Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Senior Director, Global Safety & Risk Programs
What you will do
Let’s do this. Let’s change the world! The Senior Director, Global Safety & Risk Programs is a strategic enterprise leader responsible for defining and executing Amgen's global safety and operational risk strategy. This role leads the transformation, governance, and continuous evolution of enterprise safety programs to enable sustainable business growth, operational excellence, innovation, and organizational resilience.
Reporting to the Head of Global Environment, Health & Safety (EHS), this leader partners across Operations, Global Engineering, Research & Development, Product Stewardship, Corporate Functions, Security, and Digital Technology & Innovation to modernize safety management systems, accelerate digital transformation, and integrate risk management into business decision-making.
This role will champion innovation, leverage emerging technologies and AI-enabled insights, strengthen enterprise capabilities, and build an integrated safety culture that enables Amgen to deliver with greater speed, agility, and confidence.
Key Responsibilities
Enterprise Strategy & Transformation
Develop and execute Amgen's enterprise Safety & Risk strategy aligned with corporate priorities and long-term business objectives.
Lead the transformation and modernization of global safety programs to improve organizational effectiveness and operational performance.
Establish a multi-year roadmap to evolve enterprise safety capabilities, governance, and risk management practices.
Benchmark leading biotechnology, pharmaceutical, and high-reliability organizations to continuously improve enterprise capabilities.
Foster a culture of innovation, agility, and continuous improvement across the global EHS organization.
Innovation & Digital Enablement
Drive innovation by integrating AI, predictive analytics, automation, and digital technologies into enterprise safety programs.
Develop advanced dashboards and leading indicators that enable proactive risk management and executive decision-making.
Champion digital transformation initiatives that simplify processes, improve user experience, and increase organizational efficiency.
Evaluate emerging technologies to strengthen workforce protection and operational resilience.
Global Safety & Critical Risk Programs
Provide enterprise leadership and governance for:
Occupational Safety
Critical Risk Management
Serious Injury & Fatality (SIF) Prevention
Contractor Safety Excellence
Human & Organizational Performance (HOP)
Control of Work
Electrical Safety
Machine Safety
Confined Space
Lockout/Tagout
Working at Heights
Ergonomics
Powered Industrial Vehicles
Line-of-Fire Prevention
Learning Teams & Operational Learning
Ensure programs remain scalable, standardized, and adaptable to evolving business needs.
Enterprise Risk Management
Advance enterprise risk management capabilities through data-driven decision-making and systems thinking.
Establish governance for identifying, assessing, and mitigating operational risks across the enterprise.
Integrate risk management into capital projects, engineering design, manufacturing operations, R&D, and business planning.
Develop enterprise risk intelligence and predictive capabilities that improve organizational resilience.
Operational Excellence & Organizational Effectiveness
Lead initiatives that simplify processes, eliminate unnecessary complexity, and improve execution across the enterprise.
Drive integration between safety, engineering, quality, operations, and continuous improvement initiatives.
Ensure safety programs enable productivity, innovation, and operational performance rather than acting as standalone compliance activities.
Promote systems thinking and cross-functional collaboration to improve end-to-end business performance.
Culture, Leadership & Change Management
Lead enterprise change management efforts that strengthen safety culture and organizational performance.
Build leadership capability in Human & Organizational Performance (HOP), learning culture, and risk-based decision-making.
Partner with senior leaders to embed safety into business transformation initiatives.
Foster psychological safety, frontline engagement, accountability, and continuous learning.
Governance, Assurance & Compliance
Establish enterprise governance frameworks that ensure consistency, transparency, and accountability.
Monitor program effectiveness through KPIs, leading indicators, and executive dashboards.
Lead enterprise audits, assessments, and management reviews.
Ensure compliance while advancing innovative approaches that improve business value.
Talent & Organizational Capability
Build and develop a high-performing global organization capable of supporting future business needs.
Coach and mentor emerging leaders.
Develop critical technical capabilities and succession plans.
Foster an inclusive, collaborative, and innovation-driven culture.
The successful leader will:
Lead the transformation of Amgen's global safety and risk programs to meet future business needs.
Accelerate digital innovation and AI adoption across EHS.
Improve enterprise risk visibility, predictive capabilities, and decision-making.
Strengthen organizational resilience and critical risk management.
Enable safer, faster, and more efficient business execution.
Increase cross-functional integration and operational effectiveness.
Build a high-performing organization that continuously innovates and adapts.
Position Global EHS as a strategic business partner that enables growth, operational excellence, and long-term enterprise success.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional individual we seek is a leader with these qualifications
Basic Qualifications:
Doctorate degree and 5 years of leading transformation safety and risk experience OR
Master’s degree and 9 years of leading transformation safety and risk experience OR
Bachelor’s degree and 11 years of leading transformation safety and risk experience AND
In addition to meeting at least one of the above requirements, you must have at least 5 years’ experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation of resources. Your managerial experience may run concurrently with the required technical experience referenced above
Preferred Qualifications:
Demonstrated success leading enterprise transformation initiatives within biotechnology, pharmaceutical manufacturing, engineering, or similarly regulated industries like oil and gas.
Proven experience driving organizational transformation, innovation, and digital modernization.
Strong system-thinking mindset with the ability to simplify complex global organizations.
Experience leveraging AI, advanced analytics, and digital technologies to improve business performance.
Expertise in enterprise risk management, organizational resilience, and operational excellence.
Experience influencing executive leadership and leading change across complex matrix organizations.
Strong business acumen with the ability to balance risk, innovation, and execution.
Exceptional strategic thinking, executive communication, and stakeholder management skills.
Critical Leadership Competencies
Strategic Leadership
Enterprise Transformation
Innovation & Digital Mindset
Systems/Process Thinking
Organizational Effectiveness
Business Enablement
Operational Excellence
Executive Influence
Change Leadership
Risk Intelligence
AI & Digital Adoption
Continuous Improvement
Organizational Resilience
Cross-Functional Integration
Data-Driven Decision Making
Talent Development
Collaboration & Influence
Customer & Patient Focus
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
and make a lasting impact with the Amgen team.
careers.amgen.com
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Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
