- Data Mining
Affymetrix, now part of Thermo Fisher Scientific
Affymetrix seeks a talented bioinformatics scientist to join a multidisciplinary team focused on the development and use of genotyping platforms for research, biobank applications, direct-to-consumer genetic testing, and agri-genomics. The successful candidate will contribute to all aspects of the technology, including data mining, oligonucleotide probe design, algorithm development, and data analysis.
Primary Duties and Responsibilities:
Data mining in Affymetrix’ proprietary database and public database
Genotyping microarray design in collaboration with customers and researchers
Analysis of large datasets, including internal data and customers’ experimental results
Development of algorithms for genotyping, improvement of current and development of new QC metrics, assessing and improving probe performance through novel probe design
Interacts with scientists across the organization
Presents results both internally as well at scientific meetings and conferences
Participates in process and operation improvement opportunities
Responds to internal and external inquiries
Complies with company quality management systems, policies and procedures
Provides mentorship, if applicable
Additional duties/responsibilities according to business needs
PhD in Bioinformatics, Statistical Genetics, or Genome Science with experience in genotyping and/or genetics or equivalent experience
3+ years working experience
Excellent communication skills
Strong initiative and demonstrated ability to take ownership of challenging problems.
Proficiency in R, SQL, and a scripting language such as Python or Perl
Proficiency with statistical tests, linear models, ANOVA, etc
Knowledge of human genotyping imputation considered a strong plus
Experience working with scientist customers or collaborators is a strong plus.
Experience in analysis of microarray data considered a strong plus.
Level of Autonomy and Complexity:
Experienced professional with full comprehension of established principles, theories, concepts to resolve an extensive range of issues
Demonstrates good judgment in applying appropriate action resolve issues of diverse scope requiring analysis and evaluation of factors
Contributes to establishment of organization's objectives; error in judgment or failure to achieve objectives will have crucial impact and will require extensive addition of resources to correct errors and achieve goals
Receives little instruction and creates own methods for resolution of everyday tasks; receives general directions for new projects; work is assessed for achievement of goals
Affymetrix is an EEO/AA Employer of Minorities/Females/Veterans/Disability/Sexual Orientation and Gender Identity