Battelle delivers when others can’t. We conduct research and development, manage national laboratories, design and manufacture products and deliver critical services for our clients—whether they are a multi-national corporation, a small start-up or a government agency.
We recognize and appreciate the value and contributions of individuals from a wide range of backgrounds and experiences and welcome all qualified individuals to apply.
We are seeking a curious and passionate scientist to lead intracellular delivery and formulation development for a biostabilization platform. In this role, you will design and execute high-throughput screening campaigns, integrate delivery and formulation strategies, and collaborate across a multi-institution team of academic and commercial partners.
This position offers direct ownership of a core technical thrust within a high-impact, federally funded program, providing a unique opportunity to drive meaningful scientific advancement at the intersection of cell biology, bioengineering, and translational research.
As a Cell Delivery and Formulation Scientist, the selected individual will lead and contribute to intracellular delivery and formulation development across a multidisciplinary, federally funded program. Responsibilities may include:
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Develop and optimize intracellular delivery of cargo into multiple mammalian cell types, including parameter development on reference delivery systems
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Design, formulate, and optimize cocktails for cell stabilization and recovery
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Plan and execute high-throughput screening of delivery and formulation conditions using automated liquid handling, plate-based viability and metabolic assays, and flow cytometry
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Define quantitative acceptance criteria; analyze viability, apoptosis, metabolic activity, and recovery data; and drive down-selection of lead conditions
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Coordinate technical execution with academic and commercial partners, including transfer of protocols and materials
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Author technical reports, standard operating procedures, and program deliverables; present results to internal leadership and sponsors
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Integrate delivery and formulation with downstream bioprocessing and support recovery optimization
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Maintain accurate laboratory records and adhere to safety and quality standards
- Ph.D. in Bioengineering, Biomedical Engineering, Mechanical Engineering, Chemical Engineering, Cell or Molecular Biology, Biophysics, Materials Science, or a related field with 0–2 years of experience; or an M.S. with 2+ years of relevant experience
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Demonstrated experience in intracellular delivery or cell membrane permeabilization using one or more physical or non-viral methods (e.g., microfluidic cell squeezing/mechanoporation, electroporation or nucleofection, sonoporation, microinjection, nanoneedle/nanostraw, or comparable techniques)
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Hands-on expertise in mammalian cell culture, including primary cells and cell lines, and sterile technique
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Experience developing and running quantitative cell-based assays (viability, cytotoxicity, apoptosis, metabolic activity) and flow cytometry
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Experience formulating and optimizing biological formulations or protectants, or a strong foundation in formulation science
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Strong data analysis skills with the ability to define and apply acceptance criteria
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Strong analytical, organizational, and written and verbal communication skills; ability to work independently and lead within a multidisciplinary team
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Applicants must have authorization to work in the United States. We are unable to sponsor or take over sponsorship of any employment Visa at this time.
- Experience with cell stabilization technologies such as desiccation, cryopreservation, or lyophilization
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Familiarity with protectant biology and anhydrobiosis
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Experience with high-throughput screening, automated liquid handling, and design of experiments (DOE)
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Proficiency with data analysis tools (e.g., GraphPad Prism, R, Python, FlowJo)
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Track record of peer-reviewed publications or conference proceedings
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Experience with cell and gene therapy products or manufacturing (e.g., CAR-T, stem cell, or other cell-based therapeutics)
Battelle is committed to fair and equitable compensation practices. The salary range for this role is $66,500 – $94,000 per year, in addition to our comprehensive benefits package. A candidate's salary is determined by various factors, including but not limited to education, relevant work experience, skills, and certifications. Salary ranges may vary based on geographic location and market conditions.
Benefits: Live an Extraordinary Life
We care about your well-being, not just on the job. Battelle offers comprehensive and competitive benefits to help you live your best life.
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Balance life through a compressed work schedule: Most of our team follows a flexible, compressed work schedule that allows for every other Friday off—giving you a dedicated day to accomplish things in your personal life without using vacation time.
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Enjoy enhanced work flexibility, including a hybrid arrangement: You have options for where and when you work. Our Together with Flexibility model allows you to work 60% in-office and 40% remote, with Monday and Tuesday as common in-office days, dependent on team and position needs.
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Take time to recharge: You get paid time off to support work-life balance and keep motivated.
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Prioritize wellness: Stay healthy with medical, dental, and vision coverage with wellness incentives and benefits plus a variety of optional supplemental benefits.
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Better together: Coverage for partners, gender-affirming care and health support, and family formation support.
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Build your financial future: Build financial stability with an industry-leading 401(k) retirement savings plan. For most employees, we put in 5 percent whether you contribute or not, and match your contributions on top of that.
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Advance your education: Tuition assistance is available to pursue higher education.
A Work Environment Where You Succeed
For brilliant minds in science, technology, engineering and business operations, Battelle is the place to do the greatest good by solving humanity’s most pressing challenges and creating a safer, healthier and more secure world.
You will have the opportunity to thrive in a culture that inspires you to:
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Apply your talent to challenging and meaningful projects
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Receive select funding to pursue ideas in scientific and technological discovery
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Partner with world-class experts in a collaborative environment
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Nurture and develop the next generation of scientific leaders
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Give back to and improve our communities
Vaccinations & Safety Protocols
Battelle may require employees, based on job duties, work location, and/or its clients’ requirements to follow certain safety protocols and to be vaccinated against a variety of viruses, bacteria, and diseases as a condition of employment and continued employment and to provide documentation that they are fully vaccinated. If applicable, Battelle will provide reasonable accommodations based on a qualified disability or medical condition through the Americans with Disabilities Act or the Rehabilitation Act or for a sincerely held religious belief under Title VII of the Civil Rights Act of 1964 (and related state laws).
Battelle is an equal opportunity employer. We provide employment and opportunities for advancement, compensation, training, and growth according to individual merit, without regard to race, color, religion, sex (including pregnancy), national origin, sexual orientation, gender identity or expression, marital status, age, genetic information, disability, veteran-status veteran or military status, or any other characteristic protected under applicable Federal, state, or local law. Our goal is for each staff member to have the opportunity to grow to the limits of their abilities and to achieve personal and organizational objectives. We will support positive programs for equal treatment of all staff and full utilization of all qualified employees at all levels within Battelle.
The above statements are intended to describe the nature and level of work being performed by people assigned to this job. They are not intended to be an exhaustive list of all responsibilities, activities and skills required of staff members. No statement herein is intended to imply any authorities to commit Battelle unless special written permission is granted by Battelle's Legal Department.
For more information about our other openings, please visit www.battelle.org/careers
