School of Medicine:
Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.
Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health . Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.
The Duke Division of Allergy and Immunology and Department of Immunology are currently seeking to fill Research Scientist position.
This position is focused on proof-of-concept research and development efforts for therapeutic applications of monoclonal antibodies and cellular immunotherapies. These studies are supported in part through a sponsored research partnership with Cellective BioTherapy, Inc., an early-stage biotech company located in RTP that is developing novel mAb- and cell-based platforms for treating cancer, autoimmunity, and immunodeficiency. This is a unique hands-on opportunity to join a research and development team and help move science from the laboratory to the bedside.
Primary responsibilities include:
- Leadership in the design and execution of proof-of-concept experiments
- Evaluate immunotherapies using in vitro cell culture and functional assays
- Evaluate immunotherapies using in vivo mouse models of human disease
- Developing, optimizing, and validating protocols for formulation and delivery of cellular and mAb therapies
- Generation of SOPs, graphs, slides, protocols, and manuscripts for publication
- Communication of results to colleagues, leadership, and the scientific community Additional responsibilities for the Research Scientist position include:
- Generation of reports for internal use and for communication with partners
- Participation in meetings with private and commercial research sponsors
- Contribution to intellectual property development and prosecution
- Potential for leading in-house research and manufacturing scale-up
Other Credential/Experiential Requirements:
- Min Degree Requirements: Ph.D. or equivalent doctorate (e.g. Sc.D., M.D., D.V.M.).
5 + years of postdoctoral experience conducting scientific research. Multiple publications and notable significant contributions to scientific research.
- Immunology background required, and immuno-oncology background preferred
- Ability to work both independently and lead as part of a collaborative research team
- Prior research experience using multi-color flow cytometry, cell culture, ELISA/ELISpots, FPLC, and animal handling
- Experience using pre-clinical mouse models of disease strongly preferred • Ability to handle multiple complex tasks and prioritize translational research projects effectively
- Strong oral and written English communication skills demonstrated by publications and presentations
In addition to the above requirements, success in the Research Scientist position requires:
- Leadership experience in research, with development production experience preferred
- Experience writing and submitting regulatory documents a bonus
Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Essential Physical Job Functions:
Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.