Top 1027 Optimization engineer Jobs in Boston, Ma

Senior Manager, Tech Support
Vertex Pharmaceuticals —Boston, MA
- $136,800 - $205,200 a year
- Full-time
- 6 years
- Bachelor of Science
- Bachelor's degree
- Loan repayment program
- Dental insurance
Hollowcore Engineer/Scientist
Manpower Engineering —Boston, MA
- $160,000 - $200,000 a year
- Full-time
- Mid-level
- 3 years
- Analysis skills
- Health savings account
- Disability insurance
Quick Apply
Sr Manufacturing Engineer
Honeywell Aerospace —Woburn, MA
- Full-time
- Senior level
Site Reliability Engineer, Infrastructure
TEKNICLOUD —Boston, MA
- Full-time
- Remote
- Computer science
- Computer Science
- Mid-level
Senior Systems Engineer
Humana —Boston, MA
- $97,900 - $133,500 a year
- Full-time
- Remote
- Master's degree
- Travel
- Organizational skills
- Paid parental leave
- Paid holidays
Field Service Engineer
TMC —Massachusetts
- $80,000 - $100,000 a year
- Full-time
- Up to 50% travel
- Military
- Data analysis skills
- Health insurance
- Dental insurance
Quick Apply
Sr. Facilities Engineer
Ultragenyx Pharmaceutical —Bedford, MA
- $157,800 - $194,900 a year
- Full-time
- Bachelor of Science
- System design
- Ability to climb stairs
- Gym membership
5d
Simulation Engineer - AI Trainer
DataAnnotation —Boston, MA
- $40 - $60 an hour
- Part-time
- Remote
- Computer Science
- English
- Mid-level
- Flexible schedule
Quick Apply
Data Platform Engineer, Senior Associate
The Housing Partnership Network —Boston, MA
- $111,200 - $125,100 a year
- Hybrid work
- Computer Science
- Salesforce
- Mid-level
- Health savings account
- Paid holidays
Quick Apply
Mechanical Engineer
Viridien —Acton, MA
- $110,000 - $120,000 a year
- Full-time
- 5 years
- Master's degree
- Analysis skills
- Health savings account
- Health insurance
Advanced Lead - Systems Engineering Integrator
GE Aerospace —Lynn, MA
- $128,800 - $171,350 a year
- Full-time
- Engineering
- Pass drug screening
- 3 years
- Paid parental leave
- Disability insurance
Lead Sustainability Engineer
RMF Engineering, Inc —Boston, MA
- Full-time
- 5 years
- System design
- Office
- Paid holidays
- Health insurance
Quick Apply
Autonomy Software Engineer
MORSE Corp —Cambridge, MA
- $90,000 - $210,000 a year
- Computer science
- Bachelor of Science
- Analysis skills
Quick Apply
Principal SAP PaPM Configuration Engineer
Liberty Mutual —Boston, MA
- $120,000 - $225,000 a year
- Full-time
- Hybrid work
- Master's degree
- SQL
- Analysis skills
Controls Engineer
Viridien —Acton, MA
- $130,000 - $140,000 a year
- Full-time
- 5 years
- Laboratory experience
- Analysis skills
- Health savings account
- Health insurance
SAP PaPM Configuration Engineer
Liberty Mutual —Boston, MA
- $83,000 - $154,000 a year
- Full-time
- Hybrid work
- Mid-level
- SQL
- Analysis skills
Embedded Firmware Engineering Manager
Analogic Corporation —Canton, MA
- Management
- Computer Science
- Master's degree
- Health savings account
- Health insurance
Quick Apply
Principal Quantitative Engineer, Investments Technology
Liberty Mutual —Boston, MA
- $128,000 - $225,000 a year
- Full-time
- Hybrid work
- Computer science
- Computer Science
- 5 years
AI Engineer
Suffolk Construction Company, Inc. —Boston, MA
- $170,000 - $222,600 a year
- Full-time
- Computer Science
- Office
- Master's degree
- Commuter assistance
- Fuel card
Principal Full Stack Software Engineer, Investments Technology (Public Markets)
Liberty Mutual —Boston, MA
- $128,000 - $225,000 a year
- Full-time
- Hybrid work
- Computer science
- Computer Science
- System design

