Top 45 Senior principal mechanical engineer Jobs in Columbus

Sr Mechanical Engineer
Amgen —New Albany, OH
- $115,494.60 - $156,257.40 a year
- Doctoral degree
- Master's degree
- High school diploma or GED
- Disability insurance
- Health insurance
Senior Mechanical Engineer/Designer
M-Engineering —Westerville, OH
- Full-time
- 11+ years
- Senior level
- Professional Engineer
- Disability insurance
- Health insurance
Senior Mechanical Engineer
Sky Climber Access Solutions —Delaware, OH
- Full-time
- Analysis skills
- Continuous improvement
- Travel
- Health insurance
- Dental insurance
Quick Apply
14d
Senior Mechanical Engineer (Finite Element Analysis Focus)
Battelle —Columbus, OH
- $82,000 - $117,000 a year
- Full-time
- Hybrid work
- 5 years
- Office
- Analysis skills
- Wellness program
- Health insurance
Sr. / Principal Project Engineer (Mechanical - OH) Job
Armstrong —Hilliard, OH
- $105,000 - $132,000 a year
- Full-time
- Up to 50% travel
- 5 years
- Travel
- Disability insurance
- Health insurance
Senior Mechanical Engineer, Data Centers - Remote (U.S.)
AECOM —Columbus, OH
- $160,000 - $190,000 a year
- Full-time
- Remote
- Master's degree
- 8 years
- Travel
- AD&D insurance
- Employee stock purchase plan
Senior Manufacturing Engineer
Rogue Fitness —Columbus, OH
- Full-time
- Engineering
- 3 years
- US work authorization
Senior Mechanical Engineer
AECOM —Columbus, OH
- $130,000 - $150,000 a year
- Full-time
- Hybrid work
- 6 years
- Continuous improvement
- Mentoring
- AD&D insurance
- Employee stock purchase plan
Sr. Principal Mechanical Research Engineer
Vertiv —Delaware, OH
- Full-time
- 5 years
- Office
- Master's degree
Senior Mechanical Engineer
Battelle —Columbus, OH
- Full-time
- Hybrid work
- Office
- Master's degree
- Assembly
- Wellness program
- Health insurance
Principal Engineer
Southland Industries Inc. —Columbus, OH
- Microsoft Excel
- Management
- Construction site
- Paid parental leave
- AD&D insurance
9d
Sr. Principal Engineer Mechanical Engineering
Vertiv —Columbus, OH
- Bachelor of Science
- Travel
- Mentoring
1d
Senior Automation Engineer
ATS Automation Tooling Systems Inc. —Lewis Center, OH
- OSHA
- English
- Master's degree
Sr. Process Development Engineer– Combination Products & Device Engineer
Amgen —New Albany, OH
- $115,494.60 - $156,257.40 a year
- Hybrid work
- Doctoral degree
- Engineering
- High school diploma or GED
- Disability insurance
- Health insurance
Sr. Product Lifecycle Mechanical Engineer, DCE - Mechanical Products & Services (MPS)
Amazon Data Services, Inc. —Columbus, OH
- $136,600 - $184,800 a year
- Full-time
- Research
- 8 years
- Travel
- AD&D insurance
- Health insurance
Sr. Mechanical Controls Engineer, Controls Design eXecution
Amazon Web Services, Inc. —Columbus, OH
- $136,600 - $184,800 a year
- Full-time
- System design
- Mentoring
- Senior level
- AD&D insurance
- Health insurance
6d
Sr. Mechanical Engineer
PRIORITY DESIGNS INC —Columbus, OH
- Full-time
- Travel
- Mentoring
- Experience equivalent to degree accepted
Quick Apply
Senior Automation Engineer
Orise —Lewis Center, OH
- OSHA
- English
- Master's degree
Senior Plumbing Engineer - Mission Critical (Columbus)
Burns & McDonnell —Columbus, OH
- Full-time
- 6 years
- Construction site
- Master's degree
- 401(k)
- Employee stock ownership plan
Sr. Design Engineer
Southland Industries Inc. —Columbus, OH
- Microsoft Excel
- Construction site
- Engineering
- Paid parental leave
- AD&D insurance
7d

I want to receive the latest job alert for senior principal mechanical engineer in columbus

By signing in to your account, you agree to SimplyHired's Terms of Service and consent to our Cookie and Privacy Policy.

