Host-Microbe Informatics Post-Doctoral Fellow

GlaxoSmithKline - Upper Providence, PA (30+ days ago)4.2


Your Responsibilities:
.
This Early Talent postdoctoral fellowship (3 year) with the Computational Biology Department involves working with multiple therapy area teams on the interactions between the microbiome, pathogens and human host immunity. The roles of both beneficial and pathogenic microbes on human host pathways are being increasingly linked to the occurrences of many chronic and infectious diseases. With the rapid expansion of genomics and drug screening platforms, there is a significant opportunity for data-mining these resources to identify novel human gene targets modulated by microbial metabolites and peptides for the treatment of infectious and inflammatory diseases. The successful candidate will participate in multidisciplinary drug discovery teams by contributing novel genomics and chemistry analyses (chemogenomics) on human host-microbe interactions; provide expert knowledge to scientific teams; make presentations to internal and external scientific conferences and; be the lead author of manuscripts submitted to high impact, scientific peer-reviewed journals. This is an excellent opportunity for those interested in applying their chemoinformatics and bioinformatics skills to translational and transformative medicine projects in a large pharmaceutical R&D organization.
*LI-GSK

Why You?

Basic Qualifications
• Recent PhD in bioinformatics / computational science / biomedical engineering/ biological sciences or equivalent research experience.
• Demonstrated skills to programmatically analyse complex biomedical and compound assay datasets.
• Experience in the analysis of microbiome and human genomic datasets especially from Next Generation DNA sequencing platforms.
• Demonstrated ability to use chemoinformatics approaches to solve problems in chemical biology, drug discovery or related fields.
• Expertise in computer languages such as Python, Perl, R Statistics and Java.
• Knowledge of Machine Learning methods are an advantage.
• Good verbal and written communication skills and ability to work well with multi-disciplinary teams.
• Evidence of publication authorship in peer reviewed journals.

Preferred qualifications:
N/A

Why GSK?:
In GlaxoSmithKline R&D (http://www.gsk.com/research.html), computational biologists have a broad and essential role in drug discovery through the integrative analysis of internal and external biomedical data, combining strong computational skills with biological insight. Our work results in real impacts on new therapeutic approaches to highly important diseases of unmet medical need

Contact information:
You may apply for this position online by selecting the Apply now button.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK HR Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit GSK’s Transparency Reporting For the Record site.