The mission of the Department of Genitourinary Medical Oncology is to reduce the morbidity and mortality of genitourinary cancers for the benefit of our patients and for future generations.
Independently, performs and assists in both in vitro and in vivo animal experiments investigating tumor cell (e.g. prostate) invasion, growth, resistance niches in response to clinical relevant therapeutic strategies (e.g. Rad223) in orthotopic and model niches (e.g. engineered bone and fibrotic); monitors tumor response using immunofluorescence, confocal, and multiphoton microscopies and preclinical imaging techniques; generates reporter cell lines and performs 3D in vitro experiments to validate and guide in vivo, preclinical animal experiments; has biology background and expertise in imaging analysis with some application of molecular biology and protein biochemistry of cells and tissue samples.
Knowledge in the following procedures are required:
Intermediate immunofluorescence, confocal, epifluorescence microscopy and image analysis (Fiji/ImageJ or other) skills
Multiphoton microscopy for immunofluorescence and in vivo imaging in skin and mammary window models, and in other organs, as applicable
Cell/tissue culture of primary cells (e.g. stem cells) and cancer cell lines, 3D cultures and polymer scaffolds for tissue engineered tumor models (e.g. engineered bone and other)
Advanced tissue clearing and staining techniques for hard and soft tissues (e.g. skin and bone)
Preclinical imaging (e.g. microCT, X-Ray, IVIS, Optical whole-body imaging)
Molecular biology (vector cloning, DNA/RNA purification, transfections, lentivirus production, lentiviral transductions)
Generation of modified/reporter cell lines and cryostorage
Histological procedures (Fixation, Slicing, Staining, Sample storage)
Microfabrication of polymeric fibers and application for in vitro cell culture
Flow cytometry (FACS) and analysis
Acquire and develop new techniques:
- Must possess flexibility and have the ability to learn and establish novel techniques and protocols for new research lines.
- Independently reads and understands scientific literature for application to ongoing research.
Proper and accurate maintenance of laboratory notebook (written or electronic)
Manage, record, update inventories (digital and written databases)
Order material for the laboratory in a timely fashion
Must work with other lab members to ensure the consistent flow of work, necessary materials and reagents
Perform laboratory tasks assigned by supervisor/lab manager
Collaborate and conduct experiments/work on other lab projects when necessary
For incoming packages:
ascertain contents, store at appropriate location, file information sheets and notify relevant lab personnel/principal investigator.
Must be able to learn and use software related to data acquisition, analysis and presentation
Other duties as assigned.
Bachelor's degree with major course works in one of the basic sciences.
Two years experience in scientific or experimental research work. No experience required with preferred degree.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
exempt and not eligible for overtime pay
US Dollar (USD) 36,000
US Dollar (USD) 44,500
Maximum Salary :
US Dollar (USD) 54,000