Senior Research Technician II

Cherokee Nation Businesses - San Antonio, TX (30+ days ago)3.5

Joint Inflammation Modulation of Trauma Program (JIMoT)

San Antonio, Texas

This is a DoD research effort forcing on applied translational research aimed at reducing mortality and morbidity of severe combat casualty. Traumatic hemorrhage (TH) represents the leading cause of death from severe traumatic injuries in both military and civilian environments. TH accounted for 45-68% of U.S. military deaths in Operation Iraqi Freedom, and 90% of these deaths occurred prior to hospital arrival. Recent clinical and experimental studies have brought increasing evidence for activation of the innate immune system in contributing to the pathogenesis and adverse outcomes.

Our program is primary goal is to identify using animal models of TH and supporting clinical studies, selected immune-inflammatory molecules of therapeutic value to be administered early after injury in a pre-hospital setting. This work requires an expert understanding of molecular biology, protein biochemistry, immunology and medicine. Our Team member have experience in the field of medicine with educational degrees of Ph.D, M.D., M.S., B.S. or extensive experience in their particular technical areas of expertise.

Our client is in need of a Senior Research Technician II to aid in their mission.

General Duties

Prepare equipment for animal experiments.

Maintains laboratory in accord with applicable standards.

Comply with occupational health and safety standards and other applicable regulations and guidelines which may include medical surveillance.

Provides specialized training in new method and procedures as required.

Keeps accurate and complete records of research done in accordance with applicable standards.

Assist with day-to-day activities within the research laboratory, including recommending orders to Government officials and organization of reagents and supplies, assuring proper functioning of essential equipment.

Participate in specific laboratory research projects, and aid laboratory members in research assays.
Assist in post-experiment processing of animal specimens such as frozen tissue blocks for frozen section cut.
Independently plans and executes experiments utilizing animal models of traumatic hemorrhage and blast induced neuro trauma models.
Conduct animal perioperative and postoperative procedures in large and small animal models of traumatic hemorrhage.
Assists in the necropsy, tissue collection, tissue preservation, and carcass disposal of experimental animals.
Cleans, sterilizes, and maintains all instruments and equipment in the surgery area.
Prepares catheters and other devices for use in sterile procedures.
Cleans, sterilizes, and maintains all instruments and equipment in the surgery area.
Prepares catheters and other devices for use in sterile procedures.
Assists with daily calibration of monitoring equipment and analog-to-digital data collection system.


Bachelor's or Master’s degree in science related field
At least 10 years of experience handing animals in a BSL2 environment.
Must hold ALACC accreditation for working with laboratory animals.
A minimum of 5 years of experience in conducting small animal surgeries.
Demonstrated at least 4 years hands on experience working with complement system modulation/inhibition using biological animal models and performing lab assays to determine complement activity/deposition in tissues/organs.
Demonstrated 10 years minimum experience with sterile surgical procedures on large animals.
10 + years of experience in large animal models of traumatic hemorrhage.
Operational knowledge of advanced lab equipment; familiarity with computing equipment to include physiological data acquisition and analysis.
Ability to work independently as well as with a team.

Must be a US citizen

General Experience:
Must have skill and the ability to follows established research protocols

Be knowledgeable of and ability to enrolled in annual required safety training classes.

Must have skill in collects blood samples and determines plasma/serum metabolic changes Assists senior scientists to determine histological changes in tissues.

Skills and ability of collects tissue samples extracted during animal necropsy and prepare them for analysis.

Skilling in prepares in post-experiment processing of animal specimens such as frozen tissue blocks for frozen section cut.

Experience in proper documentation of surgical procedures and IACUC mandated regulatory materials

Skills in assisting with instrumentation, monitoring, surgical preparation, care and observation during recovery, administration of experimental treatments, sample collection, and observation associated with the collection of research data surgical procedures

Ability to do daily calibration of monitoring equipment and analog-to-digital data collection system.

Applicants selected will be subject to a U.S. Government security investigation and must meet eligibility requirements for access to classified information.

Apply online at

Cherokee Nation Technology Solutions provides technical support services and project support personnel to our Government and industry partners. Our highly skilled experts support and supplement the mission, expertise, and skill sets of our clients. Utilizing our customer-intimate approach, we partner with our clients to provide strategic solutions that maximize the use of human and financial resources to ensure that mission-critical projects are completed on time and within budget.

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