The Laboratory of Sickle Cell Genetics and Pathophysiology, led by Dr. Swee Lay Thein, in the Sickle Cell Branch of the National Heart, Lung, and Blood Institute, NIH, is seeking a Postdoctoral Fellow to examine the genetic and biological factors underlying the phenotypic variability of sickle cell disease to accelerate translation of basic discovery to therapeutics.
Our laboratory is interested in the study of genetic modifiers and pathophysiology of sickle cell disease. Specifically, potential candidates will utilize a combination of cellular biology, molecular biology, immunology, bioinformatics, and animal studies to identify the mechanisms, as well as biomarkers, that will allow for the monitoring of sickling, acute pain, and inflammation in sickle cell disease. This researcher may explore the use of an investigational drug to modify sickle cell severity in our sickle mice model. More information about our laboratory is available here
What you'll need to apply
Please email a cover letter describing your research interests and career goals, an updated CV, including publications, and the contact information of three references to the email below. Applications will be reviewed on a rolling basis until the position is filled, with a target start date of Spring or early Summer 2026.
Contact name
Tiffany Chen
Interested Candidates must have obtained a Ph.D. or M.D. degree within the last 5 years and possess a background in translational research, molecular biology, or a related field. Ideal candidates will have a strong background in genetics/genomics, immunology, cellular biology, or molecular biology, as demonstrated by first-author publications in peer reviewed journals. They must also will have strong communication, organizational, and time management skills, be detail-oriented, and have the ability to work both independently and as a collaborative team member. He or she must also be willing to work with human samples.