A postdoctoral research opportunity is immediately available in the Pisu lab at the Tulane National
Biomedical Research Center to investigate macrophage heterogeneity and host–pathogen interactions
during Mycobacterium tuberculosis infection. We are seeking a highly motivated postdoctoral fellow
interested in pursuing an academic career in immunology, host–pathogen biology, and translational
infectious-disease research.
The laboratory uses murine and non-human primate (NHP) models to define how alveolar and
monocyte-derived macrophage subsets influence bacterial control and immune regulation in the lung.
Ongoing projects include NIH- and startup-funded studies examining macrophage functional diversity,
mechanisms of epigenetic and transcriptional reprogramming, and how vaccination or innate immune
training modulate susceptibility to infection.
The fellow will perform molecular, cellular, and microbiological work, including cloning, CRISPR/Cas9
editing, RNA-seq and multiomic library preparation, flow cytometry, microscopy, macrophage infection
assays, and murine infection studies, and will analyze resulting datasets using R or Python pipelines. The
position offers opportunities for publication, collaboration with multidisciplinary teams, and
development of independent research directions supported by extensive core services and BSL-3
facilities at TNBRC.
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