Full Job Description
We are looking for a Research Associate, Scientist for the Antibody Development Group with solid hands-on experience in protein purification, and process development. He/she will play a key role in producing high quality proteins to support in vitro assays and in vivo efficacy studies. He/She will contribute to develop processes for QLB pipeline molecules. The successful candidate is expected to be energetic self-starter, adept at multi-tasking, with critical problem-solving abilities.
Chromatography purification of recombination proteins, and some analytic assays for characterization of the recombinant antibodies/proteins.
Participate in downstream process development for antibodies and bispecifics
Carry out other responsibilities related to supplying and maintaining QLB inventory of produced proteins.
Write SOPs, summarize and present data internally within a multidisciplinary team environment; Other responsibilities as assigned.
Bachelor, MS in protein biochemistry, bioengineering, chemical engineering or relevant discipline, with 2+ years’ experience in biotech or biopharmaceutical industry.
Demonstrated experience with protein purification by standard chromatography methods (Affinity, ion exchange, hydrophobic interaction, SEC) as well as fluency with the theoretical concepts underlying protein purification.
Extensive hands-on experience using chromatography equipment such as Akta Explorer, Akta Pure or Akta Avant, and column packing.
Demonstrated experience with analytics and characterization of proteins and antibodies (SDS-PAGE, Western Blot, residual Host Cell Proteins, residual DNA, HPLC).
Experience with Tangential Flow Filtration (TFF) is preferred.
Experience with designing and performing DOEs is a plus.
Experience with biologics drug development is a plus.
Ability to work independently or with limited direct supervision.
Attention to detail, accurate and timely documentation of data, and effectively communicate results.
Enjoys working in a fast-paced, team-oriented, multidisciplinary environment.
We offer competitive compensation package, for additional information, please contact: email@example.com