Under minimal supervision, maintain a high through-put diagnostic laboratory that focuses on testing and optimizing, developing and implementing family/genus level viral diagnostics for the USAID-funded PREDICT project, receiving and testing samples from multiple field teams globally. Process and perform laboratory diagnostics, track specimens, results, and interpret diagnostic data. Trouble-shoot and correct diagnostic assay performance, develop and design new technologies and oversee daily laboratory functions. Assist with managing day-to-day activities of the Davis laboratory. Assist graduate students and post doctoral fellows with their research. Supervise and mentor junior laboratory staff (laboratory assistants) and undergraduate and veterinary volunteers and assistants. Support capacity building efforts in East and West Africa and Asia for PREDICT's collaborating laboratories, including providing training for visiting staff at UC Davis, traveling to East and West Africa and Asia to provide in-person trainings in collaborating labs, provide daily and weekly support and interpretation of results and trouble shooting of assays to in-country laboratory teams through email and skype meetings. Assist in-country teams to implement safety programs to safely handle and test PREDICT samples.. Assist in-country laboratories with providing support on implementing lab protocols and interpreting results. Perform sequence analysis and interpretations including nucleotide and amino acid alignments and phylogenetic analyses. Edit and prepare sequences generated for the PREDICT project (>8,000 sequences) for Genbank submission with the appropriate metadata. Research literature, interpret data and support preparation of data for result reports, publication, presentations and grant submissions.
Lift/move equipment and chemicals weighing up to 50 lbs.
Wear protective clothing for extended periods of time, use of biological safety cabinet and contact with biohazardous materials.
Move from room to room, standing or sitting for extended periods of time.
Travel internationally, sitting on airplanes for up to 15 hours at a time.
Valid California driver's license.
Work schedule is subject to change, but mainly during primary business hours. Occasionally work a flexible schedule including evenings and nights. May also require occasional field work.
This position is subject to Medical Surveillance procedures and review in accordance with Federal and State Laws and Regulations and University Policy.
Occasional travel to a foreign country for weeks at a time to provide training, in a changing and challenging environment.
UC Davis is a smoke and tobacco free campus effective January 1, 2014. Smoking, the use of smokeless tobacco products, and the use of unregulated nicotine products (e-cigarettes) will be strictly prohibited on any UC Davis owned or leased property, indoors and outdoors, including parking lots and residential space.
Background Check Required:
This position is a critical position and subject to a background check. Employment is contingent upon successful completion of background investigation including criminal history and identity checks.
Hands-on experience performing molecular and serologic assays including PCR, RT-PCR, real-time PCR, ELISA, serum neutralization, and mammalian cell culture, library preparation for high through-put sequencing, co-immunoprecipitation assays.
Specialized knowledge and technical training in molecular techniques, diagnostics, and reagents typically obtained with education at the Master's level, or with a combination of education and experience.
Experience working with animal tissues including swabs, blood, tissue, serum.
Experience with, knowledge and understanding of, and skills in, molecular biology, genetics, virology and immunology to understand, and follow published or documented techniques and procedures.
Skills to interpret data, recognize irregular or invalid results, troubleshoot assays and correct assay performance failures.
Experience communicating complicated scientific research to lay audiences.
Experience with and skills in overseeing the work of junior laboratory staff, including planning and reviewing work assignments and giving assistance in the solution of work problems.
Experience with and skills in instructing and training others in laboratory procedures, especially in foreign countries where the use of English is limited.
Knowledge and understanding of international development and health issues.
Experience in and skills with the design and development of new assays and laboratory techniques.
Listening skills to analyze issues and present information and recommendations concisely.
Interpersonal skill to work effectively with people with diverse cultural backgrounds and education levels.
Experience with electronic record keeping systems for data analysis and interpretation, including FileMaker Pro, Geneious, Vector NTI, Primer Express, and Gel documentation equipment.
Knowledge of, and experience with, PREDICT protocols and laboratory techniques.
Knowledge of and skills to adhere to diagnostic lab quality control procedures and standards.
Experience providing training and conducting research responsibilities in an international setting.
Basic computer skills including experience using Word, Excel, FileMaker.
Knowledge of laboratory safety and documentation.
Fluent in french.