Required Application Materials
A single PDF or Word document containing a resume, letter of interest, and a list of the names and contact information for three (3) professional references is required to apply.
Important Instructions:
When prompted to upload your “resume”, upload your combined documents as one file.
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Please do not upload documents to “Cover Letter” or “References”.
If the required application materials were not uploaded at the “resume” prompt, please withdraw your application, and re-apply to upload your combined documents as one file.
Job Summary
Plans and conducts experiments in microbial immunology and molecular biology under the supervision of Dr. Buka Samten. The studies will include isolation and assessment of phenotype and immune responses of human peripheral blood lymphocytes against Mycobacterium tuberculosis (Mtb) infection by measuring the mRNA levels of the cytokines and transcription factors using quantitative reverse transcription polymerase chain reaction, evaluating the cytokine levels by ELISA and flow cytometry, and the expression and activation levels of transcription factors by Western blotting and electrophoretic mobility shift assays. Work with human peripheral blood monocytes infected with Mtb and evaluation of its growth and the mice infected with Mtb will also be performed.
Major Responsibilities/Duties/Critical Tasks
Plans and conducts experiments in microbial immunology and molecular biology
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Organizes data and performs data analysis
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Writes manuscripts
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Makes scientific presentations
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Designs and conducts experiments by isolation of human peripheral blood mononuclear cells from the blood and assessing the cytokine production and transcription factor expression in the peripheral blood lymphocytes by reverse transcription polymerase chain reaction (RT-PCR), ELISA, SDS-PAGE analysis and Western blotting, electrophoretic mobility shift assays (EMSA); Flow cytometry, mycobacterial growth in human peripheral blood monocytes. Studies of the cytokine production and transcription factor expression in mouse organs infected with Mtb.
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Helps and works collaboratively with other lab personnel
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Maintains accurate records of experiments performed
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Assures that laboratory equipment is properly maintained
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Consults with Dr. Samten regarding laboratory projects
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Performs other work-related duties as assigned
Required Education/Experience
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MS/BA in one of the life sciences with major course work in field of study.
Accompanying Knowledge, Skills, Abilities and Competencies
Work experience related to cellular and molecular biology techniques is essential.
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Runs assays such as Western Blots, qPCR, ELISA, flow cytometry, and carries out data analysis.
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Familiarity with mouse models of tuberculosis or any other respiratory infections is preferred, such as handling and processing of infected mouse tissues, measurement of proteins, and histological analysis of mouse organs.
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Familiarity with primary cell culture techniques and basic statistical methods are also required.
About The University of Texas at Tyler and UT Tyler Health Science Center
The University of Texas at Tyler is part of the prestigious University of Texas System that includes 14 institutions located throughout the state. Founded in 1971, UT Tyler today enrolls 10,000 students and consists of six colleges.
Designated an R2 research institution by the Carnegie Classification of Institutions of Higher Education, UT Tyler supports our surrounding region through innovation intended to uplift communities, spearhead sustainability initiatives, preserve ecosystems and support entrepreneurship. UT Tyler has the highest Carnegie classification in East Texas.
Providing exceptional patient care, comprehensive education and innovative research, The University of Texas at Tyler Health Science Center and UT Health East Texas combine to serve as the university medical center for Northeast Texas and beyond.
For more information, please visit https://www.uttyler.edu/about.
Why work for UT Tyler? Find out more: Why Work for UT Tyler?
Additional Information
The retirement plan for this position is Teacher Retirement System of Texas (TRS), subject to the position being at least 20 hours per week and at least 135 days in length.
This position is security-sensitive and subject to Texas Education Code Section 51.215, which authorizes the employer to obtain criminal history record information. Applicants selected must be able to show proof of eligibility to work in the United States by time of hire.
For more information regarding benefits offered by UT Tyler, please visit https://www.uttyler.edu/offices/human-resources/employees/benefits.
Clinical Position Requirements
Clinical positions may be required to complete a pre-employment health screening, following a contingent job offer, to determine whether they possess the physical capabilities needed to safely fulfill the specific demands of the position. Additionally, clinical positions require compliance with the University’s Vaccine Preventable Disease Policy.
EEO Statement
The University of Texas at Tyler is an Equal Employment Opportunity Employer.
