The Role
The GxP Endpoint Engineer will serve as the primary owner of the SCCM environment supporting Moderna’s GxP operations, ensuring all configurations, deployments, and processes align with Quality Assurance (QA) guidance and compliance requirements.
This role is responsible for building and maintaining a validated, audit-ready SCCM infrastructure that supports operating system deployments, in-place upgrades, patching, and application distribution. The engineer will define and document GxP configuration standards, implement quality-controlled deployment practices, and ensure every change follows approved validation and change control processes.
In collaboration with Endpoint Engineering, GxP Support, QA, Cloud, Identity, and Lab Engineering teams, this individual will drive consistent, compliant endpoint management practices. The position also includes building knowledge base (KB) documentation for support teams, engaging with application owners to ensure deployment success, and managing escalations tied to GxP device operations.
Here’s What You’ll Do
Own and manage the SCCM GxP environment, ensuring all configurations, task sequences, and deployments comply with QA guidance and validation standards.
Design, document, and maintain standard operating procedures (SOPs) and configuration baselines specific to GxP systems.
Implement and monitor strict QC processes for all deployments, including peer review, QA validation, and change control sign-off prior to production release.
Oversee all operating system deployments and in-place upgrades (IPU) for validated systems, ensuring consistent execution under GxP change control.
Manage patching cycles, including Microsoft and third-party updates, coordinating with QA, GxP Support, and Application Owners to plan, validate, and document each phase.
Create and maintain deployment and compliance reports, providing transparency to QA and management on patch and configuration status across the GxP fleet.
Collaborate with Application Owners and GxP Support teams to coordinate deployments, validate installations, and resolve environment-specific issues.
Develop and publish Knowledge Base (KB) articles and operational guides for support teams and end users related to SCCM processes, patching, and imaging.
Serve as the escalation point for packaging, deployment, and compliance failures impacting GxP systems.
Partner with QA to participate in audits, provide system validation evidence, and ensure documentation accuracy across all controlled activities.
Contribute to the ongoing evolution of how SCCM operates in Moderna’s validated environment, helping to design scalable, compliant frameworks for automation and reporting.
Here’s What You’ll Need (Basic Qualifications)
6+ + years of experience in SCCM/MECM administration, including task sequences, OSD, collections, compliance baselines, and application deployments.
Proven experience managing systems in regulated (GxP, GMP, or validated) environments, adhering to QA and change control processes.
Strong understanding of QA, QC, and validation principles within endpoint management.
Experience performing in-place upgrades (IPUs), PXE imaging, and patch management in controlled environments.
Hands-on experience with third-party patching tools and their integration with SCCM.
Familiarity with ServiceNow for change control, approval workflows, and incident tracking.
Ability to produce comprehensive documentation, SOPs, and KBs aligned with GxP validation standards.
Strong collaboration skills to engage with QA, Application Owners, and Support teams on validation, testing, and incident management.
Here’s What You’ll Bring to the Table (Preferred Qualifications)
Analytical mindset and attention to detail to ensure every configuration and deployment meets compliance and performance expectations.
Bachelor’s degree in Information Technology, Computer Science, or a related technical discipline.
Experience with co-managed SCCM + Intune environments in validated systems.
Familiarity with JAMF Pro for cross-platform GxP compliance awareness.
Knowledge of GAMP 5 validation principles or equivalent regulated system frameworks.
Prior experience generating QA audit documentation or participating in validation testing for endpoint systems.
Understanding of Windows OS lifecycle management and modern endpoint management best practices.
Certifications such as Microsoft Endpoint Manager, ITIL, or CompTIA Security+.
A proactive, methodical approach to process improvement and compliance-driven automation.
Pay & Benefits
At Moderna, we believe that when you feel your best, you can do your best work. That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.
Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs
A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
Family planning benefits, including fertility, adoption, and surrogacy support
Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
Savings and investment opportunities to help you plan for the future
Location-specific perks and extras
The salary range for this role is $130,800.00 - $209,400.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.

The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.
About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.
By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.
We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.
If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Our Working Model
As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.
Moderna is a smoke-free, alcohol-free, and drug-free work environment.
Equal Opportunities
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!
Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.
Accommodations
We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected] .
Export Control Notice
This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.
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