Top 61 / python developer Jobs in Columbus

Principal Software Engineer
CVS Health —Columbus, OH
- $144,200 - $288,400 a year
- Full-time
- Computer science
- Computer Science
- System design
- Health insurance
- Dental insurance
AWS Big Data Lead Software Engineer
JPMorganChase —Columbus, OH
- Full-time
- 5 years
- System design
- Linux
- Health insurance
- Tuition reimbursement
Manager of Software Engineering
JPMorganChase —Columbus, OH
- Full-time
- Azure
- Writing skills
- Java
- Health insurance
- Tuition reimbursement
7d
System Security Engineer/Software Engineer Lead
Battelle —Columbus, OH
- $110,000 - $140,000 a year
- Full-time
- Hybrid work
- Computer Science
- Office
- Master's degree
- Wellness program
- Health insurance
1d
Sr AI Machine Learning Engineer
The Hartford —Columbus, OH
- $117,200 - $175,800 a year
- Full-time
- Hybrid work
- 5 years
- DevOps
- System design
Software Engineer (Site Reliability)
NetJets —Columbus, OH
- Computer Science
- System design
- Office
- Health savings account
- Disability insurance
Model Based Development Engineer
KPIT Technologies GmbH —Columbus, OH
- Full-time
- System design
- Mentoring
- Senior level
- Health savings account
- Paid holidays
9d
Full Stack Engineer Manager
Accenture —Columbus, OH
- $87,400 - $293,800 a year
- Full-time
- Hybrid work
- Writing skills
- Analysis skills
- Mentoring
- Paid holidays
- Disability insurance
Embedded UI Firmware Engineer - Thermal Platform
Vertiv —Westerville, OH
- Full-time
- Computer Science
- System design
- Mid-level
Solution Engineer Sr
AEP Service Corporation —Gahanna, OH
- $87,633 - $109,543 a year
- Weekends as needed
- Computer Science
- 5 years
- Office
- Tuition reimbursement
7d
DevOps Engineer
Express —Columbus, OH
- Email
- Computer Science
- System design
- Office
Senior Cloud Engineer
Safelite Group —Columbus, OH
- Full-time
- Hybrid work
- System design
- Office
- 8 years
- Paid holidays
- Health insurance
Software Engineer - Senior
Capital Group Companies —London, OH
- Full-time
- Computer science
- Computer Science
- Mentoring
- Health insurance
- Benefits from day one
17h
Lead Software Engineer - Databricks/Spark/AWS
JPMorganChase —Columbus, OH
- Full-time
- 5 years
- SQL
- Mentoring
- Health insurance
- Tuition reimbursement
Python Terraform AWS DevOps MLOps Lead Software Engineer
JPMorganChase —Columbus, OH
- Full-time
- Azure
- 5 years
- Senior level
- Health insurance
- Tuition reimbursement
Senior Software Engineer
Path Robotics —Columbus, OH
- Java
- Mentoring
- APIs
- Paid parental leave
- Dental insurance
Quick Apply
Senior Lead Software Engineer -Java/AWS/Agentic
JPMorganChase —Columbus, OH
- Full-time
- 5 years
- System design
- SQL
- Health insurance
- Tuition reimbursement
Senior Software Engineer - Robotics, Perception (C++, Python)
Path Robotics —Columbus, OH
- Computer Science
- 5 years
- System design
- Paid parental leave
- Health insurance
Quick Apply
Delivery Management Engineer II
Deloitte —Columbus, OH
- $86,400 - $170,900 a year
- Full-time
- Azure
- Computer Science
- Up to 50% travel
Software Simulation Engineer, Sensor Rendering
Path Robotics —Columbus, OH
- Computer Science
- Mentoring
- Senior level
- Paid parental leave
- Dental insurance
Quick Apply

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Principal Software Engineer

CVS Health -
Columbus, OH

Apply Now

Job Details

Full-time
$144,200 - $288,400 a year

Benefits

Health insurance
Dental insurance
Paid time off
Vision insurance

Qualifications

AI models
Computer science
Software engineering
High availability solutions design
Improving system uptime or availability
IT system monitoring
System performance optimization
System design
AI platforms (beyond public GPTs)
Scalable systems
Enterprise software systems development
JavaScript frameworks
Prompt engineering
Microservices
Event-driven architecture
Machine learning cloud services
Machine intelligence
Model deployment
SRE
REST
Systems engineering
Cloud Native Design
Scalability
Production monitoring
System deployment
UI implementation
Front-end component implementation
Distributed computing
Real-time data processing implementation
System tuning

Full Job Description

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time.

Position Summary

We are hiring a Principal Software Engineer — a deeply hands-on technical leader who thrives on solving complex problems, writing production code, and elevating the engineers around them.

You will serve as the senior engineering voice across a portfolio of mission-critical clinical decision-support applications. These systems combine low-latency distributed architectures with advanced LLM, OCR, and ML pipelines running on Google Cloud.

This is not an “architect-from-the-sidelines” role. You will actively design systems, write critical code, ship to production, support live environments, and mentor engineers across UI, backend, and ML. Success in this role is measured by the quality, performance, reliability, and clinical impact of what you deliver—not by presentations.

