Top 531 Senior principal scientist Jobs in Boston, Ma

Pathology Senior Principal Research Scientist
Vertex Pharmaceuticals —Boston, MA
- $180,000 - $270,000 a year
- Full-time
- Doctor of Philosophy
- Mentoring
- 1 year
- Loan repayment program
- Dental insurance
Senior Principal Scientist
Sanofi —Cambridge, MA
- $148,500 - $214,500 a year
- Hybrid work
- 7 years
- Doctor of Philosophy
- Senior level
- Parental leave
Senior/Principal Scientist, Computational Biology
Cellular Intelligence —Boston, MA
- $150,000 - $225,000 a year
- Full-time
- Computer Science
- 3 years
- Doctor of Philosophy
Senior Principal Scientist - Translational Muscle Biology
UCB —Cambridge, MA
- Presentation skills
- Doctor of Philosophy
- Neurology
Senior Scientist II/Principal Scientist, Molecular Cloning Technologies
Flagship Pioneering, Inc. —Cambridge, MA
- $143,000 - $214,500 a year
- Data analysis skills
- Doctor of Philosophy
- Mentoring
- Retirement plan
Senior Principal Scientist / Assoc Director, Oncology Translational Research
Novartis —Cambridge, MA
- $138,600 - $257,400 a year
- Full-time
- 5 years
- Analysis skills
- Doctor of Philosophy
- Health insurance
- 401(k) matching
Senior Director / Director Clinical Development, Oncology
BioNTech AG —Cambridge, MA
- $168,100 - $318,300 a year
- Full-time
- Background check
- Medicine
- Mentoring
AIRx, Sr. Director, Nonclinical Safety Lead
Takeda Pharmaceutical —Boston, MA
- $212,000 - $333,190 a year
- Call employer
- Hybrid work
- 11+ years
- Business development
- Doctor of Philosophy
- Paid holidays
- Disability insurance
Research Senior Scientific Director, Head of Hit ID and Sample Management (Automation)
Takeda Pharmaceutical —Boston, MA
- $212,000 - $333,190 a year
- Hybrid work
- Bachelor of Science
- 11+ years
- Presentation skills
- Paid holidays
- Disability insurance
Physics Expert (Professor / Principal Investigator) – AI Trainer
micro1 —Boston, MA
- $80 - $160 an hour
- Contract
- Remote
- Doctor of Philosophy
- Senior level
- Leadership
- Flexible schedule
Senior Director, Research and Development
SharkNinja —Needham, MA
- $161,500 - $299,000 a year
- Engineering
- 11+ years
- Analysis skills
- Health savings account
- AD&D insurance
Senior Director, Immunology and Translation
CSL Behring —Waltham, MA
- $302,000 - $350,000 a year
- Full-time
- Hybrid work
- Medicine
- 11+ years
- Office
Sr. Director/Director Precision Oncology
Aitia —Cambridge, MA
- $180,000 - $240,000 a year
- Full-time
- 7 years
- Doctor of Philosophy
- Computer skills
Senior Scientist, Drug Product and Formulation Development
Ultragenyx Pharmaceutical —Woburn, MA
- $160,300 - $198,000 a year
- Full-time
- Master's degree
- 8 years
- Doctor of Philosophy
- Gym membership
4d
Sr. Director/Director Precision Oncology
Aitia —Cambridge, MA
- $180,000 - $240,000 a year
- Full-time
- 7 years
- Doctor of Philosophy
- Computer skills
Senior Director, Drug Safety & Pharmacovigilance – Development
Klein Hersh International —Boston, MA
- Email
- Medicine
- 5 years
- Contracts
Senior Director, AIRx Medicinal Chemistry
Takeda Pharmaceutical —Boston, MA
- $212,000 - $333,190 a year
- Full-time
- Hybrid work
- Management
- 11+ years
- Doctor of Philosophy
- Paid holidays
- Disability insurance
Senior Research Scientist – Battery and Data Center Safety
FM —Norwood, MA
- $121,000 - $173,000 a year
- Full-time
- Math
- Doctor of Philosophy
- Senior level
- 401(k)
- Tuition reimbursement
Senior Research Scientist –Flammability and Fire Dynamics
FM —Norwood, MA
- $121,000 - $173,000 a year
- Full-time
- Math
- Doctor of Philosophy
- Senior level
- 401(k)
- Tuition reimbursement
Sr. R&D Food Scientist
Home Market Foods —Norwood, MA
- $90,000 - $110,000 a year
- Microsoft Excel
- Microsoft Outlook
- Customer service
- Relocation assistance
- Health insurance
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senior principal scientist jobs near boston, ma

