The job’s main responsibility is to collaborate with biologists, bioinformaticians, and clinicians to design, validate, and maintain bioinformatics pipelines and applications.
Position Duties and Responsibilities:
Provide bioinformatics support to R&D by analyzing and interpreting NGS data
Validate new assays and clinical product development
Perform NGS data analysis and QA/QC platform
Provide trouble shooting and improvement for bioinformatics pipeline and applications for clinical tests
Develop new methods and maintain bioinformatics pipelines
Work with statisticians in validation of new methods, including data collection and analysis algorithms
Develop features/tools assisting clinical and genetic analysis
MS degree in bioinformatics, computational biology, biology and computer science, or related discipline. PhD is preferred.
Familiar with molecular biology, biological pathways, and genomics
Strong knowledge of current theories and principals of bioinformatics and computational biology
Proficiency in the use of bioinformatics software and packages (eg. GATK, BCFtools, BLAST, BWA, PLINK, etc), and publicly available genetics databases (eg. ExAC, ESP, ClinVar, GenBank, Ensemble, KEGG, HGMD, OMIM, etc.).
Proficiency with Python, Perl, R, bash, C/C++, or java in Linux/Unix environment
Strong skills in the application of statistical analytical methods in genetic data analysis
Experience in data modeling, SQL query, AI and machine learning is plus
Experience in Cloud Computing
Excellent oral and written communication skills
Ability to work within a team, among cross-departments, and as an independent contributor, requiring minimal supervision
Experiences in using high performance computing and storage systems
Experience in Illumina sequencing data and bioinformatics Next Generation Sequencing pipelines
Ambry Genetics Corporation is a CAP-accredited and CLIA-licensed molecular genetics laboratory based in Aliso Viejo, California. We are a genetics-based healthcare company that is dedicated to open scientific exchange so we can work together to understand and treat all human disease faster.
At Ambry, everyone is welcome. A career at Ambry Genetics is a chance to be part of a dynamic company that aims to improve health by understanding the relationships between genetics and human disease. We earned our reputation as industry leaders by responsibly introducing cutting-edge genetic testing solutions and continually sharing what we learn with the global scientific community. We also support those with genetic conditions through the Mauli Ola Foundation and other nonprofit organizations. At Ambry you will be learning, challenging yourself, and having fun while collaborating with teammates through the open exchange of ideas.
Employees at Ambry Genetics have many perks, including an onsite café with complimentary smoothies and infused waters! We also offer access to gym memberships, onsite food trucks, “Lunch and Learns,” Pajama Days, Chili Cook-Offs and more. Our outstanding benefits program includes medical, dental, vision, 401k, FSA, generous paid time off (PTO) program, and flexible scheduling as determined appropriate. Ambry Genetics is an Equal Opportunity Employer (EOE) and we maintain a drug-free work environment.
Ambry Genetics is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
Masters or better in Bioinformatics or related field
PHD or better in Bioinformatics or related field