Malaria Liver Stage Screening Support Technician

General Dynamics Information Technology - Silver Spring, MD3.8

Full-timeEstimated: $58,000 - $74,000 a year
GDIT is seeking a Malaria Liver Stage Screening Support Technician to support the mission of the Experimental Therapeutics (ET) Branch of the Walter Reed Army Institute of Research (WRAIR). The mission of the WRAIR Branch of Experimental Therapeutics is to discover and develop new pharmaceutical agents to protect military members from death, disease, and injury. The Branch is the nation’s primary developer of new drugs to prevent and/or treat malaria and leishmaniasis. Collectively, ET engages in drug discovery, drug efficacy and mechanism evaluation, and formal preclinical and clinical development. This position supports the Department of Drug Discovery by providing in vitro liver stage malaria and toxicity screen support. Specific responsiiblities include:

Perform in vitro Inhibition of Liver Stage Development Assay (ILSDA).
Manage the isolation of malaria sporozoites from mosquito salivary glands.
Assist in optimizing an in vitro screen for assessing drug effects on liver stage of malaria.
Execute in vitro assay for cell toxicity (in HepG2 and macrophages Raw264.7 cells).
Provide malaria sporozoites to support the in vivo mouse malaria model systems.
Analyze and summarize experimental data for reports and presentations and publications.
Maintain a safe working environment and adhere to applicable safety regulations.
Attend and present at relevant national scientific conferences, if required by Department of Discovery.


MS in Microbiology, biomedical field or related field strongly preferred


5+ years experience

Able to perform and maintain all aspects of an in vitro liver-stage antimalarial compound screen and a toxicity compound screen.
Able to analyze and summarize experimental data for reports, publications, and presentations and to compile the data into a suitable format for upload into the LIMS.
Able to provide malaria sporozoites to support in vivo studies.

For more than 50 years, General Dynamics Information Technology has served as a trusted provider of information technology, systems engineering, training and professional services to customers across federal, state, and local governments, and in the commercial sector. Over 40,000 GDIT professionals deliver enterprise solutions, manage mission-critical IT programs and provide mission support services worldwide. GDIT is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status, or any other protected class.