Program Manager

Jounce Therapeutics - Cambridge, MA

Company Summary
Jounce Therapeutics, Inc. is a clinical-stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors and provide long lasting benefits to patients. Through the use of its Translational Science Platform, Jounce first focuses on specific cell types within the human tumor microenvironment (TME) to prioritize targets, and then identifies related biomarkers designed to match the right immunotherapy to the right patient. Jounce has three development stage programs: its two clinical product candidates, JTX-2011, a monoclonal antibody that binds to and activates ICOS, and JTX-4014, a monoclonal antibody that binds to PD-1 to be used in combination with its pipeline of future product candidates, and JTX-8064, a monoclonal antibody that binds to Leukocyte Immunoglobulin Like Receptor B2 (LILRB2) that is currently in the IND-enabling phase. For more information, please visit

Role / Responsibilities
We are seeking an experienced leader for Jounce immunotherapy development programs. The ideal candidate will have a strong scientific background with experience developing oncology biologics. In collaboration with the Program Leader, you will work with Jounce’s cross-functional teams to drive scientific ideas derived from our groundbreaking translational science platform into new medicines to treat serious unmet medical needs. This role reports to the Vice President, Program and Portfolio Strategy.

Job responsibilities

Proactively define (with cross-functional development team) program strategy, goals, decision points, investments and areas of risk and associated mitigations.
Ensure roles and responsibilities are well-understood to maximize forward progress while maintaining alignment between and across functions
Drive execution of program plan while providing visibility to progress versus timeline & changes to risk profile; communicate program status and issues to key stakeholders and senior management.
Facilitate collaborative decision-making discussions with senior leaders and alliance partners
Establish and maintain detailed electronic integrated program plans with input from all functions; Define robust scenario planning capability for evaluation of alternatives
Maintain visibility and operational oversight of resource planning and cost vs budget
Facilitate establishment of program goals and track their execution to deliver on overall corporate
Lead efforts to further develop the program management function in accordance with the needs of the business
Supervise, mentor, and develop junior program management staff as the portfolio grows
Encourage and demonstrate true Jounce spirit of collaboration and fun throughout the organization
Bachelors degree in a scientific discipline w/10 yrs experience or Master’s Degree w/7 yrs experience in pharmaceutical development. 5 years experience in pharmaceutical project or program management.
Desire and demonstrated ability to perform at both a strategic level and in a hands-on capacity; able to drive strategic decision-making.
A thorough understanding of the drug development process and working knowledge of the essential activities for all key functional areas.
Early (phase I & II) clinical trial experience required; late stage (pivotal) clinical trial experience desired.
Strong leadership skills with the ability to inspire people to action through their influence.
Highly flexible, with an aptitude to adjust to new information and translate into options and actions for others
Expert in project management tool suite (Microsoft Project, Visio, Word, Excel, PowerPoint)
Outstanding interpersonal, oral, and written communication skills.
To apply, please visit

Jounce Therapeutics is an equal opportunity employer and does not discriminate in its employment decisions on the basis of race, color, national origin, age, physical or mental disability, marital status, religion, creed, sex, or political beliefs. We offer a competitive salary and benefits package. All applicants should be legally entitled to work for any employer in the U.S.

To apply, please visit