Top 748 Biotech scientist Jobs in California

Scientist/Senior Scientist - Biology
IASO BIOTHERAPEUTICS USA LTD —Pleasanton, CA
- From $90,000 a year
- Full-time
- 3 years
- Doctor of Philosophy
- In-person
- Health insurance
- Dental insurance
Quick Apply
2d
Research Associate, Bioscience
Biotium, Inc. Fremont, California —Fremont, CA
- $73,000 - $85,000 a year
- Full-time
- Bachelor of Science
- Laboratory experience
- Research
- Relocation assistance
- Health insurance
Quick Apply
Stem Cell Biologist
Confidential Healthcare Company —Los Angeles, CA
- $95,000 - $135,000 a year
- Full-time
- Mid-level
- Office
- Master's degree
- Health insurance
- Dental insurance
Quick Apply
1d
Scientist I - Virology
Dawar Consulting, Inc. —Foster City, CA
- $57.50 an hour
- Email
- Pass drug screening
- Mid-level
- Analysis skills
- Paid sick time
Quick Apply
1d
Scientist I - LC/MS (Bioanalytical)
BioAgilytix —San Diego, CA
- $88,000 - $99,000 a year
- Full-time
- Customer service
- Writing skills
- Mid-level
- Health savings account
- Paid holidays
Quick Apply
12d
Scientist, Biology
Medra —San Francisco, CA
- $140,000 - $175,000 a year
- Full-time
- 3 years
- Master's degree
- Machine learning
- Health insurance
- Dental insurance
Associate Scientist I
Sakura Finetek USA, Inc. —Torrance, CA
- Full-time
- Microsoft Word
- Microsoft Excel
- Software troubleshooting
Scientist II
Multiply Labs —San Francisco, CA
- $115,000 - $135,000 a year
- Choose your own hours
- Google Workspace
- Mid-level
- Master's degree
- Commuter assistance
- Paid parental leave
Scientist II - Biology
Olema Oncology —San Francisco, CA
- $150,000 - $165,000 a year
- Pass drug screening
- Mid-level
- Doctor of Philosophy
Quick Apply
Scientist – Protein Engineering – Organic Chemist: ADC Research & Development
Amgen —Thousand Oaks, CA
- $111,695.10 - $151,116.90 a year
- Doctoral degree
- Mid-level
- Master's degree
- Disability insurance
- Health insurance
Research Scientist, Life Sciences
Anthropic —San Francisco, CA
- $300,000 - $320,000 a year
- Hybrid work
- 5 years
- Office
- Bachelor's degree
- Parental leave
- Flexible schedule
Associate Scientist, Oncology Research
CytomX Therapeutics, Inc. —South San Francisco, CA
- $115,000 - $135,000 a year
- Full-time
- Maintenance
- Mid-level
- Doctor of Philosophy
Research Scientist, Life Sciences (Experimental Biology)
Anthropic —San Francisco, CA
- $300,000 - $320,000 a year
- Hybrid work
- Office
- Bachelor's degree
- Doctor of Philosophy
- Parental leave
- Flexible schedule
2h
Scientist, Membrane Protein Biochemistry
Amgen —South San Francisco, CA
- $121,792.25 - $164,777.75 a year
- Master's degree
- Bachelor's degree
- Doctor of Philosophy
- Disability insurance
- Health insurance
12d
Associate Scientist
Vivodyne —San Francisco, CA
- $95,000 - $135,000 a year
- Full-time
- Mid-level
- Master's degree
- Bachelor's degree
Biology Scientist
Apostle —Pleasanton, CA
- $75,000 - $110,000 a year
- Full-time
- No experience needed
- Doctor of Philosophy
- In-person
Associate Scientist – Protein Sciences
Kite Pharma —Foster City, CA
- $109,650 - $141,900 a year
- Full-time
- Medicine
- Mid-level
- Bachelor's degree
- Health insurance
- Dental insurance
Scientist I, Tissue Material Sciences (Device Biology Research)
AbbVie —Irvine, CA
- $75,000 - $142,500 a year
- Full-time
- 5 years
- Master's degree
- Surgery
- Paid holidays
- Health insurance
Associate Scientist, Process Development (I,II,III)
Cellares —South San Francisco, CA
- $90,000 - $210,000 a year
- Full-time
- Bachelor of Science
- Maintenance
- Mid-level
- Health insurance
- Dental insurance
Scientist, Peptide Chemistry (Night Shift)
Cambrian Ops —South San Francisco, CA
- $150,000 - $220,000 a year
- Full-time
- Adults
- No experience needed
- Quality control
- Health insurance
- Dental insurance
Quick Apply
9d

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biotech scientist jobs near california

Scientist/Senior Scientist - Biology

IASO BIOTHERAPEUTICS USA LTD
Pleasanton, CA

Quick Apply

Job Details

Full-time
From $90,000 a year
2 days ago

Benefits

Health insurance
Dental insurance
401(k)
Paid time off
Vision insurance

Qualifications

Biology
Biological safety protocols
Research design
Laboratory experiment design
Advanced cell culture techniques
Molecular Biology
Research project design
Molecular cloning
Research project technical leadership
Doctor of Philosophy
Master of Science
Engineering research
Design engineering
Data interpretation
Experimental design
Chemistry, manufacturing & controls
Technical project management
Technical troubleshooting support
Production troubleshooting

Full Job Description

Scientist / Senior Scientist – Viral Vector Engineering (Lentiviral Systems)

About the Role

We are seeking a highly motivated Scientist / Senior Scientist with deep expertise in lentiviral vector engineering, cell therapy, and gene delivery technologies. The ideal candidate will play a leading role in designing, engineering, optimizing, and evaluating next-generation lentiviral systems for cell and gene therapy applications.

