skills. Experience in primary cell culture (e.g. hepatocytes), radioisotope work, electronic lab notebooks, would be advantageous.