Scientist I DMPK

Takeda Pharmaceuticals - Boston, MA3.8

Full-timeEstimated: $61,000 - $86,000 a year
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Job Description
Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Scientist I DMPK in our Cambridge office.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Futureto people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.

The new hire will be part of the bioanalytical group within the global DMPK department working at 125 Binney St, Cambridge, MA. She/he will focus on preclinical stage bioanalytical support of PK/CK, PD biomarker, immunogenicity testing for the early discovery support for the Rare Disease Drug Discovery Unit (RD DDU). The individual is expected to perform innovative method development for large molecule quantifications, effectively trouble-shoot bioanalytical assay related issues, and actively identify/adopt/develop new technologies to meet the ever-changing needs of projects together with key stakeholders such as DMPK project representatives, Drug Discovery Units (DDUs), DSRE and QTS groups. Hands on experience in LBA-based assay, hardware and software skills in setting up quantitative PCR would be a plus.

Serve as the lead bioanalytical scientist on projects or DMPK bioanalytical representative to interact with DMPK and Rare Disease DDU project members.
Support early drug discovery and translational research by providing high quality bioanalytical support with a focus on large molecule quantification using LBA, mass spectrometry, and other pertinent platform technologies. Communicate with internal stakeholders regarding the assay needs, progress updates, and DMPK bioanalytical deliverables.
Apply independent creative thinking and lab work in seeking solutions for moving projects forward. Design, test, and implement new methodologies and processes that contribute to the research goals of the group/department. Mentor and guide junior research associate scientists.
Summarize and present the experimental result in the cross-functional project team, BA group and DMPK department meetings. Proactively seek for opportunities for updating professional skills through training or participating in conferences. Highly encouraged to contribute to external presentations and publications.
Provide scientific monitoring and guidance of external resources (CRO) for the method transfer, development, trouble shooting, qualification, validation and report to support drug discovery and nonclinical development programs. Assist in managing CRO sample and data flow logistics as necessary.
Coordinate the critical reagent supply and maintain the inventory for the bioanalytical assay.

The applicant must have Master of Science (or higher) degree in molecular biology, biochemistry, biotechnology, pharmaceutical sciences or other related fields with a minimum of 10 years of relevant industry research experience.
Hands-on experience and deep knowledge in the bioanalytical and biomarker assay development by MSD and Gyrolab. Familiar with diverse lab equipment for large molecule bioanalytical assays, reagent supplies and characterization.
Experience in PCR method qualification, cell-based assay development such as NAb assay is plus.
Must be detail oriented with excellent inter-personal skills and oral and written communication capabilities for working in a dynamic team environment and mentoring the junior scientist.
Good understanding of relevant regulatory requirement and adaptability for ever-evolving bioanalytical techniques.

401(k) with company match and Annual Retirement Contribution Plan
Tuition reimbursement Company match of charitable contributions
Health & Wellness programs including onsite flu shots and health screenings
Generous time off for vacation and the option to purchase additional vacation days
Community Outreach Programs
Empowering Our People to Shine

Discover more at

No Phone Calls or Recruiters Please.


Boston, MA

Worker Type

Worker Sub-Type

Time Type
Full time

Job ID R0013513