Top 39 Vertex patient Jobs in Boston, Ma

Research Associate II, CRISPR-X - LNP
CRISPR Therapeutics, Inc. —South Boston, MA
- $85,000 - $92,000 a year
- Full-time
- Bachelor of Science
- Mid-level
- Bachelor's degree
Quick Apply
IT Support Associate (CONTRACT)
Entrada Therapeutics —Boston, MA
- Contract
- Laboratory experience
- Microsoft Office
- Continuous improvement
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Senior Clinical Trial Manager
Entrada Therapeutics —Boston, MA
- $160,000 - $185,000 a year
- Remote
- 7 years
- Bachelor of Science
- Bachelor's degree
- Disability insurance
- Health insurance
Quick Apply
Order Manager, Patient Support (Contract)
Vertex Pharmaceuticals —Boston, MA
- $65 - $75 an hour
- Full-time
- Hybrid work
- 5 years
- Mid-level
- Office
Senior Specialist, Drug Safety
CRISPR Therapeutics, Inc. —South Boston, MA
- $105,000 - $115,000 a year
- Full-time
- Nursing
- 5 years
- Bachelor's degree
Quick Apply
Associate Manager, Human Resources
Entrada Therapeutics —Boston, MA
- $98,000 - $126,000 a year
- Office
- Analysis skills
- Bachelor's degree
- Disability insurance
- Health insurance
Quick Apply
12d
Scientist II, LNP
CRISPR Therapeutics, Inc. —South Boston, MA
- $130,000 - $140,000 a year
- Full-time
- Doctor of Philosophy
- In-person
- Senior level
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Patient Safety Systems Principal Analyst, Global Patient Safety (Contract)
Vertex Pharmaceuticals —Boston, MA
- $85 - $95 an hour
- Full-time
- Computer Science
- 5 years
- Windows
GxP Maintenance Tech II- 2nd Shift
C&W Services —Boston, MA
- $36.58 - $43.04 an hour
- Full-time
- Mid-level
- Ability to lift 50 pounds
- Analysis skills
- Health savings account
- Disability insurance
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Director, Clinical Data Management
Entrada Therapeutics —Boston, MA
- $219,000 - $244,500 a year
- Remote
- Computer Science
- Bachelor of Science
- Bachelor's degree
- Disability insurance
- Health insurance
Quick Apply
7d
Process Dev Engineering Scientific Associate (Contract)
Vertex Pharmaceuticals —Boston, MA
- $31 - $33 an hour
- Full-time
- Organizational skills
- Entry level
- Under 1 year
Supply Chain Coordinator (Contract)
Vertex Pharmaceuticals —Boston, MA
- $32 - $34 an hour
- Temporary
- Mid-level
- Organizational skills
- Experience equivalent to degree accepted
10d
Senior Scientist, Oligonucleotide
CRISPR Therapeutics, Inc. —South Boston, MA
- $145,000 - $155,000 a year
- Full-time
- Presentation skills
- Doctor of Philosophy
- Mentoring
Quick Apply
Associate Manager, CMC Operations
CRISPR Therapeutics, Inc. —South Boston, MA
- $110,000 - $120,000 a year
- Full-time
- Analysis skills
- Senior level
- Communication skills
Quick Apply
8d
Senior Manager, Alliance Management
CRISPR Therapeutics, Inc. —South Boston, MA
- $150,000 - $165,000 a year
- Full-time
- Bachelor's degree
- Doctor of Philosophy
- Organizational skills
Quick Apply
Senior Specialist, Site Supply Chain Planning
CRISPR Therapeutics, Inc. —Framingham, MA
- $110,000 - $120,000 a year
- Full-time
- Oracle
- 3 years
- Warehouse experience
Quick Apply
Biostatistician Lead Consultant
Entrada Therapeutics —Boston, MA
- Part-time
- Remote
- Doctor of Philosophy
- Senior level
- Communication skills
Quick Apply
6d
Statistical Programming Contractor (16-Month Contract)
CRISPR Therapeutics, Inc. —South Boston, MA
- $70 - $80 an hour
- Full-time
- Computer science
- Computer Science
- Mid-level
Quick Apply
1d
Senior Engineer II, mRNA Process Development
CRISPR Therapeutics, Inc. —South Boston, MA
- $140,000 - $150,000 a year
- Full-time
- Doctor of Philosophy
- Mentoring
- In-person
Quick Apply
Crystallization Scientist (Contract)
Vertex Pharmaceuticals —Boston, MA
- $60 - $63 an hour
- Temporary
- Bachelor of Science
- Mid-level
- Bachelor's degree
7d

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Research Associate II, CRISPR-X - LNP

CRISPR Therapeutics, Inc. -
South Boston, MA

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Job Details

Full-time
$85,000 - $92,000 a year

Qualifications

Academic research projects
Nanomaterials
Pharmaceutical analysis
Drug formulation

Full Job Description

Job Description:

Company Overview

Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world’s first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.