Pathology Senior Principal Research Scientist

Vertex Pharmaceuticals -
Boston, MA

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Job Details

Full-time
$180,000 - $270,000 a year

Benefits

Loan repayment program
Dental insurance
Tuition reimbursement
Paid time off
Vision insurance
401(k) matching

Qualifications

Mentoring
Cross-functional communication

Full Job Description

Job Description

Pathology Senior Principal Research Scientist, Vertex Pharmaceuticals (Boston)

Preclinical Safety Assessment (PSA) is a global function responsible for the design and conduct of comprehensive nonclinical safety programs for the evaluation of Vertex therapies at all stages of discovery and development. Vertex Pharmaceuticals uses cutting edge science and technology to perform robust assessments of novel therapies for the treatment of the most serious diseases with unmet medical need. Our culture enables individual empowerment where We Wins , Fearless Pursuit of Excellence , and Innovation are more than just corporate values; they are part of our everyday lives. PSA pathologists have significant roles in the drug development process beginning in early discovery and continuing through the entire drug development value chain resulting in successful registration and marketing approval.

Key Responsibilities:

Scientific leadership in the design, conduct and interpretation of pathology endpoints for animal model development, target identification/validation, and in vivo pharmacology and nonclinical biomarker development studies including the use of cutting-edge molecular diagnostic and digital imaging technologies
Prepares photographic or video images of pathology specimens for use in group or project presentations, reports, publications and/or presentations

Anatomic pathology evaluation of investigative pathology and regulatory toxicity studies from lead identification/optimization through registration and post-marketing approval
Scientific leadership in discovery, translational research, and regulatory nonclinical safety profiling activities as a key partner on cross-functional teams within Vertex, working with a high-functioning multidisciplinary team of preclinical safety and biomarker scientists including a Board-certified veterinary clinical pathologist and an extensive network of external consultants and contract research organizations
Participation in regulatory submission document preparation, poster presentations and scientific publications, including addressing queries from global health authorities
The position includes opportunities for potential additional roles including:
Preclinical safety representative on discovery and/or development project teams

Minimal Requirements :

DVM or equivalent and ACVP/ECVP board certification in veterinary anatomic pathology
PhD in a relevant scientific discipline is strongly preferred
1-3 years of experience in discovery and/or toxicologic pathology in the pharmaceutical/biotechnology sector, or in the gross and histologic assessment of laboratory animals
Practical experience using imaging technologies and molecular diagnostic pathology techniques to understand the pathologic basis of disease and support drug discovery and development would be preferred
Demonstrated excellence in oral and written communications, strong interpersonal skills, critical thinking and issue resolution skills, and scientific collaboration, guidance, and mentoring of non-DVM scientists and laboratory associates
Ability to contribute to decision making in a manner that is timely and consensus based, and to foster productive dialogue on complex topics
Experience with new modalities (genetic and cell therapies) as well as experience in IHC/ISH, multiplex imaging, digital pathology tools, and interpretation of tissue-based biomarkers would be a plus
Drive the adoption of innovative AI-powered solutions to enhance efficiency and accuracy in histopathology processes

#LI-KM4

Pay Range:

$180,000 - $270,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

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Refine Your Search

senior principal scientist jobs in boston, ma

Pathology Senior Principal Research Scientist

Senior Principal Scientist

Senior/Principal Scientist, Computational Biology

Senior Principal Scientist - Translational Muscle Biology

Senior Scientist II/Principal Scientist, Molecular Cloning Technologies

Senior Principal Scientist / Assoc Director, Oncology Translational Research

Senior Director / Director Clinical Development, Oncology

AIRx, Sr. Director, Nonclinical Safety Lead

Research Senior Scientific Director, Head of Hit ID and Sample Management (Automation)

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Senior Director, Research and Development

Senior Director, Immunology and Translation

Sr. Director/Director Precision Oncology

Senior Scientist, Drug Product and Formulation Development

Sr. Director/Director Precision Oncology

Senior Director, Drug Safety & Pharmacovigilance – Development

Senior Director, AIRx Medicinal Chemistry

Senior Research Scientist – Battery and Data Center Safety

Senior Research Scientist –Flammability and Fire Dynamics

Sr. R&D Food Scientist

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