Top 451 Senior scientist Jobs in Brookline, Ma

Analytical Development Senior Scientist
Vertex Pharmaceuticals —Boston, MA
- $122,400 - $183,600 a year
- Full-time
- 5 years
- Bachelor of Science
- Writing skills
- Loan repayment program
- Dental insurance
9d
Scientist/Senior Scientist, Immunology
Raven —Cambridge, MA
- $150,000 - $170,000 a year
- 5 years
- Doctor of Philosophy
- Organizational skills
Research Scientist/Senior Scientist
Silent Spring Institute —Newton, MA
- $105,000 - $225,700 a year
- Email
- US work authorization
- Senior level
- Health insurance
- Dental insurance
Senior Scientist, Process Development
CEDENT —Watertown, MA
- Weekends as needed
- Bachelor's degree
- Doctor of Philosophy
- Senior level
Senior Scientist, Bioanalytical Sciences
CEDENT —Cambridge, MA
- 5 years
- Doctor of Philosophy
- Quality control
Senior Scientist, I
AbbVie —Waltham, MA
- $96,500 - $183,500 a year
- Full-time
- No experience needed
- Master's degree
- 8 years
- Paid holidays
- Health insurance
Senior Scientist, NHP Study Lead / Analyst
Stylus Medicine —Cambridge, MA
- $160,000 - $175,000 a year
- Master's degree
- Doctor of Philosophy
- Travel
Senior Scientist
BPG Bio, Inc —Waltham, MA
- $120,000 - $150,000 a year
- Full-time
- Doctor of Philosophy
- Neurology
- Senior level
Quick Apply
Senior Scientist Immunology
CEDENT —Boston, MA
- Doctor of Philosophy
- Senior level
- 4 years
Senior Scientist, Automated Purifications & Separations
AstraZeneca —Cambridge, MA
- $118,870 - $178,306 a year
- Master's degree
- Bachelor's degree
- Doctor of Philosophy
- Health insurance
- Dental insurance
3d
Scientist II/Senior Scientist, Protein Sciences – Cell Binding Assays
Manifold Bio —Boston, MA
- $125,000 - $175,000 a year
- 3 years
- Doctor of Philosophy
- Senior level
- Paid holidays
- Health insurance
Senior Scientist, Upstream Process Development
Stylus Medicine —Cambridge, MA
- $155,000 - $170,000 a year
- Bachelor of Science
- Bachelor's degree
- Doctor of Philosophy
- Opportunities for advancement
Senior / Principal Scientist, Biochemistry
Treeline Biosciences —Watertown, MA
- $158,000 - $184,000 a year
- 5 years
- Doctor of Philosophy
- Mentoring
Quick Apply
3d
Senior Scientist, Analytical Development
Aurion Biotech Inc. —Cambridge, MA
- $155,000 - $170,000 a year
- Research
- 3 years
- Doctor of Philosophy
- Health insurance
- Flexible spending account
Scientist-Senior Scientist-Biology Lead-Kidney Experience
RAPTOR MEDICINES INC —Boston, MA
- $120,000 - $150,000 a year
- Full-time
- 8 years
- Doctor of Philosophy
- Senior level
- Health insurance
- Paid time off
Quick Apply
Senior Director / Director Clinical Development, Oncology
BioNTech AG —Cambridge, MA
- $168,100 - $318,300 a year
- Full-time
- Background check
- Medicine
- Mentoring
Senior Scientist, Drug Product and Formulation Development
Ultragenyx Pharmaceutical —Woburn, MA
- $160,300 - $198,000 a year
- Full-time
- Master's degree
- 8 years
- Doctor of Philosophy
- Gym membership
4d
Senior Director, Research and Development
SharkNinja —Needham, MA
- $161,500 - $299,000 a year
- Engineering
- 11+ years
- Analysis skills
- Health savings account
- AD&D insurance
Research Senior Scientific Director, Head of Hit ID and Sample Management (Automation)
Takeda Pharmaceutical —Boston, MA
- $212,000 - $333,190 a year
- Hybrid work
- Bachelor of Science
- 11+ years
- Presentation skills
- Paid holidays
- Disability insurance
Sr. Director/Director Precision Oncology
Aitia —Cambridge, MA
- $180,000 - $240,000 a year
- Full-time
- 7 years
- Doctor of Philosophy
- Computer skills

