Location: Hybrid Role – based in Princeton, NJ
Reports to: Head of Commercial
About Cartesian Therapeutics:
Cartesian Therapeutics is a clinical-stage biotechnology company developing mRNA CAR-T therapies for autoimmune diseases. Our mission is to expand the reach of cell therapy to patients living with serious autoimmune conditions through scientific rigor, collaboration, and innovation.
About the Role:
As we look ahead to the upcoming completion of our Ph3 Generalized Myasthenia Gravis trial, along with the continued progression of our trials in Myositis and Juvenile Dermatomyositis, Cartesian is further building-out our Commercial Organization.
Thus, we are seeking a Senior Director, CommercialMedical Operations, which will report to the Head of Commercial and serve as a key member of the Commercial leadership team. This role will help build and operationalize commercialmedical infrastructure in partnership with leadership to enable successful commercialization, ensuring data-driven decision-making, operational excellence, and seamless execution.
Key Responsibilities:
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Forecasting, Data,Analytics: Lead development and continuous refinement of commercial forecasts, with key cross-functional partners to drive accuracy and alignment, and establish scalable dataanalytics capabilities to support business needs
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Market ResearchCompetitive Intelligence: Partner with marketing to define key business questions and research priorities; lead all market research efforts (may include syndicated, qualitative, and quantitative) and competitive intelligence monitoring (and lead cross-functional CI Council) to generate actionable insights that inform strategy, positioning, and execution
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Field EnablementEffectiveness: Coordinate field enablement efforts across sales, market access, account management, and medical, in close partnership with each respective functional leader, ensuring field teams are equipped with right-sized processes, tools, insights, targeting, and training to drive execution, coordination, compliance, and performance
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CommercialMedical Systems: Serve as the business lead for commercialmedical systems roadmap to define business needs and processes in partnership with commercial peers, medical, and IT, (including CRM, data infrastructure, analytics platforms, and field tools)
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MLR OperationsGovernance: Drive MLR processesworkflow, in partnership with heads of commercial, legal, medical,regulatory compliance, to ensure efficient, compliant, and timely reviewapproval of materials
- Market AccessTrade Operations: Partner closely with head of value, access, and trade on all aspects of market access operations, including contracting analytics, access performance reporting, pricing and gross-to-net planning, tradedistribution modelpartner performance to ensure efficient product flow, visibility, and alignment with objectives
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TrainingCapability Development: Support the development and execution of a scalable training strategy across commercial and medical teams (in collaboration with human resources, commercial leadership peers, and medical affairs), to enable pre-launch effectiveness, launch readiness, and ongoing capability-building
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Data-Driven PerformanceKPI Management: Support commercialmedical leadership in establishing and operationalizing right-sized KPIs, dashboards, and performance management frameworks to enable a test-and-learn culture for optimized execution
- Cross-Functional Collaboration: Partner closely with commercial leadership, along with medical affairs, finance, IT, regulatory, and legal/compliance to ensure aligned planning, integrated execution, and effective governance
Qualifications:
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BioPharma Experience: 10+ years of progressive BioPharma experience across a mix of commercial operations functions
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Leadership Profile: Purpose-driven leader that values and role-models innovation, collaboration, integrity, and patient-centric thinking. Proven "player-coach" with the agilityhumility to operate seamlessly between strategy and execution; known for building and leading high-performing teams and driving impact in resource-constrained, fast-paced, high-science environments
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Operations Expertise: Strong expertise in forecasting, data, analytics, sales and marketing operations, market research, competitive intelligence, access operations, and field enablement, (medical operations experience an additional plus); strong understanding of commercialization workflows, processes, and compliance requirements
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SystemsInfrastructure: Experience implementing and optimizing commercialization systems (e.g., CRM, analytics platforms, data infrastructure, field tools) in collaboration with IT to support launch and scale
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StrategicAnalytical Excellence: Strong ability to synthesize complex data into clear insights and recommendations; experience enabling data-driven decision-making and linking analytics to business performance
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CollaborationInfluence: Strong communication, leadership presence, and stakeholder influence skills, with a highly collaborative, cross-functional mindset
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Therapeutic Experience: Experience with successful launch of novel or first-in-class therapy(ies); cell and/or gene therapy, rare disease, neurology, rheumatology, and/or hematology/oncology preferred
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Education: Bachelor's degree require; Advanced degree (MBA, MPH, PhD, PharmD, or equivalent) preferred; relevant work experience will be considered
Travel Expectations: ~15–35% travel
