Top 23 Medicinal chemist Jobs in California

Computational Medicinal Chemist
Novartis —San Diego, CA
- $126,000 - $257,400 a year
- Full-time
- 3 years
- Doctor of Philosophy
- Senior level
- Health insurance
- 401(k) matching
2d
Scientist, Organic Chemistry
Kodiak Sciences Inc. —Palo Alto, CA
- Full-time
- Doctor of Philosophy
- Senior level
- Communication skills
Scientist, Peptide Chemistry
CALICO —South San Francisco, CA
- $135,000 - $145,000 a year
- Analysis skills
- Doctor of Philosophy
- Team management
Senior Scientist, Medicinal Chemistry (On-site)
Neomorph, Inc. —San Diego, CA
- $164,000 - $186,000 a year
- Management
- Bachelor of Science
- 11+ years
- Paid parental leave
- Health savings account
Director, Medicinal Chemistry
Protagonist Therapeutics —Newark, CA
- $210,000 - $250,000 a year
- Doctor of Philosophy
- Mentoring
- Pediatrics
Quick Apply
Principal Scientist, Medicinal Chemistry
Neurocrine Bioscience —San Diego, CA
- $130,800 - $179,000 a year
- Full-time
- Psychiatry
- Computer literacy
- Bachelor of Science
- Paid holidays
- Health insurance
Principal Scientist, Medicinal Chemistry
Iambic Therapeutics, Inc —San Diego, CA
- $152,000 - $190,000 a year
- Full-time
- Bachelor of Science
- Office
- 8 years
- Flexible spending account
- 401(k) matching
Sr Associate Scientist I or II, Medicinal Chemistry
Iambic Therapeutics, Inc —San Diego, CA
- $84,000 - $120,000 a year
- Full-time
- Bachelor of Science
- 3 years
- Bachelor's degree
- Flexible spending account
- 401(k) matching
Analytical Chemistry Principal Research Associate
Vertex Pharmaceuticals —San Diego, CA
- $85,700 - $128,500 a year
- Full-time
- 5 years
- Writing skills
- Mid-level
- Loan repayment program
- Dental insurance
Staff Scientist, Chemistry
Cellanome —Foster City, CA
- $140,000 - $200,000 a year
- 5 years
- Doctor of Philosophy
- Quality control
- Health insurance
- 401(k)
Director/Senior Director, Medicinal Chemistry
Iambic Therapeutics, Inc —San Diego, CA
- $196,000 - $280,000 a year
- Full-time
- Bachelor of Science
- 11+ years
- Office
- Flexible spending account
- 401(k) matching
Scientist II/Senior Scientist, Medicinal Chemistry
General Proximity —San Francisco, CA
- Email
- 3 years
- Analysis skills
- Doctor of Philosophy
- Health insurance
- Dental insurance
Quick Apply
Scientist, Life Science Organic Chemistry - San Diego, CA
dsm-firmenich —San Diego, CA
- Online Application
- 5 years
- English
- Analysis skills
- Opportunities for advancement
Medicinal Chemists/Adjunct Professor Series*
UC San Francisco Academic —San Francisco, CA
- $112,500 - $297,200 a year
- Online Application
- University
- Doctor of Philosophy
- Mentoring
Senior Scientist / Principal Scientist – Process Chemistry
Treeline Biosciences —San Diego, CA
- $166,380 - $189,533 a year
- 3 years
- Doctor of Philosophy
- Travel
Quick Apply
Senior Research Associate 1 (Contract)
Eikon Therapeutics —Millbrae, CA
- $48 - $58 an hour
- Contract
- Mid-level
- Master's degree
- Bachelor's degree
- AD&D insurance
- Paid holidays
Quick Apply
1d
Postdoctoral Scientist
Eli Lilly —San Diego, CA
- $58,000 - $123,200 a year
- Full-time
- Doctor of Philosophy
- US work authorization
- Senior level
- Health insurance
- Dental insurance
10d
Senior Scientist, Organic Chemistry - San Diego, CA
dsm-firmenich —San Diego, CA
- Online Application
- 5 years
- English
- Analysis skills
- Health insurance
- Paid time off
Principal Scientist, Peptide Therapeutics
Genentech —San Francisco, CA
- $143,200 - $265,900 a year
- Online Application
- 3 years
- Machine learning
- Doctor of Philosophy
Senior Principal Scientist, Peptide Therapeutics
Genentech —San Francisco, CA
- $168,600 - $313,000 a year
- Online Application
- 7 years
- Analysis skills
- Doctor of Philosophy

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medicinal chemist jobs near california

Computational Medicinal Chemist

Novartis -
San Diego, CA

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Job Details

Full-time
$126,000 - $257,400 a year
2 days ago

Benefits

Health insurance
401(k) matching

Qualifications

Computational research
Data visualization software proficiency
Computational biology
Publishing papers in peer-reviewed journals
Manuscripts for peer-reviewed journals
Project leadership
Pharmaceutical research experience
Data visualization projects

Full Job Description

Summary

Join our vibrant and innovative Computer-Aided Drug Discovery (CADD) team in California, where we bring together diverse talents to redefine the way Biomedical Research discovery teams validate and develop new targets. We are a driving force behind drug discovery, and we are now eagerly searching for an exceptional computational scientist like you to join our ranks.