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optimization engineer jobs near boston, ma

Senior Manager, Tech Support

Vertex Pharmaceuticals -
Boston, MA

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Job Details

Full-time
$136,800 - $205,200 a year

Benefits

Loan repayment program
Dental insurance
Tuition reimbursement
Paid time off
Vision insurance
401(k) matching

Qualifications

Stakeholder management

Full Job Description

Job Description

General Summary

Reporting to the Senior Director, Manufacturing Operations, this role is responsible for developing and executing the Technical Support strategy for technology transfer, product commercialization, and lifecycle management. The individual will also support key manufacturing systems and processes, including change controls, risk assessments, deviations, and GMP documentation.

This role leads and mentors the Technical Support team and provides oversight for technology transfer, process optimization, continuous improvement initiatives, and manufacturing process performance monitoring. The Senior Manager will collaborate cross-functionally with Process Development (PD), Analytical Development (AD), Quality Control (QC), Operational Quality, Materials Management, Operations, and other stakeholders to enable efficient process transfer and sustained manufacturing performance.

Key Duties and Responsibilities:

Lead Technical Support initiatives, contribute to strategy development, and manage team resources to achieve Manufacturing Operations objectives.
Oversee the sustained performance and continuous improvement of cell and gene therapy manufacturing processes.
Lead a team of manufacturing engineers and specialists supporting the technology transfer and continuous improvement of equipment, processes, and control systems.
Represent Technical Support and Operations at cross-functional daily management meetings, maintaining visibility to technical issues and action plans across the manufacturing floor.
Serve as the primary escalation point for manufacturing issues; coordinate resolution with subject matter experts and communicate status to management.
Drive structured, closed-loop problem solving to improve manufacturing performance, including uptime and yield; identify root causes and implement sustainable corrective actions.
Establish and lead process performance monitoring and improvement strategies, including optimization, lifecycle management, and operational excellence. Use aligned KPIs to identify and close performance gaps.
Partner with cross-functional stakeholders to promote phase-appropriate design for manufacturability and improve manufacturing performance.
Own the development of internal master batch records, SOPs, work instructions, and related documentation required for technology transfer, in collaboration with Development and Quality.
Support deviation management, CAPA, and change control activities, as needed. Serve as the process SME for Quality, Supply Chain, Manufacturing, and other functions. Support manufacturing investigations, including OOS, OOT, and root cause analyses.
Ensure compliance with all regulatory, corporate, and Quality System requirements.

Knowledge and Skills:

Demonstrated experience in process development, technology transfer, process optimization, technical operations, and lifecycle management.
Strong technical problem-solving, technical writing, and presentation skills. Lean Six Sigma Green Belt or Black Belt preferred.
Strong sense of urgency, with the ability to escalate issues promptly and communicate transparently with stakeholders and management.
Ability to work independently with minimal supervision, manage multiple priorities, and support several projects simultaneously.
Strong interpersonal, collaboration, and teamwork skills.

Education and Experience:

BS or MS in Chemical Engineering or a related discipline.
Minimum of 6 years of experience in cell and gene therapy manufacturing, biopharmaceutical manufacturing, or a related pharmaceutical environment.
Minimum of 3 years of people management experience preferred.

Pay Range:

$136,800 - $205,200

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

Apply Now

Refine Your Search

optimization engineer jobs in boston, ma

Senior Manager, Tech Support

Hollowcore Engineer/Scientist

Sr Manufacturing Engineer

Site Reliability Engineer, Infrastructure

Senior Systems Engineer

Field Service Engineer

Sr. Facilities Engineer

Simulation Engineer - AI Trainer

Data Platform Engineer, Senior Associate

Mechanical Engineer

Advanced Lead - Systems Engineering Integrator

Lead Sustainability Engineer

Autonomy Software Engineer

Principal SAP PaPM Configuration Engineer

Controls Engineer

SAP PaPM Configuration Engineer

Embedded Firmware Engineering Manager

Principal Quantitative Engineer, Investments Technology

AI Engineer

Principal Full Stack Software Engineer, Investments Technology (Public Markets)

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