Principal Scientist 1, Purification, Protein Sciences Research

BioMarin Pharmaceutical Inc. - San Rafael, CA (30+ days ago)4.0


BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. Come join our team and make a meaningful impact on patients’ lives.

SUMMARY

Principal Scientist Level 1 leading a protein purification subteam within Protein Sciences Research

RESPONSIBILITIES

The successful candidate would be a recognized contributor in biologics purification, downstream processing, and protein characterization.
He or she would be an external spokesperson for the organization as demonstrated through patents, academic publications, leadership in the organization of scientific forums, or participation in standard setting and regulatory bodies within the industry.
The successful candidate would exercise latitude in defining objectives and approaches related to critical assignments.
The candidate will have demonstrated consistent exceptional contributions to the products, processes, and technologies of the company and will have frequently participated in major project teams or core teams of late-stage development projects.
He or she would contribute to and influences strategic planning at the departmental and team level.
Extensive background in Akta based protein purification, ultrafiltration/diafiltration, and clarification processes is required.
The successful candidate will be expected to lead a small team of scientists and research associates. The team will be expected to meet the research purification needs to supply preclinical studies that will enable go/no go decisions for therapeutic development candidates.
Ideally, the successful candidate will also have a background in structural biology allowing this person to supervise junior level structural biologists and/or consultants as well as structural based CROs.
EXPERIENCE

Required Skills:
Extensive background in Akta based protein purification, ultrafiltration/diafiltration, and clarification processes is required.

Desired Skills:
Ideally, the successful candidate will also have a background in structural biology allowing this person to supervise junior level structural biologists and/or consultants as well as structural based CROs.

EDUCATION

PhD in relevant field with 10+ years industry experience preferred; MS with 15+ years; BS with 18+ years also acceptable

SUPERVISOR RESPONSIBILITY

The successful candidate may have as many as 3 direct reports as well as 2 or 3 one-under reports