Associate Director, High Throughput Screening

Incyte Corporation - Wilmington, DE (30+ days ago)3.8


Incyte Corporation is a fast growing biopharmaceutical company focused on the discovery, development and commercialization of proprietary therapeutics, primarily for oncology. We are part of the S&P 500 and named one of the Forbes most innovative companies in the U.S. Our first commercial product, Jakafi®, is approved in the U.S. for patients with intermediate or high-risk myelofibrosis and for patients with polycythemia vera and projected to reach $1 billion in annual sales this year. We have a diverse and growing portfolio of product candidates, including both small and large molecules. Located in Wilmington, DE, Incyte employees enjoy a rewarding fast paced work environment, competitive compensation, an affordable cost of living and close proximity to Philadelphia, Baltimore, D.C. and the New Jersey and Delaware beaches.

Incyte is seeking a candidate with industry experience to join the Biochemistry, Structural Biology and High Throughput Screening Group. He/she will provide expertise and leadership in biochemistry and lead generation efforts in support of the company’s drug discovery programs. Experience in assay development, lead generation and biochemical support of medicinal chemistry programs is required. As a key member of early drug discovery programs at Incyte, he/she will interact broadly with drug discovery scientists including compound management scientists, structural biologists, biologists and medicinal chemists. The successful candidate will provide leadership and direction as Incyte expands its HTS capabilities. The evaluation, development and integration of new technology will also be an important aspect of this role. Expertise in mechanistic biochemistry, enzymology, biophysics or related field, experience in support of medicinal chemistry programs is required as is experience managing other scientists.

Job Responsibilities

Provide expertise and leadership in the company’s lead finding projects and biochemical support of medicinal chemistry programs
Management of a group of scientists focused on drug discovery

Evaluate, institute and integrate new technology into the drug discovery process

Act as a key member for drug discovery project teams and interact directly with hits to leads and medicinal chemistry groups and biology team members

Participate as member of the new target discovery team and provide expertise in target evaluation and lead discovery strategy

Experience in chemical library acquisition and/or compound handling a plus

Minimum Requirements

Ph.D. in biochemistry or related field, plus a minimum of 6 years of experience
Proven experience with lead generation success in support of drug discovery programs

Good communication and interpersonal skills

Proven experience managing direct and indirect reports

Self-driven, creative and entrepreneurial with ability to support multiple programs simultaneously