Explore jobs in more locations

senior principal mechanical engineer jobs near columbus

Principal Software Engineer jobs in Columbus, OH

Senior Mechanical Engineer jobs in Columbus, OH

Senior Design Engineer jobs in Columbus, OH

Senior Process Engineer jobs in New Albany, OH

Senior Manufacturing Engineer jobs in Columbus, OH

Senior Mechanical Engineer jobs in Delaware, OH

Principal Software Engineer jobs in New Jersey

Principal Software Engineer jobs in Morristown, NJ

Assistant Principal jobs in Pittsburgh, PA

Blue Seal Engineer jobs in New Jersey

Principal Software Engineer jobs in Frisco, TX

Principal Software Engineer jobs in Framingham, MA

Principal Software Engineer jobs in Wisconsin

School Principal jobs in Dallas, TX

Principal Software Engineer jobs in Palmdale, CA

Principal Software Engineer jobs in Hawthorne, CA

Principal Software Engineer jobs in Redmond, WA

Senior Mechanical Engineer jobs in Austin, TX

Senior Mechanical Engineer jobs in Aurora, IL

Mechanical Engineer jobs in Detroit, MI

Sr Mechanical Engineer

Amgen -
New Albany, OH

Apply Now

Job Details

$115,494.60 - $156,257.40 a year

Benefits

Disability insurance
Health insurance
Dental insurance
Flexible spending account
Vision insurance
Retirement plan

Qualifications

Quality control corrective actions
Manufacturing equipment maintenance
Bachelor's degree in mechanical engineering
Performance improvement leadership
Project engineering
Chiller
Doctoral degree
Operations management
Team leadership
Technical documentation
Pharmaceutical regulatory compliance
Preventive action implementation
Coaching
Mechanical Engineering
Technical writing experience within manufacturing
Engineering project drawing management
Engineering process optimization
Facilities maintenance regulatory compliance
Corrective and preventive actions (CAPA)
GMP
Project management experience in manufacturing
Technical support
Master's degree
High school diploma or GED
Analysis skills
Production validation processes
Task prioritization
Pharmaceutical company experience
Industry trends
Collaboration with manufacturing teams

Full Job Description

US - Ohio - New Albany

JOB ID: R-245988 LOCATION: US - Ohio - New Albany WORK LOCATION TYPE: On Site DATE POSTED: May. 29, 2026 CATEGORY: Engineering SALARY RANGE: 115,494.60USD -156,257.40 USD

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr. Mechanical Engineer

What you will do

Let’s do this. Let’s change the world. In this role the Utilities Senior Engineer is responsible for handling the maintenance and implement projects related to the utilities at the New Albany, OH Advanced Assembly and Packing Facility. The Senior Engineer is responsible to ensure a safe, effective, efficient, and cost appropriate operations & maintenance programs.

Responsibilities:

Provide leadership for 24/7 field support to identify, and resolve utilities and facilities issues.
Own the equipment’s and/or systems related to the site utilities.
Have deep technical understand of (Boilers, Chillers, Compressed Air, and HVAC).
Stay in sync with Current Good Manufacturing Practices to ensure utility systems are compliant.
Own and maintain related drawing and P&IDs.
Provide coaching and technical expertise to the technicians to support the infrastructure operations.
Identify and implement opportunities to improve equipment & process reliability and minimize impact of maintenance activities to ongoing operations.
Provide leadership to continuously improve strategies throughout the site and across all shifts.
Collaborate with key customers and support groups regarding operations & maintenance activities and strategies.
Collaborate with Facilities & Engineering peers within the Amgen manufacturing network.
Ensure activities are accomplished in a safe manner in accordance with cGMP requirements and expectations.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Engineering professional we seek will possess these qualifications.

Basic Qualifications:

Doctorate degree

Or

Master’s degree and 2 years of Maintenance or Engineering experience

Or

Bachelor’s degree and 4 years of Maintenance or Engineering experience

Or

Associate’s degree and 8 years of Maintenance or Engineering experience

Or

High school diploma / GED and 10 years of Maintenance or Engineering experience

Preferred Qualifications:

Bachelor’s Degree in Mechanical Engineering
6+ years’ experience in engineering or maintenance or related function within the biotechnology and/or pharmaceutical and/or medical device industry
5+ years’ experience and track record of ensuring compliance in a highly regulated environment
5+ years’ experience in engineering project management
5+ years’ experience in process and/or machine validation
3+ years’ experience in CAPA process management
Technical experience with critical and non-critical utilities systems (Example: HVAC, Compress Air, Boilers, etc.)
Ability to manage multiple tasks and optimally set priorities
Technical writing skills

Competencies:

Established Leadership capabilities
Passion for Operational Excellence
Financial savvy
Communications skills, both oral and written, including executive presentation skills
Interpersonal and facilitation skills to forge consensus among competing client interests while ensuring objectives are met
Ability to tactfully negotiate and positively influence peers and executive leadership
Analytical skills to identify potential improvement opportunities
Knowledge of industry trends (e.g., regulatory and compliance, technology, human performance programs, sustainability, etc.)

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Apply Now

Refine Your Search

senior principal mechanical engineer jobs in columbus