Protheragen is seeking a talented and motivated scientist to direct the Metabolomics Platform.
The successful candidate will work closely and collaboratively with scientists on a range of academic and industrial projects employing targeted and untargeted metabolomics and lipidomics, as well as introducing cutting edge analytical and mass-spec techniques to solve customers’ problems.
Responsibilities:
· Perform LC-MS workflow for metabolomics/lipidomics including sample preparation, method development and execution, method validation, data acquisition and analysis, and report writing;
· Operate and maintain of mass spectrum system including but not limited to ABI/SCIEX QTRAP 6500， Thermo Q Exactive Plus, QQQ
· Demonstrate competency in troubleshooting, optimization and implementation of challenging and innovative LC-MS/MS assays;
· Adhere to established Standard Operating Procedures and contribute to validation protocols, reports and bioanalytical reports.
· Understanding of metabolomics literature and apply theoretical framework to solving problems
Requirements:
· PhD, MSc or BSc in Biochemistry, Biology, Chemistry or similar Life Science
· Significant experience in targeted metabolomics LC-MS method development, method validation and troubleshooting;
· Familiarity with metabolomics platforms including but not limited to AB QTRAP 6500, THERMO QE Plus and QQQ
· Familiarity with metabolite identification and profiling studies;
· Hands-on experience in LC/MS small molecule applications, including method development, quantification, characterization, and structure elucidation.
· Hands-on experience in various biological sample preparation technique such as PP, LLE, and SPE. And
· Hands-on experience and troubleshooting skills on LC separation techniques (i.e. RP, HILIC) and Mass Spec
· Proficiency with mass spectrometry software as well as spreadsheet, word processing, and graphical computer programs;
· Knowledge of LC-MS assay validation guidelines and GLP regulations;
Job Types: Full-time, Contract
Pay: $100,000.00 - $150,000.00 per year
Benefits:
- 401(k) matching
- Health insurance
- Retirement plan
Work Location: In person