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senior scientist jobs near brookline, ma

Analytical Development Senior Scientist

Vertex Pharmaceuticals -
Boston, MA

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Job Details

Full-time
$122,400 - $183,600 a year
9 days ago

Benefits

Loan repayment program
Dental insurance
Tuition reimbursement
Paid time off
Vision insurance
401(k) matching

Qualifications

Laboratory experiment design
Experimental data reports
Chemistry research
Clinical development
5 years
Pharmaceutical regulatory compliance
Bachelor of Science
Writing skills
High-performance liquid chromatographs
Job-specific skills training (staff training program)
Continuous improvement (laboratory quality control method)
Talent development
Research project design
Master's degree
Laboratory reports
Bachelor's degree
Doctor of Philosophy
Scientific protocols
Pharmaceutical analysis
Materials analysis (analytical chemistry specialty)
Mentoring
Experimental design
Mass spectrometers (MS)
Chemistry
Research data analysis
Verification of laboratory test methods
Technical project management
Technical troubleshooting support
GMP for research safety and compliance
Senior level

Full Job Description

Job Description

General Summary

Vertex is seeking a Senior Research Scientist to join Analytical Development in Boston, MA . This role supports the advancement of transformative medicines by leading analytical chemistry activities across all stages of clinical development. The position is part of the Chromatography Subject Matter Expert (SME) team , focused on small molecules and synthetic peptides/oligonucleotides , with particular emphasis on drug substance, drug product intermediates, and drug product .

Key Duties and Responsibilities:

Lead chromatographic method development, qualification, and validation activities.
Partner with cross-functional project teams to design, oversee, and review analytical methods, validation protocols, and reports .
Serve as a technical expert in chromatographic instrumentation and method development, including specialized detectors, column screening, forced degradation, and robustness studies .
Drive continuous improvement in phase-appropriate analytical development and validation practices.
Ensure consistent, compliant method development and validation practices across the organization.
Design and execute complex, technically challenging experiments that support departmental and project goals.
Interpret data, draw evidence-based conclusions , and assess broader implications of findings.
Develop innovative solutions to technical challenges and provide scientific guidance to team members when needed.
Contribute meaningfully to project strategy and critical scientific activities within the discipline.
Help build organizational capability through staff training, mentorship, and knowledge sharing .
Apply concepts or approaches from other fields to advance scientific progress.
Perform other duties as assigned.

Knowledge and Skills:

Deep experience in analytical method development and validation .
Strong technical expertise in chromatography and related analytical techniques , including GC, LC, GC-MS, LC-MS, Karl Fischer, and spectroscopy .
Proven ability in troubleshooting, data review, and interpretation .
Strong understanding of pharmaceutical industry regulations, guidelines, and GMP practices .
Excellent organizational, project management, written, and verbal communication skills .
Ability to explain technical concepts clearly and influence diverse stakeholders.
Effective in both team-based/matrix environments and independent work .
Able to manage multiple priorities in a fast-paced environment while maintaining timelines and quality.
Strong attention to detail.
Demonstrated ability to mentor others , advance projects through scientific insight, and identify productive new experimental approaches.

Education and Experience:

Ph.D. with 2+ years or Master’s degree with 5+ years of relevant analytical development experience.
Exceptional candidates with a B.S. degree with 8+ years of advanced industry experience will also be considered.

Pay Range:

$122,400 - $183,600

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

Apply Now

Refine Your Search

senior scientist jobs in brookline, ma

Analytical Development Senior Scientist

Scientist/Senior Scientist, Immunology

Research Scientist/Senior Scientist

Senior Scientist, Process Development

Senior Scientist, Bioanalytical Sciences

Senior Scientist, I

Senior Scientist, NHP Study Lead / Analyst

Senior Scientist

Senior Scientist Immunology

Senior Scientist, Automated Purifications & Separations

Scientist II/Senior Scientist, Protein Sciences – Cell Binding Assays

Senior Scientist, Upstream Process Development

Senior / Principal Scientist, Biochemistry

Senior Scientist, Analytical Development

Scientist-Senior Scientist-Biology Lead-Kidney Experience

Senior Director / Director Clinical Development, Oncology

Senior Scientist, Drug Product and Formulation Development

Senior Director, Research and Development

Research Senior Scientific Director, Head of Hit ID and Sample Management (Automation)

Sr. Director/Director Precision Oncology

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