Job Title: Principal Scientist (Director level), Metabolism Bioscience Research
Location: Gaithersburg, MD (US)
Are you an expert in the skeletal muscle biology? Would you like to apply your research expertise to accelerating innovative science and turn ideas into life changing medicines? Join us to discover future treatments of Cardiovascular, Renal and Metabolic (CVRM) diseases!
We are seeking a passionate and accomplished Principal Scientist with expertise in skeletal muscle physiology, metabolism and drug discovery to join our vibrant research community in the Metabolism Bioscience Division within Early CVRM Research and Development.
The Metabolism Bioscience Division is one of the three main therapeutic research areas within the Bioscience department that delivers candidate drugs into clinical development. The Early CVRM Bioscience department has a dynamic environment that fosters collaboration and innovation. We are a team of professionals who are passionate about advancing science to discover and develop novel therapeutics that will benefit patients with obesity, diabetes and their co-morbidities.
Accountabilities This scientific leadership role offers an exciting opportunity to set strategic direction and shape the future of developing novel therapies for treating obesity, with a focus on mechanisms that will elicit healthy body weight loss and maintenance. You will:
Essential Skills/Experience
PhD in a relevant scientific discipline (e.g., metabolic diseases, musculoskeletal diseases, neuroscience, immunology etc.).
Track record as a project leader or bioscience lead, conducting, planning, and guiding complex scientific projects within multidisciplinary teams.
Desirable Skills/Experience
AstraZeneca is committed to making a difference by fusing data and technology with scientific innovations to achieve breakthroughs. We empower our teams to explore the biology of complex diseases, making bold decisions without fear of failure. Our inclusive environment fosters collaboration across academia, biotechs, and industry, leveraging diverse global knowledge for swift impact on disease. With opportunities for continuous learning and career development, AstraZeneca is where curious minds thrive as we push the boundaries of science to deliver life-changing medicines.
Ready to make an impact? to join our team!
The annual base pay (or hourly rate of compensation) for this position ranges from $172,672.00 - $259,008.00 USD Annual. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
09-Jun-2026
Closing Date
30-Jun-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
