Top 527 Clinical research scientist Jobs in Boston, Ma

Scientist, Pre-Clinical Biomarkers and Translational Research
Keros Therapeutics —Lexington, MA
- $133,000 - $157,000 a year
- Master's degree
- Analysis skills
- Doctor of Philosophy
Senior Clinical Research Scientist
Merck KGaA —Billerica, MA
- $131,300 - $216,600 a year
- 3 years
- Doctor of Philosophy
- Neurology
- Health insurance
- Paid time off
11d
Clinical Research Coordinator to Home-Based CRA (Clinical Research Associate)
Medpace, Inc. —Boston, MA
- Full-time
- Remote
- Mid-level
- Office
- Driver's License
- Health insurance
- Paid time off
3d
Oncology Research Nurse
Brigham and Women’s Hospital —Boston, MA
- $41.71 - $105.65 an hour
- Full-time
- Nursing
- RN License
- Mid-level
- Health insurance
- Dental insurance
Clinical Research Coordinator
The Vascular Care Group —Wellesley, MA
- $60,000 - $70,000 a year
- Hybrid work
- Patient monitoring
- Clinic experience
- Mid-level
Quick Apply
Clinical Research Coordinator – Ophthalmology
Andover Eye Associates Inc —Andover, MA
- From $28 an hour
- Part-time
- Patient monitoring
- HIPAA
- Mid-level
Quick Apply
Clinical Data Scientist - AI Trainer
DataAnnotation —Waltham, MA
- $50 - $100 an hour
- Part-time
- Remote
- Computer Science
- English
- Mid-level
- Flexible schedule
Quick Apply
Clinical Researcher — Night Shift
Orbit Technologies, Inc. —Charlestown, MA
- $30 - $50 an hour
- 8 hour shift
- In-person
- Entry level
- Relocation assistance
Quick Apply
Clinical Data Scientist - AI Trainer
DataAnnotation —Dedham, MA
- $50 - $100 an hour
- Part-time
- Remote
- Computer Science
- English
- Mid-level
- Flexible schedule
Quick Apply
Clinical Data Scientist - AI Trainer
DataAnnotation —Cambridge, MA
- $50 - $100 an hour
- Part-time
- Remote
- Computer Science
- English
- Mid-level
- Flexible schedule
Quick Apply
Region Manager
Care Access —Boston, MA
- $95,000 - $115,000 a year
- Up to 50% travel
- Inventory management
- Pass drug screening
- Health savings account
- Paid holidays
Postdoctoral Research Fellow - Polymer Chemistry/Biomaterials
Boston Children's Hospital —Dorchester, MA
- From $70,000 a year
- Urgently hiring
- Laboratory experience
- University
- Doctor of Philosophy
- Health savings account
- Health insurance
Quick Apply
Associate Director, Clinical Operations Program Lead
Takeda Pharmaceutical —Boston, MA
- $154,400 - $242,550 a year
- Remote
- English
- Bachelor's degree
- Conflict management
- Paid holidays
- Disability insurance
Early Development Project Leader
Sanofi EU —Cambridge, MA
- $148,500 - $214,500 a year
- Master's degree
- Bachelor's degree
- Doctor of Philosophy
- Parental leave
15h
Research Project Manager
VA Boston Healthcare System —Boston, MA
- $84,579 - $109,959 a year
- Full-time
- Background check
- Microsoft Excel
- HIPAA
- Health savings account
- Health insurance
Quick Apply
13d
Research Coordinator
VA Boston Healthcare System —Boston, MA
- Full-time
- Background check
- Mid-level
- Administrative experience
- Health savings account
- Health insurance
Quick Apply
11d
Vice President of Clinical Research Development
Mangrove Management Partners —Burlington, MA
- $140,000 - $200,000 a year
- Hospital
- Office
- Outpatient experience
Quick Apply
Ophthalmic Research Technician/Associate
New England College of Optometry —Boston, MA
- $70,000 a year
- Full-time
- Spanish
- 5 years
- English
- Paid holidays
- Disability insurance
Quick Apply
Principal Clinical Trial Manager
TransMedics, Inc. —Andover, MA
- $137,100 - $193,700 a year
- Full-time
- Bachelor of Science
- Office
- Master's degree
- Employee stock purchase plan
- Disability insurance
Quick Apply
Central Study Coordinator - Retention
Care Access —Boston, MA
- $65,000 - $75,000 a year
- Remote
- Spanish
- Computer literacy
- Writing skills
- Health savings account
- Paid holidays

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Scientist, Pre-Clinical Biomarkers and Translational Research

Keros Therapeutics -
Lexington, MA

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Job Details

$133,000 - $157,000 a year

Qualifications

Data integrity assurance
Immunological assays
Data visualization software proficiency
Molecular biomarkers
Technical documentation
Immunological laboratory techniques
Design of experiments
Flow cytometers
Assay development
Data integrity and documentation
In vivo studies
Research findings presentation
Cytometry
Data visualization projects
Cross-functional communication
Data analysis software
Molecular analysis

Full Job Description

At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients.