This position requires an individual who can independently conceive scientific strategies, design viral vectors from first principles, execute complex experiments, troubleshoot technical challenges, and drive projects from concept to completion.

Demonstrated experience designing and engineering lentiviral packaging systems beyond routine cloning or virus production is highly preferred.

Key Responsibilities

Independently design, engineer, and optimize lentiviral vector systems for research and therapeutic applications.
Develop novel lentiviral packaging plasmids, transfer vectors, and helper constructs.
Design and generate new viral variants, envelope modifications, pseudotypes, and vector mutations to improve transduction efficiency, specificity, safety, and manufacturability.
Lead molecular cloning, plasmid engineering, sequence optimization, and vector validation.
Design and execute experiments to evaluate viral infectivity, tropism, gene expression, and functional performance.
Independently identify technical bottlenecks and develop innovative solutions through systematic troubleshooting.
Optimize lentiviral production using HEK293T and other producer cell lines.
Perform lentiviral transduction of multiple primary and immortalized cell types, including human PBMCs and immune cells.
Collaborate with multidisciplinary teams to support cell therapy and gene therapy programs.
Maintain detailed documentation and present scientific findings internally and externally.
Contribute to intellectual property generation, patent applications, and scientific publications.

Required Qualifications

Ph.D. in Molecular Biology, Virology, Cell Biology, Immunology, Biomedical Engineering, or a related discipline (Scientist level). Exceptional candidates with an M.S. and extensive industrial experience will also be considered.
3–5+ years of hands-on experience in lentiviral vector development within industry or advanced academic research.
Demonstrated ability to independently design and modify lentiviral vectors, including packaging plasmids, transfer vectors, regulatory elements, and viral components.
Strong experience in molecular cloning, plasmid construction, sequence optimization, mutagenesis, and vector engineering.
Extensive experience producing high-titer lentivirus using HEK293T or equivalent producer cell systems.
Proven experience transducing primary human cells, particularly PBMCs, T cells, stem cells, and other difficult-to-transduce cell types.
Strong understanding of viral biology, transgene expression, promoter selection, vector architecture, and biosafety considerations.
Demonstrated ability to independently design experiments, interpret data, troubleshoot complex technical issues, and drive projects with minimal supervision.
Excellent communication, documentation, and project management skills.

Preferred Qualifications

Candidates with one or more of the following experiences are strongly encouraged to apply:

Inventor or co-inventor on patents related to viral vectors, gene delivery, or cell therapy.
Experience designing novel lentiviral systems with improved specificity, tropism, targeting, or manufacturing performance.
Experience utilizing AI-assisted tools or computational methods for vector design, sequence optimization, protein engineering, or experimental planning.
Experience with CAR-T, in vivo CAR-T, CAR-NK, or other engineered immune cell platforms.
Experience culturing and differentiating induced pluripotent stem cells (iPSCs), including downstream differentiation into therapeutically relevant cell types.
Experience with antibody engineering, recombinant antibody development, or biologics.
Familiarity with CRISPR/Cas-based genome editing technologies.
Experience supporting preclinical development, technology transfer, or CMC activities.
Experience working under GLP/GMP or translational research environments.

Ideal Candidate

The successful candidate is a creative scientist who enjoys solving challenging biological problems and has demonstrated the ability to independently transform scientific concepts into robust experimental solutions. We are particularly interested in candidates who have a proven track record of engineering next-generation lentiviral systems rather than simply producing standard lentiviral vectors.

If you are passionate about advancing cell and gene therapy through innovative vector engineering, we would love to hear from you.

Pay: From $90,000.00 per year

Benefits:

401(k)
Dental insurance
Health insurance
Paid time off
Vision insurance

Work Location: In person

Quick Apply

Refine Your Search

biotech scientist jobs in california

Scientist/Senior Scientist - Biology

Research Associate, Bioscience

Stem Cell Biologist

Scientist I - Virology

Scientist I - LC/MS (Bioanalytical)

Scientist, Biology

Associate Scientist I

Scientist II

Scientist II - Biology

Scientist – Protein Engineering – Organic Chemist: ADC Research & Development

Research Scientist, Life Sciences

Associate Scientist, Oncology Research

Research Scientist, Life Sciences (Experimental Biology)

Scientist, Membrane Protein Biochemistry

Associate Scientist

Biology Scientist

Associate Scientist – Protein Sciences

Scientist I, Tissue Material Sciences (Device Biology Research)

Associate Scientist, Process Development (I,II,III)

Scientist, Peptide Chemistry (Night Shift)

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