Senior Principal Scientist - MSAT (Manufacturing, Science and Technology)

Lonza - United States3.6

At Lonza, we invest in great people. We encourage our employees to challenge themselves and we offer an environment that fosters creativity and success. Headquartered in Basel, Switzerland, we operate production, R&D, and business sites around the world, including Europe, North America, and Asia.

Our vision:
We strive to be the leading supplier using science and technology to improve the quality of life.

Our mission:
We work with passion, using advanced technologies, to transform life science into new possibilities for our customers.

Do you want to help us as we shape the future of this great organization?

Job Description Summary
Senior Principal Scientist - MSAT (Manufacturing, Science and Technology)

Be part of something life changing.

Lonza MSAT. The beating heart of a living business.

Lonza Manufacturing, Science and Technology is the beating heart of our business.

We are a team of experienced and passionate individuals who use ground-breaking solutions to redefine perspectives. We focus on innovation to evolve the link between Lonza and the lives we save. If you’d like to work in a hugely varied role in an exciting area of our growing business, then progress your career as an MSAT Scientist or Engineer.

MSAT plays a critical role in the successful transition of innovative technology and biologics process technical transfer oversight from laboratory to cGMP manufacturing scales providing our customers with range of services in the realization of the next generation of therapeutic molecules with one mission “making tomorrows medicines today”!

The technical diversity, strong teamwork and cross functional collaboration in a fast paced working environment makes the MSAT roles dynamic, exciting and rewarding offering excellent personal and professional development within the function and across the Lonza global network.

The roles:
Due to the significant growth and expansion of Lonza’s Slough manufacturing operations and Lonza’s global center of excellence in process development, we have a number of open positions for Senior Principal Scientists to join the Manufacturing, Science and Technology (MSAT) organization. These positions will lead the technical transfer of multiple concurrent complex manufacturing processes (either USP and/or DSP) using a defined structured approach and be the technical expertise between Process Development GMP manufacturing. The role is accountable to ensure that a robust manufacturing process is transfered according to both internal and external customer needs.

The Senior Principal Scientist will be a recognized process expert in USP or DSP operatiions. The individual will provide detailed technical support via multiple customer facing project teams to deliver existing but also novel technology advancement, perform complex technical data analysis and deliver the required complex technical process documentation in collaboration, negotiation and discussion with external customers, team SME’s and internal stakeholders as required.

This role will have an established internal network and have influence and credibility across operations in area of expertise and with MSAT team management.

To represent MSAT within within multiple customer facing product project teams using a both standard and new methodology/procedure to successfully transfer USP and/or DSP cGMP biologics manufacturing processes.
To be accountable for the introduction and support of qualification of new process technologies into cGMP manufacturing, whilst managing technical risks associated with process transfer, leading cross functional teams to ensure relevant transfer and communication of critical process and technical information such that successful outcomes are achieved as agreed with customers.
To pro-actively communicate effectively negotiate, collaborate and demonstrate technical influence over the customer, via both face to face meeting and telecoms driving problem resolution and offer successful technical outcomes
To be accountable for independent on plant technical support, process monitoring and complex data analysis using experience to anticipate issues before they become critical.
To lead associated improvement activities leading cross-functional teams to successfully implement according to customer and business needs.
To use technical influence and knowledge in project teams to ensure delivery of project timelines according to customer needs
To proactively anticipate, evaluate and resolve technical challenges within area of expertise
To be self-managed in resolving gaps in unit operations through batch reviews and applied continual process learning/knowledge capture.
To be aware of external biopharmaceutical manufacturing technology advancements, understand and introduce new technologies and how they may be applicable to process innovation, cost or yield improvement.
To act as coach/mentor to other team members and also cross functionally and SME and share knowledge in certain aspects of process operations

What we need you to have:
MSc/PhD in science related disciplines
Mammalian or microbial background for drug substance manufacturing support experience
Extensive experience in a drug substance GMP operations
Strong knowledge in process development and/or a manufacturing operations validation background.
Be a recognized expert in field USP and/or DSP drug substance operations from working in the filed for an extensive period of time.
Have a successful technical transfer expertise gained from a drug substance-manufacturing environment.
Have demonstrable experience working in cross-functional project management with ability to multi task, prioritize and be an effective decision maker influential.
Have a deep understanding of manufacturing process as a whole e.g. Supply chain, analytical, QA, QC.
Strong interpersonal skills are required with ability to work cross functionally with internal and external customers on a daily basis.
Applications opening date: 02/01/2019

Application closing date: 02/02/2019

Salary : competitive

We look forward to receiving your application!

Lonza. The place to Go, Stay and Grow.