Job Summary

In the role of Scientist, Preclinical Biomarkers and Translational Research, you will join the Bioanalytical Sciences group to advance novel biologic programs from pre-clinical to clinical development. You will partner closely with Biology, Toxicology, and other cross-functional teams to translate biological questions into biomarker strategies; design and execute hypothesis-driven studies; develop fit-for-purpose assays; analyze preclinical samples; and interpret results in the context of TGF-beta superfamily biology, mechanism of action, PK/PD, efficacy, and safety. This is a highly hands-on research position requiring strong scientific judgement, rigorous experimental design, excellent bench and in vivo skills, and clear communication of actionable conclusions.

Primary Responsibilities

Partner with Biology, Toxicology and other cross-functional teams to identify critical biological questions and establish biomarker strategies for target engagement, pharmacodynamic activity, efficacy, disease biology, and potential safety findings.
Independently generate scientific hypotheses and design, execute, and interpret in vitro, ex vivo, and in vivo studies that clarify mechanism of action and support program decisions.
Develop, optimize, qualify, and troubleshoot fit-for-purpose biomarker assays using relevant platforms such as ELISA/MSD, qPCR, Western blotting, immunoprecipitation, multicolor flow cytometry, and cell-based assays.
Perform hands-on analysis of serum, plasma, tissue, and cellular samples from preclinical studies, including tissue processing, tissue dissociation, primary cell isolation, and ex vivo functional analyses.
Evaluate commercial kits, antibodies, reagents, and assay platforms; develop custom methods when needed; and ensure assay performance, reproducibility, data integrity, and appropriate documentation.
Present study designs, data, interpretations, limitations, and recommendations at project team meetings and contribute to study reports, technical documents, publications, and patent-related activities.
Support assay transfer and external CRO activities under the guidance of the Director of Bioanalysis, as needed.

Core Competencies (Required Skills)

Strong research ability, including hypothesis generation, experimental design, assay troubleshooting, and critical data interpretation
Good understanding of TGF-β superfamily biology, related signaling pathways, and their roles in disease mechanisms.
Hands-on experience within vivo models, tissue collection and processing, and preclinical sample analysis.
Technical expertise in relevant methods such as ELISA, MSD, qPCR, Western blotting, flow cytometry, and mammalian cell culture, and experience developing and optimizing biomarker assays.
Strong quantitative analysis and data visualization skills using GraphPad Prism, FlowJo, or comparable software, with careful attention to reproducibility and data integrity.
Strong collaboration, scientific communication, documentation, and data-presentation skills.

Preferred Skills

Experience supporting biologic drug-discovery programs.
Experience applying TGF-beta pathway biology to preclinical, target validation, mechanism-of-action, or biomarker studies.
Experience with MSD, Luminex, multiplex assays, flow cytometry.
Experience with primary cells, ex vivo assays, gene perturbation, or novel disease-model development.

Education Requirements

Ph.D. in molecular biology, cell biology, immunology, cancer biology, pharmacology, biochemistry, biotechnology, or a closely related discipline, with at least 2 years of relevant industry and/or postdoctoral research experience, or a Master's degree with at least 10 years of relevant industry experience.

Our Diversity, Equity & Inclusion Mission Statement: Keros is an inclusive company. We believe that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing all of our Keros team members.

Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.

Recruitment & Staffing Agencies:
Keros Therapeutics does not accept unsolicited resumes from any source other than the candidate directly. Any unsolicited submission by an agency to Keros is prohibited. Any resume submitted by an agency without a signed contract or expressed consent by a member of the Keros Therapeutics Human Resources Department, will be considered property of Keros Therapeutics, and no fee shall be owed with respect thereto.

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Refine Your Search

clinical research scientist jobs in boston, ma

Scientist, Pre-Clinical Biomarkers and Translational Research

Senior Clinical Research Scientist

Clinical Research Coordinator to Home-Based CRA (Clinical Research Associate)

Oncology Research Nurse

Clinical Research Coordinator

Clinical Research Coordinator – Ophthalmology

Clinical Data Scientist - AI Trainer

Clinical Researcher — Night Shift

Clinical Data Scientist - AI Trainer

Clinical Data Scientist - AI Trainer

Region Manager

Postdoctoral Research Fellow - Polymer Chemistry/Biomaterials

Associate Director, Clinical Operations Program Lead

Early Development Project Leader

Research Project Manager

Research Coordinator

Vice President of Clinical Research Development

Ophthalmic Research Technician/Associate

Principal Clinical Trial Manager

Central Study Coordinator - Retention

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