What You’ll Do

Own architecture and execution
Lead the technical direction of a real-time, multi-service clinical platform on GCP, while personally building the most critical and performance-sensitive components.
Build production-grade LLM systems
Design and operate scalable LLM pipelines (e.g., Claude, Gemini, GPT-4-class) including prompt engineering, structured outputs, evaluation frameworks, retrieval/vector search, OCR-based document understanding, grounding, guardrails, and hallucination mitigation.
Deliver real-time, high-performance systems
Architect distributed, event-driven, streaming services that support sub-second clinician experiences under heavy load, with strict SLOs and strong fault tolerance.
Operationalize machine learning
Lead deployment and lifecycle management of models on Vertex AI, including feature pipelines, model registries, drift detection, A/B and shadow testing, and CI/CD-integrated quality controls.
Design for scalability and change
Build flexible APIs, microservices, and data contracts that support rapid iteration, backed by strong testing, observability, and progressive delivery practices.
Raise the engineering bar
Drive high-quality code reviews, establish standards across testing, CI/CD, security, and observability, and mentor engineers across full-stack and ML disciplines.
Own outcomes end-to-end
Translate ambiguous clinical and business needs into delivered solutions, monitor real-world performance, and continuously iterate based on data.
Partner across disciplines
Collaborate with Data Science, Product, Clinical SMEs, AI Governance, and Security teams to ensure solutions meet enterprise standards for compliance, privacy, and safety.

Required Qualifications:

10+ years of software engineering experience with a strong record of delivering production systems at scale
5+ years as a hands-on Staff or Principal-level engineer (actively coding, not removed from implementation)
Expert proficiency in Python including performance tuning, concurrency, and system optimization
5+ years building real-time distributed systems (event-driven, streaming, Pub-Sub) with clear latency and reliability requirements
5+ years working in a major public cloud (GCP preferred: Vertex AI, GKE, Cloud Run, Pub/Sub, BigQuery, IAM, etc.)
Deep experience with microservices architecture, API design (REST), and resilient systems (retries, backpressure, tracing)
3+ years building and operating production ML systems (MLOps, monitoring, retraining, deployment pipelines)
3+ years developing LLM-powered applications in production, including prompt design, RAG/vector search, evaluation frameworks, and performance optimization
Experience building modern UI components with React or Angular
Strong computer science fundamentals, including distributed systems, algorithms, and concurrency

Preferred Qualifications

Experience operating LLM systems in regulated environments (PII/PHI, governance, security, auditability)
Familiarity with vector databases (e.g., Vertex Vector Search, Pinecone, Weaviate, pgvector) and advanced retrieval techniques
Experience designing evaluation frameworks for LLM systems (gold datasets, regression testing, LLM-as-judge)
Strong background in CI/CD, SRE practices, and SLO-driven engineering
Experience with healthcare data standards (FHIR, HL7) and compliance frameworks (HIPAA, HITRUST)
Strong communication skills, with the ability to explain complex systems to both technical and non-technical audiences
Proven track record of mentoring engineers into senior and staff roles

Education:

Bachelor’s degree in Computer Science or a related field (or equivalent experience)
Master’s or PhD in Computer Science, Machine Learning, or a related discipline is a plus

Pay Range

The typical pay range for this role is:

$144,200.00 - $288,400.00

This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, geography and other relevant factors. This position is eligible for a CVS Health bonus, commission or short-term incentive program in addition to the base pay range listed above. This position also includes an award target in the company’s equity award program.

Our people fuel our future. Our teams reflect the customers, patients, members and communities we serve and we are committed to fostering a workplace where every colleague feels valued and that they belong.

Great benefits for great people

We take pride in offering a comprehensive and competitive mix of pay and benefits that reflects our commitment to our colleagues and their families.

This full‑time position is eligible for a comprehensive benefits package designed to support the physical, emotional, and financial well‑being of colleagues and their families. The benefits for this position include medical, dental, and vision coverage, paid time off, retirement savings options, wellness programs, and other resources, based on eligibility.

Additional details about available benefits are provided during the application process and on Benefits Moments.

We anticipate the application window for this opening will close on: 10/02/2026

Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state and local laws.

Apply Now

Refine Your Search

/ python developer jobs in columbus

Principal Software Engineer

AWS Big Data Lead Software Engineer

Manager of Software Engineering

System Security Engineer/Software Engineer Lead

Sr AI Machine Learning Engineer

Software Engineer (Site Reliability)

Model Based Development Engineer

Full Stack Engineer Manager

Embedded UI Firmware Engineer - Thermal Platform

Solution Engineer Sr

DevOps Engineer

Senior Cloud Engineer

Software Engineer - Senior

Lead Software Engineer - Databricks/Spark/AWS

Python Terraform AWS DevOps MLOps Lead Software Engineer

Senior Software Engineer

Senior Lead Software Engineer -Java/AWS/Agentic

Senior Software Engineer - Robotics, Perception (C++, Python)

Delivery Management Engineer II

Software Simulation Engineer, Sensor Rendering

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