Principal Scientist Chem Bio

Merck USA - West Point, PA4.1

30+ days agoFull-time
Requisition ID: PHA001470

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.

The Chemical Biology group is seeking a pharmacologist with experience leading small molecule phenotypic screening projects. Experience interrogating compound effects on phenotypes of interest is required. A successful candidate will be able to design cell-based experiments using genetic and pharmacological manipulation of pathways and proteins in relevant systems to validate novel targets and characterize molecular mode of action of tool compounds. Preference will be given to a candidate with a chemical biology background, high content imaging and/or 3D cellular culture and assay development experience. The successful applicant will have experience managing scientists, a track record of achievement leading projects, and independently designing and executing experiments. A Ph.D. in Biology or equivalent with 8 or more years of industrial experience is required.


Education Minimum Requirement: :

Ph.D. in Biology or related field.

Required Experience and Skills:
  • 8 years of industry experience
  • Experience working with assay development
  • People Management/Supervisor experience
Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life.

If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to

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Visa sponsorship is not available for this position.