Process Development Associate I

Broad Institute - Cambridge, MA (30+ days ago)4.1


The Broad Institute's Klarman Cell Observatory (KCO), directed by Aviv Regev, is an effort to systematically define cellular circuits in mammalian cells, building on breakthrough technologies and collaborations across scientific disciplines. The Observatory develops and deploys experimental and computational approaches for systematically defining cellular circuits in health and disease. These include capabilities for measuring all cellular components and their connections, reconstructing circuit models with computational algorithms, and producing and delivering perturbing agents to cells.

We are seeking a highly motivated individual to join our team of talented researchers in a highly collaborative research environment. This position offers an opportunity to work with state-of-the art genomic technologies (e.g. single-cell genomics, spatial transcriptomics) on a diverse set of project in the areas of immunology, neuroscience, and cancer research. In support of multiple projects, the successful candidate will be committed to systematically implement innovative research technologies in order to define cellular circuits. Specifically, they will: (i) process a variety of biological samples using several genomic methods; (ii) work to ensure sample preparation goals, timelines, documentation, and requirements are met; (iii) build systematic pipelines for technology implementation/deployment and process steps; (iv) improve existing protocols to generate robust standard operating procedures (SOPs); (v) investigate alternative solutions and troubleshoot processes as needed; and (vi) work to improve current workflow processes in creative and effective ways

KEY RESPONSIBILITIES

Systematically process biological samples for multiple projects using cutting edge genomic technologies

Analyze experimental data and identify methodological problems/challenges. Adjust experimental protocols to ensure best outcomes and project completion in a timely manner

Work with supervisor to plan project requirements and timelines

Document, compile, and assist with interpreting experimental data. Report data to supervisor and team

Operate and maintains automated laboratory equipment to complete investigations

Attend team meetings to share results, plan projects and experiments, ensure that projects support current team goals in a dynamic environment

Consult with other senior scientists or scientific literature as needed

Help to train new lab members, students, interns, and collaborators

Prepare, order, and maintain stocks of necessary reagents, solutions and supplies

REQUIREMENTS

BS degree in Biology or related field required

Must possess at least 1 - 2 years of experience in a research laboratory, preferably in an independent project

Must possess a familiarity with basic molecular biology techniques and sterile techniques

Familiarity with design of experiments and the scientific method required

Experience in a research laboratory and with standard lab equipment required; experience with automation preferred

Strong analytical skills, problem solving ability, and innovation aptitude required

Excellent computer skills required, experience with databases preferred. Must be willing to discover and learn new software and technology applications quickly

Must have strong attention to detail and an ability to multi-task

Excellent written and oral communication skills, interpersonal skills and ability to effectively work as part of a team required

Excellent organization and time management skills

Ability to work independently with minimal supervision

Must thrive in fast-paced and dynamic environment The Broad Institute is redefining the boundaries of science and medicine with an interdisciplinary model designed to meet today's most critical biomedical challenges. Here you will find a supportive and collaborative intellectual environment and a firm commitment to continuously invest in cutting edge technology. At the Broad we are developing the new tools that will enable scientists to begin unlocking the mysteries of genomics.

BENEFITS

Colleagues who are intellectually curious, hard-working, and collaborative with backgrounds spanning science, journalism, policy and finance

Opportunities for professional development and career advancement

Frequent talks and events on science, art, law and policy

A generous benefits package

On-site yoga and boot camp classes

All the coffee and tea you can drink

The Broad Institute will not offer visa sponsorship for this opportunity.

EOE / Minorities / Females / Protected Veterans / Disabilities