The successful candidate is a skilled scientist with strong expertise in classical and novel molecular biology techniques and who is experienced in utilizing automation systems to assist with laboratory workflows.
The scientist will work on supporting advancement of drug targets in the field of cardio-metabolic diseases including target validation, mechanistic and functional assay development and molecule evaluation. This position will support ongoing efforts to automate manual workflows and processes onto a semi-automated/fully automated robotics platform.
As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.
Duties & Responsibilities:
Conducts scientific research utilizing molecular biology techniques, interprets experimental results and integrates them with project objectives
Responsible for technical leadership of automation systems relevant to molecular biology techniques
Collaborates with peers and cross functional teams and provides technical guidance in areas of expertise
Effectively organizes and communicate results and findings internally within and across departments as well as externally
Required Skills and Abilities:
Experience with nucleic acid sample preparation technologies (e.g. primer design, RT-qPCR etc.) from human tissue and cell lines – FFPE preparations a plus
Knowledge in plasmid construct design, agarose gel electrophoresis, RNA/DNA purification, sequencing and sequence analysis
Proven experience in modern molecular biology techniques (e.g. PCR optimization, troubleshooting) and related primary data analysis
Experience in running automation and high throughput instrumentation including liquid handlers (Beckman Biomek) and library preparations
Agility in prioritizing efforts and ability to multi-task to deliver on commitments
Ability to work in a fast-paced collaborative environment while maintaining a high level of attention to detail
Desired Skills and Abilities:
Familiarity with generating AAV, lentiviral, minicircle and other gene delivery vectors
Ability to manipulate cells using plasmid and siRNA transfection and viral transduction
ddPCR™, Next Generation Sequencing (Illumina® HiSeq, NextSeq) and single cell microfluidic platforms (Fluidigm, 10x Genomics) a plus
Ability to work with Laboratory Information Management System (LIMS)
Scientist III Requirements:
Master’s Degree with 3+ years' experience in related scientific discipline or Bachelor’s Degree with 7+ years' experience in related scientific discipline or equivalent experience in related field
Scientist IV Requirements:
Master’s Degree with 6+ years' experience in related scientific discipline or Bachelor’s Degree with 10+ years' experience in related scientific discipline or equivalent experience in related field
Supplemental technical courses in area of expertise
Ability to operate laboratory equipment with independence
Ability to draft technical reports
Demonstrate written and verbal communication skills
Concise and accurate reporting of technical data and interpretation thereof
Proven problem solving ability
Able to act for supervisor in his/her absence
Appropriate level of understanding of applicable regulations
Must be legally authorized to work in the United States without restriction.
Must be willing to take a drug test and post-offer physical (if required)
Must be 18 years of age or older
Boehringer Ingelheim is a different kind of pharmaceutical company, a privately held company with the ability to have an innovative and long term view. Our focus is on scientific discoveries that improve patients' lives and we equate success as a pharmaceutical company with the steady introduction of truly innovative medicines. Boehringer Ingelheim is the largest privately held pharmaceutical corporation in the world and ranks among the world's 20 leading pharmaceutical corporations. At Boehringer Ingelheim, we are committed to delivering value through innovation. Employees are challenged to take initiative and achieve outstanding results. Ultimately, our culture and drive allows us to maintain one of the highest levels of excellence in our industry. Boehringer Ingelheim, including Boehringer Ingelheim Pharmaceuticals, Inc., Boehringer Ingelheim USA, Boehringer Ingelheim Animal Health USA, Inc., Merial Barceloneta, LLC and Boehringer Ingelheim Fremont, Inc. is an equal opportunity and affirmative action employer committed to a culturally diverse workforce - Minority/Female/Protected Veteran/Person with a Disability. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
Boehringer Ingelheim is firmly committed to ensuring a safe, healthy, productive and efficient work environment for our employees, partners and customers. As part of that commitment, Boehringer Ingelheim conducts pre-employment verifications and drug screenings.
Job - Research & Development
Primary Location - Americas-US-CT-Ridgefield
Organization - US-BI Pharma/BI USA
Schedule - Full-time