The Yang Laboratory investigates bacterial infections and host immune responses. This position will focus on understanding how Lyme disease pathogens uses newly identified cyclic dinucleotide second messengers to survive in tick vectors and mammalian hosts. The research will also explore host-directed therapeutic strategies to prevent or treat Lyme disease.
Duties and Responsibilities:
70% Independently design and perform a wide variety of laboratory and research tests using standard and special procedures, equipment, and examinations. Techniques include, but not limited to, DNA/RNA/Protein work (cloning, PCR, protein purification), mouse infections, ELISAs, and microscopy. Writing grants and research papers.
20% Lab management and coordination: Supervise research technician(s), postdoctoral fellows, graduate/undergraduate student workers, and hourly employees in standard procedures, methods, and techniques and serve as a resource to laboratory personnel. Coordinate assignments of laboratory personnel and monitor completion. Train all lab personnel as needed and ensure laboratory compliance with safety guidelines through the creation, implementation, and enforcement of standard operating procedures. Coordinate with international partner labs. Assistance with regulatory documents (e.g. IBC, IACUC, IRB) and MTAs. Use discretion to responsibly work within defined budgets. Contribute to budget planning. Conduct recruitment and onboarding of staff.
10% Oversee the proper maintenance and organization of freezer/liquid nitrogen inventories. Manage reagent inventory and ordering of supplies as necessary. Oversee management of animal care, inventory, procedures, and processes. Oversee the set-up and maintenance of lab equipment. Oversee the disposal of hazardous waste. Monitor compliance and manage operations to maintain compliance at all levels.
IU School of Medicine is committed to being a welcoming campus community and we seek candidates whose research, teaching, and community engagement efforts contribute to robust learning and working environments for all students, staff, and faculty. We invite individuals who will join us in our mission to improve health equity and well-being for all throughout the state of Indiana.
Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the nation’s largest concentrations of health sciences companies. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life – the city possesses a variety of professional sports, arts venues, and outdoor recreation areas. Residents of this dynamic city and surrounding suburbs enjoy leading educational systems and top-ranked universities paired with a diverse population. Indianapolis International Airport is a top-ranked international airport that has been named “Best Airport in North America” by Airports Council International for many years. For additional information on life in
Indy: https://faculty.medicine.iu.edu/relocation
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