Position Summary

We are seeking a highly motivated Research Associate II to support the design, development, and optimization of novel lipid nanoparticle (LNP) formulations to advance our non-viral delivery platform for hepatic and extra-hepatic tissues, and enable next-generation genome editing therapies from discovery through clinical translation.

The ideal candidate will bring hands-on expertise in LNP formulation development, scale-up, analytical characterization, chemistry, and process development, with a strong passion for innovation in nucleic acid delivery technologies. This individual will join the dynamic, fast-growing, and highly collaborative CRISPR-X division and contribute to both platform technology innovation and preclinical therapeutic programs.

In this role, the candidate will work cross-functionally to develop and characterize advanced delivery systems for emerging editing modalities, helping drive transformative gene editing therapies toward patients with unmet medical needs.

Responsibilities

Design, optimize, characterize, and execute lipid nanoparticle (LNP) formulations across a diverse range of lipid compositions and therapeutic payloads with minimal supervision.
Apply hands-on expertise in LNP analytical characterization techniques, including RiboGreen assays, DLS, NanoFCM, NTA, TFF, endotoxin testing, and HPLC, as well as molecular biology methods such as DNA/RNA extraction, ELISA, SDS-PAGE, PCR, and Western blotting.
Generate high-quality, reproducible datasets and maintain accurate, detailed experimental documentation in electronic laboratory notebooks (ELNs).
Perform mammalian cell culture and support in vitro studies, including transient transfection and electroporation in established cell lines. Collaborate cross-functionally with process development, analytical, and in vivo teams to support reproducible manufacturing processes and advance programs toward clinical development.
Contribute to platform innovation by investigating LNP mechanisms of action to improve delivery efficiency, therapeutic potency, and formulation stability.
Present experimental results, technical findings, and project updates to cross-functional teams and broader organizational audiences.
Effectively manage multiple priorities and projects in a fast-paced, highly collaborative research environment.

Minimum Qualifications

BS or MS in Chemistry, Chemical Engineering, Biochemistry, or a related scientific discipline.
Relevant industry or academic research experience:
- Research Associate II: 2-5+ years with a bachelor’s degree or 0-2+ years of relevant experience with a master’s degree
Hands-on experience in lipid nanoparticle (LNP) formulation and analytical characterization for nucleic acid and targeted delivery applications.
Strong understanding of drug delivery systems and gene editing therapeutics.
Demonstrated ability to work independently while contributing effectively within a fast-paced, results-driven, and collaborative research environment.
Highly organized with strong scientific rigor, problem-solving skills, and attention to detail.

Preferred Qualifications

Experience with high-throughput formulation screening and knowledge of microfluidic mixing process.
Prior experience of ionizable lipid design, bioconjugation, and process development preferred.
Prior experience with scale-up and large-scale manufacturability development of LNPs.
Understanding of RNA engineering, molecular biology, and hands-on experience of maintaining cells and performing in vitro transfection.

Competencies

Collaborative – Openness, One Team
Undaunted – Fearless, Can-do attitude
Results Orientation – Delivering progress toward our mission. Sense of urgency in solving problems.
Entrepreneurial Spirit – Proactive. Ownership mindset.

Due to the nature of their work, our manufacturing and lab-based positions are located fully on-site.

Research Associate II: Base pay range of $85,000 to $92,000 + discretionary bonus, equity and benefits.

The range provided is CRISPR Therapeutics’ reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities.

CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.

To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy

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Refine Your Search

vertex patient jobs in boston, ma

Research Associate II, CRISPR-X - LNP

IT Support Associate (CONTRACT)

Senior Clinical Trial Manager

Order Manager, Patient Support (Contract)

Senior Specialist, Drug Safety

Associate Manager, Human Resources

Scientist II, LNP

Patient Safety Systems Principal Analyst, Global Patient Safety (Contract)

GxP Maintenance Tech II- 2nd Shift

Director, Clinical Data Management

Process Dev Engineering Scientific Associate (Contract)

Supply Chain Coordinator (Contract)

Senior Scientist, Oligonucleotide

Associate Manager, CMC Operations

Senior Manager, Alliance Management

Senior Specialist, Site Supply Chain Planning

Biostatistician Lead Consultant

Statistical Programming Contractor (16-Month Contract)

Senior Engineer II, mRNA Process Development

Crystallization Scientist (Contract)

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