Imagine the opportunity to unlock hidden knowledge and disruptive insights from the vast and invaluable data collected by one of the world's most renowned pharmaceutical companies. We need your expertise, experience, and unwavering passion to help us extract this wealth of information. Collaborating with a multidisciplinary group of scientists, you will be at the forefront of crafting inventive solutions to the most pressing drug discovery challenges, forging new paths toward groundbreaking medicines.

Are you ready to seize this extraordinary chance to make a significant impact in the field of drug discovery? We invite you to embark on this thrilling journey with us, as we push the boundaries of what's possible in scientific exploration. Join our team and be part of a revolution that will shape the future of medicine.

Together, we will transform the landscape of drug discovery, accelerate breakthroughs, and change lives. Apply now and let your expertise shine in our dynamic and forward-thinking environment.

About the Role

Internal Job Title: Senior Expert I/II, Data Science

Position Location: San Diego, CA, hybrid

Your Responsibilities Include:

Drive the design of medicinal chemistry efforts by applying in-depth knowledge of structure-activity relationships (SAR), structure-based and ligand-based drug design, a profound understanding of target biology, and predictive methods for assessing on- and off-target activity, physical properties, pharmacokinetics/pharmacodynamics (PK/PD), and synthetic feasibility.
Thrive at the intersection of experimental and groundbreaking digital technologies, with a particular emphasis on expertise in machine learning, active learning and physics-based CADD methodologies as applied to small molecule drug discovery as well as in the induced proximity space.
Stay abreast of scientific literature and engage with internal and external scientists to incorporate biological insights into lead characterization and screening initiatives.
Collaborate with interdisciplinary project teams to facilitate effective decision-making throughout the target identification, lead optimization and drug candidate nomination process. This involves applying and developing predictive models based on high-content and time-resolved screening data, including imaging techniques.
Drive hypothesis generation to enhance clinical success rates for programs involving small molecules, peptides, RNAs, protein degradation, molecular glues, transient covalent inhibitors, and kinetic stabilization of drug-target complexes.
Take a leading role in cross-disciplinary mechanistic studies using physics-based modeling and simulation, biophysical characterization, and cellular validation. These studies will inform the strategic targeting strategies of discovery projects, aiming for optimal mechanisms of action (MoAs).

Essential Requirements:

PhD in medicinal chemistry, computational chemistry, computational biology, computational chemical biology, or a related field. Candidates with a laboratory-based background in chemistry and biology, supplemented with strong computational experience, are also encouraged to apply. We will also consider MS applicants with 6+ years of relevant Pharma/biotech experience.
3+ years of experience working with project teams in a drug discovery environment.
Proven track record of innovation through analogue design, leading to significant impact on discovery projects.
Familiarity with computational drug design tools (e.g. Schrdoinger, CCG, OpenEye, etc.), high-performance computing environments, and strong publication history in peer-reviewed journals.

Proactively anticipates project needs with a clinical focus.
Demonstrates rigor and diligence in idea substantiation, analogue design, and experimentation.
Strong team orientation with multitasking and adaptability in support and leadership roles.
Effective listener with excellent written and oral communication skills.
Proficient in data visualization to effectively communicate insights.

Compensation & Benefits:

The salary for this position is expected to range between $126,000 and $234,000 USD annually for Senior Expert I, Data Science, and $138,600 and $257,400 USD annually for Senior Expert II, Data Science. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

To learn more about the culture, rewards and benefits we offer our people click here.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.
Read our handbook (PDF 30 MB)

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility & Reasonable Accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Division

Biomedical Research

Business Unit

Research

Location

USA

State

California

Site

San Diego

Company / Legal Entity

U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.

Functional Area

Data and Digital

Job Type

Full time

Employment Type

Regular

Shift Work

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Refine Your Search

medicinal chemist jobs in california

Computational Medicinal Chemist

Scientist, Organic Chemistry

Scientist, Peptide Chemistry

Senior Scientist, Medicinal Chemistry (On-site)

Director, Medicinal Chemistry

Principal Scientist, Medicinal Chemistry

Principal Scientist, Medicinal Chemistry

Sr Associate Scientist I or II, Medicinal Chemistry

Analytical Chemistry Principal Research Associate

Staff Scientist, Chemistry

Director/Senior Director, Medicinal Chemistry

Scientist II/Senior Scientist, Medicinal Chemistry

Scientist, Life Science Organic Chemistry - San Diego, CA

Medicinal Chemists/Adjunct Professor Series*

Senior Scientist / Principal Scientist – Process Chemistry

Senior Research Associate 1 (Contract)

Postdoctoral Scientist

Senior Scientist, Organic Chemistry - San Diego, CA

Principal Scientist, Peptide Therapeutics

Senior Principal Scientist, Peptide Therapeutics

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