Top 14 Software Systemsengineer Jobs

Senior Manufacturing Systems Engineer: Automation - DeltaV (Swing Shift Monday - Friday)
Amgen —Holly Springs, NC
- $136,906.95 - $185,227.05 a year
- Evening shift
- Doctoral degree
- Computer Science
- Master's degree
- Disability insurance
- Health insurance
Senior Manufacturing Systems Engineer: Automation - DeltaV (Wednesday - Saturday Shift)
Amgen —Holly Springs, NC
- $136,906.95 - $185,227.05 a year
- On call
- Doctoral degree
- Computer Science
- Master's degree
- Disability insurance
- Health insurance
Manufacturing Systems Engineer: Automation - PLC
Amgen —Holly Springs, NC
- $105,362.60 - $142,549.40 a year
- On call
- Computer Science
- Master's degree
- High school diploma or GED
Manufacturing Systems Engineer: Automation - DeltaV (Swing Shift Monday - Friday)
Amgen —Holly Springs, NC
- $105,362.60 - $142,549.40 a year
- Evening shift
- Computer Science
- Mid-level
- Master's degree
- Disability insurance
- Health insurance
Manufacturing Systems Engineer: Automation - DeltaV (Sunday - Wednesday Shift)
Amgen —Holly Springs, NC
- $105,362.60 - $142,549.40 a year
- Computer Science
- Mid-level
- Master's degree
- Disability insurance
- Health insurance
Expert Systems Engineer/Solutions Architect
Assured Consulting Solutions —Bethesda, MD
- $220,000 - $250,000 a year
- Full-time
- Azure
- Bachelor of Science
- Office
Quick Apply
Systems Engineer - Mid-Level
Assured Consulting Solutions —St. Louis, MO
- $120,000 - $160,000 a year
- Full-time
- 6 years
- Computer Science
- Mid-level
Quick Apply
Systems Engineer - Expert
Assured Consulting Solutions —Chantilly, VA
- $170,000 - $195,000 a year
- Full-time
- Doctoral degree
- Computer Science
- Engineering
Quick Apply
Systems Engineer - Senior
Assured Consulting Solutions —Springfield, VA
- $150,000 - $175,000 a year
- Full-time
- Computer Science
- 11+ years
- Office
Quick Apply
IT Systems Engineer - Hybrid - Danville, IL
CCMSI —Danville, IL
- $60,000 - $90,000 a year
- Full-time
- Hybrid work
- Azure
- 5 years
- System design
- Paid holidays
- Disability insurance
Quick Apply
Expert Systems Engineer
Assured Consulting Solutions —Chantilly, VA
- $185,000 - $215,000 a year
- Full-time
- Computer Science
- Office
- 3 years
Quick Apply
Space Systems Engineer - Expert
Assured Consulting Solutions —Springfield, VA
- $185,000 - $210,000 a year
- Full-time
- 18 years or older
- Engineering
- Office
Quick Apply
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Senior Manufacturing Systems Engineer: Automation - DeltaV (Swing Shift Monday - Friday)

Amgen -
Holly Springs, NC

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Job Details

$136,906.95 - $185,227.05 a year

Benefits

Disability insurance
Health insurance
Dental insurance
Flexible spending account
Vision insurance
Retirement plan

Qualifications

Team development
Professional development support
Mentoring

Full Job Description

US - North Carolina - Holly Springs

JOB ID: R-244633 LOCATION: US - North Carolina - Holly Springs WORK LOCATION TYPE: On Site DATE POSTED: May. 19, 2026 CATEGORY: Engineering SALARY RANGE: 136,906.95USD -185,227.05 USD

ANC1 F&E Engineering

HOW MIGHT YOU DEFY IMAGINATION?

If you feel likeyou’repart of something bigger,it’sbecause you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over10 million patientsworldwide.It’stime for a career you can be proud of.

Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the AmgenFleXbatch facility will combine the latest in disposable technologies with traditional stainless steel equipment to allow for maximum flexibility in operations TheFleXBatch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.

Senior Manufacturing Systems Engineer:Automation - DeltaV

Live

What you will do

Let’sdo this.Let’schange the world. AsaSeniorManufacturing SystemsEngineer,you will provide automation technical leadership to a group ofautomationengineerswhoare responsible forbuilding andmaintainingvarious automation systems and platforms that support the GMP Drug Substance Plant Operations.

*The schedule for this position willbe:SwingShift3pm - 11pm: MondaythroughFriday.*

In this vital role as a member of the Facilities & Engineering (F&E) Automationteam you will work hand in hand with the capital project team to deliver robustprocessautomation systems tooperatethe new plant. This includes complex and challenging system automation initiatives that require solid understanding of various automation platforms, integration between different platforms, analytical problem-solving techniques, project management, lifecyclemanagementand Operational Excellence.

