Full Job Description
This role works out of our Headquarters in Redwood City, CA.
Due to the Covid 19 Pandemic Guardant Health has temporarily classified this role as ‘partial working from home status’, meaning as duties apply this role the person will be expected onsite a few days a week.
We will fully return onsite at HQ when it is determined safe to do so.
Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform is designed to leverage our capabilities in technology, clinical development, regulatory and reimbursement to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs.
In pursuit of our goal to manage cancer across all stages of the disease, Guardant Health has launched two liquid biopsy-based tests, Guardant360 and GuardantOMNI, for advanced stage cancer patients, and is developing programs for recurrence and early detection, called Project LUNAR. Since its launch in 2014, Guardant360 has been used by more than 5,000 oncologists, over 40 biopharmaceutical companies and all 27 of the National Comprehensive Cancer Network centers.
In this role, you’ll be responsible for leading a team that automates and scales complex workflows and implements processes for a state-of-the-art sequencing lab. You will support the development of all parts of a state-of-the-art automated assay workflow.
You will be directly responsible for leading a small team of automation engineers and leading all aspects of automation development from concept, requirements definition, and automated assay development, including liquid handling, optimization, error handling, and validation. You will leverage an understanding of molecular biology to troubleshoot analytical and preparative processes on automation platforms.
The successful candidate will apply engineering skills and scientific methods to improve the scalability and reliability of Guardant Health’s automated assay workflows.
You must be collaborative and able to lead cross-functional teams working across a variety of projects effectively. These cross-functional teams will develop, optimize, and implement robust, scalable solutions for Guardant Health’s sample processing workflows with attention to improving efficiency, throughput, and quality. You will supervise and develop the capabilities of automation engineers. Furthermore, you have a strong organizational capacity to plan and lead the day to day execution of engineers within the automation engineering department.
Essential Duties and Responsibilities:
Manage a team of engineers and technicians. Includes having oversight over the hiring, development, and potential termination of team members.
Manage automation and assay development projects from concept to post-implementation support.
Analyze workflows, identify bottlenecks, and develop solutions to improve efficiency, throughput, cost, and quality
Lead or contribute to the innovation of current and new assays workflows, technologies and processes
Lead or contribute to the design, development, optimization, and implementation of automated liquid handling processes, systems, and streamlined workflows using DOE methodologies
Drive collection of process requirements from cross-functional stakeholders
Draft development plans, test plans, and associated procedures for automated workflows.
Program robotic liquid handling workstations and integrated robotic systems
Develop instrument integration with a Laboratory Information Management System
Are you an engineer with a proven track record of automating and scaling? You’ve established yourself as a manager or supervisor previously. You’re eager to participate in the development of high growth, fast-paced startup? An interdisciplinary background in molecular biology, lab automation, and programming is required.
The ideal candidate will have prior, demonstrated experience designing, developing, testing, implementing, and supporting automated sample-processing workflows using a requirements-driven approach in a clinical laboratory or other molecular biology-based laboratory settings. Will leverage an understanding of molecular biology and biochemistry to troubleshoot analytical and preparative processes. The successful candidate will apply scientific methods and engineering skills to improve the scalability of Guardant Health’s sample processing workflows.
You also have:
BS degree in engineering or science, preferably in molecular biology, genetics or biochemistry, bioengineering, chemical engineering, or a closely-related discipline and 8+ years of related experience. An MS with 6+ years of relevant work experience or a Ph.D. with 5+ years of relevant work experience.
Experience managing or supervising a small group of employees.
Background working in regulated laboratory environments (CLIA, IVD)
Highly skilled in streamlining workflows and developing automated laboratory processes and instrumentation systems, including collecting and documenting requirements, developing concepts, design, testing/validation, implementing, and training
Experience with operating and programming liquid handling robotics platforms (Hamilton, TECAN, Beckman, Agilent)
Highly skilled with standard molecular biology techniques such as nucleic acid isolation, purification, and quantitation, bioanalyzer, DNA/RNA quantitation, qPCR or next-generation sequencing
All your information will be kept confidential according to EEO guidelines.
Employee may be required to lift routine office supplies up to 20 lbs and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposed to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.
Please visit our career page at: http://www.guardanthealth.com/jobs/