Responsibilities:

Develop andmaintainthe process control system onEmersonDeltaVdistributed controlsystem(DCS).

Work with process subject matter experts (SMEs) to understand key process requirements and transform them into digital automated solutions.

Collaborate with business partners to understandhowautomationcan improve workflow and productivity. Synthesize requirements from clients,customersor end-users to develop the best automation solutions.

Provide clear documentation for delivered solutions and processes; work closely with QA partners while supporting computerized systems validation processes in aGxPenvironment. Maintain Data Integrity Assessments with the current Amgen and Industry standards.

Build the business processes to support theprojectscope in alignment with project timelines. Develop detailedspecificationand engineering policies and procedures that affect multiple organizational units.

Support commissioning and qualification efforts including Automation Installation Verification/Automation Check Out (IV/ACO) in a fast-paced environment.

On-going operations:

Own and drive tocompletionChange Controls, CAPAs, and Deviations.

Lead and support functional area projects focused on improving processequipment/utilities/facilitiesas well as large/sophisticated capital projects to integrate new drug substance manufacturing technologies into the facility.

Leadandsupport technical root cause analysis, incident investigations, andtroubleshooting onprocess control issues related to plant operations.

Lead and support new product introductions (NPI) ornew technologyintroductions by performingautomationengineering assessments, implementingautomationsystem configurationchanges,and supporting engineering and process qualification runs as applicable.

Manage Day-to-day Operational Support including: 24 x 7 Onsite/On Call Operational Support, Troubleshooting Support to Plant and Mfg. Operations,Process andUtilityAutomatonsystems,Preventive andCorrectiveMaintenance,SystemAdministration,andAutomation Systemspare parts management.

Prepare/review Standard Operating Procedures (SOP) and cGMP documents.

Be constantly curious and feed your passion and interests in groundbreaking technology. Use your given time to look for new and innovative ways to do business differently, better, and more cost effectively.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The automation professional weseekis an engineer with these qualifications.

Basic Qualifications:

High School Diploma / GED and10years of Engineering experience OR

Associate’s Degreeand8years of Engineering experience OR

Bachelor’s Degree and4years of Engineering experience OR

Master’sDegree and2years of Engineering experience OR

DoctorateDegree

Preferred Qualifications:

Degree in Electrical Engineering, Computer Science, Chemical Engineering, Biotech Engineering, or relatedfield.

Direct knowledge of Automation System design, experience inprocess control engineering and troubleshooting with GMP biopharmaceutical production facility equipment/systems automationsuch asmedia, harvest, bioreactors, solution prep, single use mixing vessels, chromatography, TFFL/TFFX, viral filtration, viral inactivation, UF/DF, depth filtration, drug substance fill, CIP/SIP, clean utilities, and integrating various OEM automation software.

Extensive understanding and background in programming, design, installation and lifecycle management of manufacturing process controls,automationand field instrumentation technologies.

Experience with EmersonDeltaVDCS system, Process Control Network design including network segregation,virtualinfrastructure design and implementation,and ability to perform advanced troubleshooting activities,systemintegration using OPC, Foundation Fieldbus, Profibus, andDeviceNettechnologies.Experience withDeltaVLive is preferred.

Ability to interpret and apply GAMPs and GMPs and familiarity with documentation in a highly regulated environmentwith requirements such as 21 CFR Part 11, ASTM 2500, S88, and S95.

Experience in Capital Project Lifecycle Management: Conceptual Design, Scope and cost estimate development, business case development, detailed design, engineering and validation documentation and project execution.

Demonstrated hands-on experience in developing process control strategies for New Product Introduction and New Technology Deployment for Drug Substance Plant Operations.

Demonstrated experience with continuous improvements resulting in enhanced safety, system reliability, and productivity (e.g. cycle times, and reduced plant utilities usage etc.) related to Drug Substance Plant Operations.

The ideal individual must be a self-directed team player ready to mentor and develop engineering staff and embrace a team-based culture that relies on collaboration for effective decision-making.

Strong leadership, technical writing, and communication/presentation skills.

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

Amgen offers a Total Rewards Plancomprisinghealth and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans and bi-annual company-wide shutdowns

Flexible work models, including remote work arrangements, where possible

for a career that defies imagination

In our quest to serve patientsabove all else, Amgen is the first to imagine, and the last to doubt. Join us.

careers.amgen.com

#AmgenNorthCarolina

Apply Now

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Software Systemsengineer jobs

Senior Manufacturing Systems Engineer: Automation - DeltaV (Swing Shift Monday - Friday)

Senior Manufacturing Systems Engineer: Automation - DeltaV (Wednesday - Saturday Shift)

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Manufacturing Systems Engineer: Automation - DeltaV (Sunday - Wednesday Shift)

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